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The Effect of Cortisol Administration on Neural Correlates of Emotion in Depression

Depression Clinical Trial

Official title:
The Effect of Cortisol Administration on Neural Correlates of Emotion in Depression

Clinical Trial Summary

There is good evidence to suggest that the pathological version of sadness that people with Major Depression experience could be caused by the failure of the hormone cortisol to properly inhibit sadness-related brain activity in the subgenual cingulate cortex. This project investigates if the subgenual cingulate cortex has become insensitive to cortisol in patients with depression and tests for variants of the cortisol receptor genes that could predispose individuals to develop cortisol insensitivity.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02837432
Study type Interventional
Source Stanford University
Contact
Status Completed
Phase Early Phase 1
Start date July 2016
Completion date November 15, 2020
View Details
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