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Preoperative Nebulized Dexmedetomidine on Hemodynamic Changes in Laparoscopic Bariatric Surgery.

Dexmedetomidine Clinical Trial

Official title:
Effect of Preoperative Nebulized Dexmedetomidine on Hemodynamic Changes in Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery.

Clinical Trial Summary

This randomized study aims to evaluate the effect of preoperative dexmedetomidine nebulization on blunting hemodynamic response for laryngoscope, intubation and pneumoperitoneum in morbidly obese patients undergoing laparoscopic bariatric surgery.

Clinical Trial Description

Dexmedetomidine is an α -2 adrenergic agonist that has been proven to attenuate the hemodynamic response to intubation and pneumoperitoneum along with dose sparing effect on opioids and propofol .It has been used in multiple routes such as intravenous, intramuscular, oral, nasal, or intrathecal routes .Inhalation of nebulized drug is noninvasive and associated with high bioavailability .Nebulized Dexmedetomidine may offer an attractive alternative to both intravenous as well as intranasal routes of administration because drug deposition following nebulization takes place over nasal, buccal, as well as respiratory mucosa. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06014359
Study type Interventional
Source Tanta University
Contact Abdelhamed I Badreldin, MBBCH
Phone 00201090690631
Email ai0751294@gmail.com
Status Recruiting
Phase N/A
Start date August 27, 2023
Completion date February 1, 2024
View Details
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