Depression Clinical Trial
Official title:
Depression Prevention Program for High-Risk Adolescents
This study will compare the effectiveness of two programs designed to prevent depression in adolescents.
Major depression is one of the most common psychiatric disorders in adolescents. In many
cases, the condition is recurrent and can result in serious psychological impairment. A high
number of depressed adolescents never receive treatment; therefore, it is crucial to develop
prevention programs for this disorder that are effective and can be easily disseminated.
This study will evaluate and compare the effectiveness of cognitive behavior therapy (CBT)
and supportive/expressive (S/E) therapy in preventing depressive symptoms in adolescents.
This study will last 2 years. Participants will be randomly assigned to receive six sessions
of CBT, S/E therapy, or standard depression education over 2 years. The CBT intervention
will focus on reducing negative thoughts and increasing engagement in pleasant activities.
S/E therapy is designed to allow adolescents to express their negative emotions and talk
about recent stressful events in a supportive environment of their peers. Surveys and
psychiatric interviews will be completed by all participants and their parents at the
beginning and the end of the study. The surveys and interviews will assess depressive
symptoms.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
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