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NCT03175887 Clinical Trial

Investigational TMS Treatment for Depression

Depression Clinical Trial

Official title:
Dorsolateral Versus Medial Prefrontal TMS for Depression

Clinical Trial Details — Status: Withdrawn

Administrative data
NCT number NCT03175887
Other study ID # D17107
Secondary ID
Status Withdrawn
Phase N/A
First received
Last updated
Start date September 2021
Est. completion date September 2022

Study information
Verified date May 2021
Source White River Junction Veterans Affairs Medical Center
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study is aimed to help us learn about the effects of Transcranial Magnetic Stimulation at the forehead versus the left side of the head for treatment of Treatment Resistant Depression.

Description:

While transcranial magnetic stimulation (TMS) to the left dorsolateral prefrontal cortex (DLPFC) is an FDA approved treatment for depression, a growing and converging database suggests the medial prefrontal cortex (MPFC) may be even more critical to the neurobiology of depression and antidepressant treatment response. This study will compare the efficacy of high frequency transcranial madntic stimulation on these two sections of the brain.

Recruitment information / eligibility
Status Withdrawn
Enrollment 0
Est. completion date September 2022
Est. primary completion date August 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 21 Years to 70 Years
Eligibility Inclusion Criteria: - 21-70 years old - inadequate response to one current antidepressant medication - currently depressed Exclusion Criteria: - psychiatric comorbidities

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• TMS
Transcranial magnetic stimulation (TMS) is a noninvasive procedure that uses magnetic fields to stimulate nerve cells in the brain to improve symptoms of depression.

Locations
Country Name City State
United States White River Junction VA Medical Center White River Junction Vermont

Sponsors (1)
Lead Sponsor Collaborator
White River Junction Veterans Affairs Medical Center

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Depressive symptoms measured by the 17-item Hamilton Depression Rating Scale Depressive symptoms will be measured by the 17-item Hamilton Depression Rating Scale. Change from baseline Hamilton-17 score to follow-up visit at 1 week after final TMS intervention.
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