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Dose-Response Effect Exercise and Depression

Depression Clinical Trial

Official title:
Dose-Response Effect of Exercise on Depression and Brain-Derived Neurotrophic Factor (BDNF) in Sedentary Young Adults

Clinical Trial Summary

The present study aims to address gaps in the literature by evaluating the objectively measured dose-response relationship between exercise and depression symptoms; examining changes in resting (Brain-derived Neurotrophic Factor) BDNF from baseline to week 10 of an exercise intervention; and assessing varying exercise intensities on enjoyment, affect, and health-related quality of life in sedentary young adult college students.

Clinical Trial Description

This 10-week randomized single-blind controlled trial will consist of an exercise intervention and attention control condition. A two-week familiarity trial period will be followed by 8 weeks of structured exercise. Objectively measured physical activity will be remotely monitored via Fitbit to examine its effect on depressive symptoms in sedentary young adult college students. Approximately 48 enrolled college students ages 18 - 25 will be recruited for the proposed study and randomized with a 1:1:1 allocation to one of the following conditions: 1. high-dose (HD) moderate to vigorous physical activity (MVPA) (n=16) 2. moderate-dose (MD moderate to vigorous physical activity (MVPA) (n=16) 3. a walking (W) attention control (n=16) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06166095
Study type Interventional
Source University of Central Florida
Contact Amoy Fraser, PhD, CCRP, PMP
Phone 4072668742
Email amoy.fraser@ucf.edu
Status Recruiting
Phase N/A
Start date July 1, 2023
Completion date December 1, 2024
View Details
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