Improving Mental Health Among the LGBTQ+ Community

Depression Clinical Trial

Official title: Improving Mental Health Among the LGBTQ+ Community Impacted by the COVID-19 Pandemic

Status Recruiting

Clinical Trial Summary

The overall aim of this program of research is to improve the mental health of people who identify as LGBTQ+ by increasing their social support through a brief intervention. The purpose of the proposed project is to establish the effectiveness of our empirically-supported, brief acceptance-based behavioral therapy (ABBT). To achieve the specific aims, the investigators will conduct a fully-powered, randomized clinical trial (n=240) with two treatment arms: treatment-as-usual (TAU) vs. ABBT.

Clinical Trial Description

During the COVID-19 pandemic, up to 81% of adults in the United States experienced worsening mental health. A major cause was the social isolation triggered by the pandemic due to quarantining, loss of family or friends, and loss of work. For individuals who lost social connections or were unable to adapt to maintain their connections, social support decreased and loneliness worsened, putting them at much higher risk for anxiety and depressive symptoms. Importantly, people who identify as LGBTQ+ have been particularly affected by the social isolation caused by the pandemic and were already at much higher risk of social isolation, loneliness, and mental illness, including suicidality, before the pandemic. The objective of this R01 fully-powered trial is to examine the effectiveness of a brief acceptance-based behavioral telehealth intervention (ABBT) to improve mental health during the COVID-19 pandemic by strengthening social support among LGBTQ+ individuals. The aims of this proposal are: (1) to examine the effectiveness of ABBT in reducing mental health morbidity by conducting a fully-powered, RCT (n=240) of ABBT vs. Treatment-as-Usual; and, (2) to examine potential mediators and moderators of ABBT treatment effects. Primary outcomes will be anxiety and depressive symptoms. ;

Related Conditions & MeSH terms

• Anxiety
• Depression

• NCT number: NCT05540067
• Study type: Interventional
• Source: Brown University
• Contact: Ethan Moitra, Ph.D.
• Phone: (401) 444-1949
• Email: ethan_moitra@brown.edu
• Status: Recruiting
• Phase: Phase 2
• Start date: January 25, 2023
• Completion date: August 31, 2025