Depression Prevention Program for Adolescents

Depression Clinical Trial

Official title:

Depression Prevention Program for High-Risk Adolescents

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00183417
• Other study ID #: R01MH067183
• Secondary ID: R01MH067183DSIR
• Status: Completed
• Phase: N/A
• First received: September 13, 2005
• Last updated: April 23, 2012
• Start date: September 2004
• Est. completion date: May 2009

Study information

• Verified date: April 2012
• Source: University of Texas at Austin
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Interventional

Clinical Trial Summary

This study will compare the effectiveness of two programs designed to prevent depression in adolescents.

Description:

Major depression is one of the most common psychiatric disorders in adolescents. In many cases, the condition is recurrent and can result in serious psychological impairment. A high number of depressed adolescents never receive treatment; therefore, it is crucial to develop prevention programs for this disorder that are effective and can be easily disseminated. This study will evaluate and compare the effectiveness of cognitive behavior therapy (CBT) and supportive/expressive (S/E) therapy in preventing depressive symptoms in adolescents.

This study will last 2 years. Participants will be randomly assigned to receive six sessions of CBT, S/E therapy, or standard depression education over 2 years. The CBT intervention will focus on reducing negative thoughts and increasing engagement in pleasant activities. S/E therapy is designed to allow adolescents to express their negative emotions and talk about recent stressful events in a supportive environment of their peers. Surveys and psychiatric interviews will be completed by all participants and their parents at the beginning and the end of the study. The surveys and interviews will assess depressive symptoms.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 350
• Est. completion date: May 2009
• Est. primary completion date: May 2009
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 14 Years to 18 Years

Eligibility

Inclusion Criteria:

• Beck Depression Inventory score higher than 10

• Parent or guardian willing to provide informed consent

Exclusion Criteria:

• Diagnosis of depression

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Depression
• Depressive Disorder

Intervention

Behavioral:
• Cognitive behavior therapy (CBT)
Participants will complete worksheets and group discussion on how to increase positive mood and activity.
• Supportive/expressive (S/E) therapy
Participants will be encouraged to express feelings and emotions without advice giving.
• Bibliotherapy
Participants will be given a book on how to increase their mood.

Locations

Country	Name	City	State
United States	University of Texas at Austin	Austin	Texas

Sponsors (2)

Lead Sponsor	Collaborator
University of Texas at Austin	National Institute of Mental Health (NIMH)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Depressive symptoms		Measured at Year 1	No

External Links

•   Click here for information on the Austin Blues Project