Adolescent Depression: Video Ads on Instagram

Depression Clinical Trial

Official title:

Reducing Depression-related Stigma and Increasing Help-seeking Intentions: a Randomized Trial of Video Ads on Instagram

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05755165
• Other study ID #: 2000028980_e
• Secondary ID: No NIH funding
• Status: Recruiting
• Phase: N/A
• Start date: September 2024
• Est. completion date: March 2025

Study information

• Verified date: April 2024
• Source: Yale University
• Contact: Andres Martin, MD, MPH
• Phone: 2034942355
• Email: andres.martin[@]yale.edu
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purposes of this study are to test among adolescent viewers the utility of different types of selfie short video-based messaging to:

1. Reduce stigma and self-stigma related to depression, and

2. Increase treatment-seeking intentions.

Description:

Intervention videos will each be self-recorded videos (of ~90-second duration) featuring the same underage professional (ages 16) acting as simulated participant. The investigators will post three brief videos ('video Ads') to achieve similar exposure among Instagram users, 14-18-year-old. The videos are: (a) depression video; (b) depression video adjusted to race experiences, and (c) control videos. All videos will feature by the same Black adolescent girl.

The investigators intend to assign ~10,000 individuals aged 14-18 in a randomized way, in equal proportions, and stratified by sex and race, to view one of the three videos.

Outcomes will include:

1. Primary outcome: engagement (a composite of likes, shares, comments, and views)

2. Secondary outcome: clicks on a designated link at the end of the video ad.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 10000
• Est. completion date: March 2025
• Est. primary completion date: March 2025
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 14 Years to 18 Years

Eligibility

Inclusion Criteria:

• English-speaking

• Living in the US

• Ages 14 - 18

Exclusion Criteria:

• None

Related Conditions & MeSH terms

• Depression
• Depressive Disorder
• Stigmatization

Intervention

Behavioral:
• Depression
~90-second selfie video of an adolescent discussing her history of depression, treatment, and recovery
• Depression, adjusted
~90-second selfie video of an adolescent discussing her history of depression, treatment, and recovery - and including explicit reference to the role of anti-Black racism as a contributing factor
• Control
~90-second selfie video of an adolescent discussing everyday activities and interests, with no reference to depression or racism.

Locations

Country	Name	City	State
United States	Yale Child Center	New Haven	Connecticut
United States	Yale Child Study Center	New Haven	Connecticut

Sponsors (1)

Lead Sponsor	Collaborator
Yale University

Country where clinical trial is conducted

United States, 

References & Publications (3)

Amsalem D, Halloran J, Penque B, Celentano J, Martin A. Effect of a Brief Social Contact Video on Transphobia and Depression-Related Stigma Among Adolescents: A Randomized Clinical Trial. JAMA Netw Open. 2022 Feb 1;5(2):e220376. doi: 10.1001/jamanetworkopen.2022.0376. — View Citation

Amsalem D, Martin A. Reducing depression-related stigma and increasing treatment seeking among adolescents: randomized controlled trial of a brief video intervention. J Child Psychol Psychiatry. 2022 Feb;63(2):210-217. doi: 10.1111/jcpp.13427. Epub 2021 Apr 6. — View Citation

Martin A, Calhoun A, Paez J, Amsalem D. Destigmatizing perceptions about Black adolescent depression: randomized controlled trial of brief social contact-based video interventions. J Child Psychol Psychiatry. 2022 Nov;63(11):1270-1278. doi: 10.1111/jcpp.13570. Epub 2022 Jan 23. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Engagement composite	A sum of views, likes, shares, and comments on Instagram.; The composite is an ordinal number ranging from 0 to n; higher values indicate greater engagement with the Instagram add.	Day 1: within 10 minutes of viewing the ad
Secondary	Clicks on designated link	The number of clicks on a designated link at the end of the video ad.; Clicks are an ordinal number ranging from 0 to n; higher values indicate greater engagement with the Instagram add.	Day 1: within 10 minutes of viewing the ad