Dentin Bridge Formation After Indirect Pulp Capping With Bioactive Glass Incorporated in Resin Composite and Its Adhesive in Comparison With Light Cured Calcium Hydroxide

Dental Caries Clinical Trial

Official title:

Clinical Response of Human Pulps Capped With Bioactive Glass Incorporated in Resin Composite and Adhesive

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04274920
• Other study ID #: REC16-071
• Status: Completed
• Phase: N/A
• Start date: March 1, 2017
• Est. completion date: July 1, 2018

Study information

• Verified date: February 2020
• Source: Al-Azhar University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to evaluate the effect of application of bioactive glass in different protocols on the formation of dentin bridge after indirect pulp capping using resin composite with its adhesive both are containing bioactive glass.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 36
• Est. completion date: July 1, 2018
• Est. primary completion date: May 1, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Active carious lesion in deep dentin of molars.

• Absence of cavitated lesions at the buccal or lingual surfaces as determined by clinical and radiographic examination.

• Absence of clinical diagnosis of pulp exposure, fistula, swelling of periodontal tissues, and abnormal tooth mobility;

• Absence of clinical symptoms of irreversible pulpitis, such as spontaneous pain or sensitivity to pressure;

• The extension of the carious lesion should be such that complete caries removal would risk pulp exposure, as determined by clinical and radiographic assessment;

• Absence of radiolucencies at the interradicular or periapical regions, or thickening of the periodontal spaces, that would indicate the presence of irreversible pulp pathologies or necrosis;

• Absence of internal or external root resorption.

• Co-operative patients approving the trial.

Exclusion Criteria:

• Patients with systemic medical conditions

• pregnant females

• Teeth with spontaneous pain or sensitivity to percussion.

• Teeth with periodontal lesions, internal or external root resorption, mobility of tooth, sinus opening, or abscessed tooth.

• Radiographic examination revealed, interrupted or broken lamina dura, widened periodontal ligament space, periapical radiolucency.

Related Conditions & MeSH terms

• Dental Caries
• Dental Pulp Diseases
• Pulp Disease, Dental
• Stomatognathic Diseases

Intervention

Other:
• Bioactive Glass
Bioactive glass was incorporated in resin composite and its adhesive
• Light cured calcium hydroxide
Light cured calcium hydroxide

Locations

Country	Name	City	State
Egypt	AlAzhar University, Faculty of Dentistry for Girls	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Al-Azhar University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change of dentine thickness	Thickness in millimeters using CBCT	baseline, one month, 3 months and 6 months