Depressive Disorder, Major Clinical Trial
Official title:
Does Concurrent Hydrocortisone With Venlafaxine XR Speed Antidepressant Response?
Verified date | October 2019 |
Source | Stanford University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The primary purpose of this study is to examine whether IV hydrocortisone can speed up the time required for Venlafaxine XR to work.
Status | Completed |
Enrollment | 18 |
Est. completion date | April 2006 |
Est. primary completion date | April 2006 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria::- outpatients at least 18 years of age - current major depressive episode - HDRS greater than or equal to 21 - good physical health Exclusion Criteria:- history of sensitivity, intolerance, or non-response to venlafaxine - history of sensitivity to hydrocortisone - history of bipolar 1 illness - meets DSM-IV criteria for a current or past psychotic disorder - meets DSM-IV criteria for substance abuse or dependence in previous 6 months - significant imminent suicide risk - medical condition that would compromise participation in the study - woman of child bearing potential not using adequate birth control in the opinion of the investigator |
Country | Name | City | State |
---|---|---|---|
United States | Stanford University School of Medicine | Stanford | California |
Lead Sponsor | Collaborator |
---|---|
Stanford University | Wyeth is now a wholly owned subsidiary of Pfizer |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | To determine if treatment of major depression with hydrocortisone concurrent with starting venlafaxine XR speeds onset of antidepressant action. | |||
Secondary | To determine if hydrocortisone pre-treatment augments venlafaxine XR response. |
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