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Clinical Trial Summary

The study tries to identify whether positive expectations, induced with an active placebo nasal-spray, have effects on rumination.

Clinical Trial Description

Healthy volunteers are informed that a new application method for an antidepressant, specialised on protecting from rumination, would be tested. They will randomly be assigned to the treatment group (taking the antidepressant which is in fact an active placebo) or the no treatment control group (not taking a placebo). Then sad mood is induced by mood-suggestive music and negative autobiographic recall. Then participants in the experimental group take the "medication". Afterwards both groups are asked to focus on emotion-focused, symptom-focused and self-focused thoughts to induce rumination (e.g. "Think about what your feelings might mean."). Sadness will be assessed before and after the negative recall task and also after the rumination induction. State Rumination will be assessed before the recall task and after the rumination induction. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT03869424
Study type Interventional
Source Philipps University Marburg Medical Center
Contact Lea Rebstock, M. Sc.
Phone 064212824054
Status Not yet recruiting
Phase N/A
Start date April 20, 2019
Completion date August 31, 2019

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