Depression Clinical Trial
Official title:
Integration of Mental Health in HIV Clinic to Increase the Success of Antiretroviral Treatment: Screening for Depression Disorders in People With HIV in Hospitals
Integration of mental health in HIV clinics is needed in order to accelerate fast track
90-90-90 for controlling HIV. Symptoms of depression are sometimes difficult to recognize. In
people living with HIV (PLWHA), depression that fails to be recognized and uncontrolled
increases the risk of unsuccessful antiretroviral treatment and mortality.
The main purpose of this study is to estimate the proportion of depressive disorders in
people living with HIV. The study included adult HIV patients aged ≥18 years, both men and
women, who had received ARV treatment for at least six months, with no history of being
diagnosed with depression.
This study was a cross-sectional, non-intervention and multicenter in adults with HIV-AIDS
(PLWHA) who were treated at a hospital who had received ARV treatment for at least six
months, without a history of being diagnosed with depression.
Patients from HIV outpatient clinics in each research hospital were briefed on the study and
offered to participate. Furthermore, based on the assessment of inclusion and exclusion
criteria, PLWHA who meet the requirements were recruited and data were collected.
Sociodemographic data, HIV risk factors, risk behaviors, clinical characteristics such as
duration of HIV, family history of mental illness, AIDS-related illnesses, other serious
non-AIDS-related illnesses, treatment (antiretroviral (ARV) and non-ARV) and history ARV
treatment response (HIV and CD4 viral load) were collected from each participant. In
addition, a rapid screening for depressive disorders was carried out using the Patient Health
Questionnaire-9 (PHQ-9) which was translated and validated in Indonesian. The PHQ-9
questionnaire was filled in by the patient with the assistance of health personnel. The total
PHQ-9 questionnaire score were added up and the severity of depression associated with the
score was reported to the patient's physician for further management.
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