Depression Clinical Trial
Official title:
Behavioural Profiling of Disease-related Cognitive and Motor Impairment With Focus on Dopaminergic Effects in Parkinson's Disease and Potential Correlation to Biomarkers.
NCT number | NCT06275633 |
Other study ID # | H-18055648 |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | |
Last updated | |
Start date | March 19, 2019 |
Est. completion date | July 30, 2023 |
Verified date | February 2024 |
Source | University Hospital Bispebjerg and Frederiksberg |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
In this project, patients with Parkinson's Disease (PD) will be characterized by measuring cognitive and motor function and relation to effect of Levodopa. Participants will be patients with Parkinson's Disease and healthy controls. It will be investigated if there is a difference between patients with a good measured Levodopa response and with a poor measured response.
Status | Completed |
Enrollment | 68 |
Est. completion date | July 30, 2023 |
Est. primary completion date | December 3, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 90 Years |
Eligibility | Inclusion Criteria: - Age of minimum 18 - Diagnosis of PD - Be able to cooperate, understand and participate in the project - Signed informed consent, including consent to being included in the Biobank Exclusion Criteria: - Dementia - Treatment with anti-dopaminergic medication. |
Country | Name | City | State |
---|---|---|---|
Denmark | University Hospital Bispebjerg and Frederiksberg | Copenhagen | Region Hovedstaden |
Lead Sponsor | Collaborator |
---|---|
University Hospital Bispebjerg and Frederiksberg |
Denmark,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Cognitive function | The Montreal Cognitive Assessment (MoCA) | Baseline | |
Other | Depressive symptoms | BDI, Beck Depression Inventory | Baseline | |
Other | Impulsivity | QUIP, Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease-Rating Scale | Baseline | |
Primary | Motor improvement | Unified Parkinson's disease rating scale, motor part (UPDRS-3) OFF medication compared to ON medication | Baseline to end of Levodopa challenge test, approximately 3-4 hours | |
Secondary | Cognitive function | Cognitive computer tests | Baseline to end of Levodopa challenge test, approximately 3-4 hours |
Status | Clinical Trial | Phase | |
---|---|---|---|
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