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Dental Caries clinical trials

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NCT ID: NCT03002792 Not yet recruiting - Anesthesia Clinical Trials

Neurodevelopment Outcomes After Pediatric Dental Caries Treatment Under General Anaesthesia

Start date: January 2017
Phase: N/A
Study type: Observational

The purpose of this study is to investigate whether early expose to general anaesthesia will influence neurodevelopment.

NCT ID: NCT02999230 Active, not recruiting - Dental Caries Clinical Trials

Probiotics That Moderate pH and Antagonize Pathogens to Promote Oral Health

Start date: February 22, 2017
Phase: N/A
Study type: Interventional

This study will examine the mechanisms of action of probiotics and synbiotics for control of oral diseases, with a particular focus on exploring new strategies for caries prevention and treatment.

NCT ID: NCT02999061 Completed - PreTerm Birth Clinical Trials

Prevalence of Dental Caries in Preterm Birth Children Aged 2-5 Years in Primary Dentition

Start date: December 2016
Phase: N/A
Study type: Observational

The purpose of the study is to determine the prevalence of dental caries in preterm birth children aged 2-5 years in primary dentition.

NCT ID: NCT02991664 Enrolling by invitation - Clinical trials for Dental Caries Class II

Clinical Performance of a Glass-ionomer Restorative System in Extended-sized Cavities

Start date: December 2015
Phase: N/A
Study type: Interventional

The aim of this clinical trial was to compare the clinical performances of a glass ionomer restorative system with a micro hybrid resin based composite in extended sized class II cavities. A total of 100 class 2 lesions were restored with a glass ionomer restorative system (Equia Forte) or a micro hybrid composite (G-aenial Posterior). Restorations were evaluated at baseline and yearly during 6 years according to the modified-USPHS criteria. Data were analyzed with Cohcran's Q and McNemar's tests (p<0.05).

NCT ID: NCT02991573 Completed - Dental Caries Clinical Trials

Clinical Study Class II on Ceram.x Universal and Prime&Bond

Start date: November 2015
Phase: N/A
Study type: Interventional

Damage to teeth from decay or previous old silver fillings can be repaired with tooth-coloured filling materials that stick to the tooth. These materials have been around for some years and have become more sophisticated; with greater ease of placement by the dentist and better durability for the patient. The fillings are designed to be used in combination with a specific glue (adhesive) that is designed to stick to the different parts of the tooth to provide a good seal, the outer enamel and the inner dentine. This study will examine the performance of a state-of-the-art modern tooth coloured filling material (Ceram X) in combination with an existing adhesive (control adhesive) and a new adhesive (Prime & Bond Universal) used in two different techniques; both of which are known to work but one is easier to apply. This results in three treatment groups. At the start of the study, the test material Prime&Bond Universal is CE-marked, as are all other medical devices used. Thus, this study is not conducted to meet any regulatory requirements. The rationale of this study is the extension of knowledge primarily concerning the clinical performance of Prime&Bond Universal in molars. Two investigators (to be confirmed) will place a minimum of 25 restorations per group (75 restorations in total) to assess the performance of the materials in a comparative design. The study restorations will be monitored for a period of 18 months (with the option to extend the evaluation period to 48 months). After placement of restorations under controlled clinical conditions, the primary objective of the study is the determination of post-operative sensitivity and pulp vitality, marginal adaptation and staining of margins of the restorations. In addition, fracture of material and retention, recurrent caries, occlusal contour and wear, approximal anatomical form will be determined as well as the failure rate as defined by the ADA.

NCT ID: NCT02988349 Completed - Dental Caries Clinical Trials

Ecological Effect of Arginine Dentifrice on Oral Microbiota

Start date: October 2013
Phase: N/A
Study type: Interventional

caries-free (CF) individuals caries-active (CA) individuals (DMFT ≥ 6) will be recruited. Subjects will be instructed to brush their teeth twice daily for 3 min using Colgate® Sensitive Pro-Relief® toothpaste (containing 8% arginine and 1450 ppm NaF) for 2 weeks. Supra- and subgingival plaque, saliva, and in situ plaque samples will be collected before and after the treatment for laboratory analyses.

NCT ID: NCT02969538 Not yet recruiting - Dental Caries Clinical Trials

Effect of Shortening the Etching Time on the Clinical Performance of Resin Composite Restorations in Primary Teeth

Start date: November 2016
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of shortening the etching time on the 18-month clinical performance of resin composite restorations in primary molars after partial carious removal. This randomized clinical trial will include subjects (5-10 year-old children) selected at Pediatric Clinic of Federal University of Santa Maria. The sample will consist of 70 primary molars presenting active cavitated carious lesions (with radiographic involvement of the outer half of the dentin), located on the occlusal surface. The sample will be randomly divided into two groups according to the etching time of the dentin prior adhesive application (Adper Single Bond 2; 3M ESPE): recommend by manufacturers (15 seconds) and half-reduced etching time (7 seconds). The restorations will be clinically followed every 6 months for up to 18-month using the FDI criteria for clinical evaluation. Survival estimates for restoration longevity will be evaluated using the Kaplan-Meier method.

NCT ID: NCT02962713 Completed - Dental Caries Clinical Trials

Giomer vs Glass Ionomer Cement for ART Occlusoproximal Restorations: a Randomized Clinical Trial

Start date: November 6, 2017
Phase: N/A
Study type: Interventional

Although the Atraumatic Restorative Treatment (ART) is well settled in the literature regarding occlusal-proximal cavities, the longevity of these restorations is still lower when compared to occlusal ones. This factor is often associated with low mechanical properties of glass ionomer cements (GIC). The objective of this randomized clinical trial is to evaluate the long-term cost-effectiveness of two different materials: an encapsulated GIC - Equia (GC Corp), compared with Giomer (Beautifill Bulk Restorative - Shofu) used as restoratives materials in occlusal-proximal ART restorations of primary molars. Children aged between 4 and 8 years, will be selected in schools in the city of Cerquilho, São Paulo. All restorations will be held following the precepts of the ART and the manufacturer's instructions. The restorations will be evaluated after 3, 6, 12, 18 and 24 months according to Roeleveld et al. (2006) criteria. To verify the survival of the restorations will be used Kaplan-Meier survival analysis and log rank test. To evaluate the association between the clinical variables, Cox regression test will be applied. For the cost analysis will be used analysis of variance. The level of significance for all tests will be considered to 5%.

NCT ID: NCT02958891 Active, not recruiting - Gingivitis Clinical Trials

Dental Health Epidemiology Among Israel Defense Forces (IDF) Recruits

Start date: March 2016
Phase: N/A
Study type: Observational

An epidemiological survey for prevalence description of dental morbidity (caries, gingivitis, dental trauma and fluorosis) among Israel Defense Forces (IDF) general recruits. Morbidity measures were collected from 700 recruits at their first day of military service in order to evaluate extent and burden of dental diseases among recruits. The data will enable the military dental services commanders to plan and implement dental services according to the dental needs.

NCT ID: NCT02953886 Completed - Caries Clinical Trials

The Effect of Silver Diamine Fluoride (SDF) on Bacteria Involved in Root or Cervical Carious Lesions

Start date: November 2016
Phase: Phase 4
Study type: Interventional

The study will compare bacteria levels in cavities before and after silver diamine fluoride (SDF) treatment.