Use of a Novel Neuroplasticity-based Neurobehavioral Intervention for PTSD

Depression Clinical Trial

Official title:

Use of a Novel Neuroplasticity-based Neurobehavioral Intervention for PTSD - A Nationwide, Online Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01694316
• Other study ID #: IRB-24890
• Status: Completed
• Phase: N/A
• Start date: September 2012
• Est. completion date: January 2017

Study information

• Verified date: August 2018
• Source: Stanford University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The present study will explore the effectiveness of a computer based neurobehavioral intervention in alleviating symptoms and improving emotion regulation in individuals with PTSD. It will increase understanding of psychopathology at a neural-circuit level and aid development of new non-pharmacological treatment for PTSD. The study is managed by the Etkin Lab at Stanford University in California, but participants from the entire US are welcome to participate as the study is delivered online.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 54
• Est. completion date: January 2017
• Est. primary completion date: January 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• current PTSD

• internet access

Exclusion Criteria:

• lifetime psychotic disorder,

• past-year substance dependence

Related Conditions & MeSH terms

• Anxiety
• Depression

Intervention

Behavioral:
• Computerized Neurobehavioral Intervention
Targeted, computerized interventions completed from the participants' own home on a computer.

Locations

Country	Name	City	State
United States	Stanford University, Department of Psychiatry and Behavioral Sciences	Stanford	California

Sponsors (1)

Lead Sponsor	Collaborator
Stanford University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	WebNeuro Computerized Cognitive and Affective Assessment Battery	Age and gender-normed Z scores for the following measures: Sustained attention accuracy, Sustained attention lapses, Sustained attention false alarms, Working memory capacity, Visual scanning speed, Inhibition executive control, Processing speed, Maze completion executive control accuracy, Maze completion executive control speed, Immediate verbal memory, Delayed verbal memory, Inhibitory motor control accuracy, Inhibitory motor control lapses, Facial affect identification accuracy (happy, fearful, angry, sad, and disgusted), Facial affect identification speed (happy, angry, fearful, sad, or disgusted), Facial affect identity recognition accuracy (happy, angry, sad, fearful, or disgusted), Facial affect identity recognition speed (happy, sad, angry, fearful, or disgusted), Emotional conflict reaction time slowdown, Regulation of emotional conflict reaction time slowdown	Baseline and 3-month
Secondary	Clinician-assessed PTSD symptoms	Total and symptom sub scale scores from the Clinician-Administered PTSD Scale for DSM-IV (CAPS)	Baseline and 3-month

External Links

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