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Dental Caries clinical trials

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NCT ID: NCT03488056 Recruiting - Dental Caries Clinical Trials

Effectiveness of ICCMS in Reducing the Incidence of Dental Caries in Children

Start date: November 16, 2017
Phase: N/A
Study type: Interventional

The aim of the present study is to evaluate the effectiveness of using the ICCMS (International Caries Classification And Management System)in reducing caries lesions incidence compared to a control group that use different criteria as a not systematic and standardized prevention strategy. The study will be performed among children attending to the social project of Social Service of Commerce (SESC), Sao Paulo. The sample will be composed of 460 children aging between 7 to 12 years old registered in CURUMIM Program from eight dental centers of SESC. A randomized controlled study with parallel group will be conducted. The centers will be randomized between the 2 strategies, defining 2 groups with 4 centers each. The experimental group that will follow the criteria defined by the ICCMS will evaluate clinical and behavioral variables, it will define: evaluation of the caries risk of the patient, evaluation of the intraoral risk, diagnosis of the caries lesion and its respective activity, plan decision individualized treatment for the patient and indication of recall interval according to the risk of caries. In the control group, children need will be solved according to rthe routinely dental practices in the center, but the determination of the child's general and intraoral risk of developing new caries lesions will not be performed nor the scheduling of specific recall intervals according to the risk.

NCT ID: NCT03480516 Completed - Quality of Life Clinical Trials

Comparison of Caries Arrested & Prevented Among SDF, NaF Varnish and Combination in Children

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

Tooth decay is one of the most common chronic infectious disease found in children worldwide and if left untreated, is rapidly progress. Severe tooth decay in children is not only affect child's health and school performance, but also has impact on the family well-being. Oral rehabilitation in children requires time, resources and effort of dental specialists, the child and parents. Caries is a destructive condition of organic and inorganic components of the tooth structures but reversible and most importantly, preventable. Topical fluoride therapy, delivered by dentists has been effectively used to speed up the repair process as well as to strengthen the surface of intact tooth structure. Topical fluoride is available in various preparations. Regular application of sodium fluoride varnish is every three months, by far, considered as effective method in preventing new caries, particularly in the high-risk children. It has the advantage of containing therapeutic concentration of fluoride and ability to flow over and stick to the tooth surface. Whereas silver ion and relatively higher fluoride concentration in Silver Diamine Fluoride (SDF) has been shown to be the most effective in harden the decay, stop the caries progress and eliminate pathogenic bacteria. It can be hypothesize that when use in combination in school children, both reagents might have synergistic effect on arresting existing caries as well as preventing new caries.

NCT ID: NCT03478748 Completed - Clinical trials for Dental Caries in Children

The Impact of Anticipatory Guidance on Early Childhood Caries: a Quasi-experimental Study

Start date: January 2, 2015
Phase: N/A
Study type: Interventional

This study aimed to compare the impact of anticipatory guidance on the caries incidence of 2-3-year-old preschool children and their 4-6-year-old siblings, as well as on their mothers' oral health literacy, as compared to the conventional Ministry of Health (MOH) programme.

NCT ID: NCT03478150 Recruiting - Dental Caries Clinical Trials

Evaluation of the Antibacterial Effect of Laser Diode and Zinc Oxide Nano Particles in Cavity Disinfection

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

this is a randomized controlled clinical trial, evaluating the antibacterial effect of laser diode and zinc oxide nano-particles when used as cavity disinfectants.Two groups, including 15 patients each, will be randomly allocated so that each group receives one of either interventions (15 patients will undergo cavity disinfection by laser diode, while the other 15 patients will undergo cavity disinfection by zinc oxide nano-particles). For each patient, a dentin sample will be taken before and after cavity disinfection. The dentin samples will be microbiologically analyzed to assess the difference in the bacterial count (out come assessment). The results will be statistically analyzed.

NCT ID: NCT03457974 Completed - Dental Caries Clinical Trials

Saliva Profiles in Children With Congenital Heart Disease

Start date: January 1, 2011
Phase: N/A
Study type: Interventional

The purpose of this study was to evaluate whether there are relationships between the salivary oxidative stress status of children with CHD directly dental caries including gender, age, salivary flow rate, salivary pH, salivary buffering capacity and drug intake such as angiotensin-converting enzyme (ACE) inhibitors. If such relationships exist, they might be employed to patient caries -prevention treatment.

NCT ID: NCT03455621 Completed - Dental Caries Clinical Trials

Effect of the Amount of Fluoride Toothpaste on Fluoride Availability in the Oral Fluids in Children

Start date: March 1, 2010
Phase: Phase 4
Study type: Interventional

The aim of the study is to determine the fluoride availability in saliva and dental biofilm after the use of increasing amounts of fluoride toothpaste. Using a crossover and blind design, 15 children (18-42 months old) had their teeth brushed with increasing amounts of fluoride toothpaste. Fluoride concentration in saliva and dental biofilm was determined up to 30 min after brushing.

NCT ID: NCT03448107 Completed - Dental Caries Clinical Trials

Comparative Effectiveness of Treatments to Prevent Dental Caries

Start date: September 20, 2017
Phase: N/A
Study type: Interventional

Dental caries (tooth decay) is the most prevalent childhood disease in the world. Multiple interventions are available to treat and prevent caries. The aim of the proposed study is to compare the benefit of silver diamine fluoride (SDF) and fluoride varnish versus fluoride varnish and glass ionomer sealants. This study is a five-year, cluster randomized, pragmatic controlled trial conducted in public elementary schools in New Hampshire.

NCT ID: NCT03442309 Completed - Quality of Life Clinical Trials

Comparative Effectiveness of School-based Caries Prevention

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Dental caries (tooth decay) is the most prevalent childhood disease in the world. Multiple interventions are available to treat and prevent caries. The aim of the proposed study is to compare the benefit of silver diamine fluoride (SDF) and fluoride varnish versus fluoride varnish and glass ionomer sealants. This study is a five-year, cluster randomized, pragmatic controlled trial conducted in public elementary schools in New York City.

NCT ID: NCT03440996 Completed - White Spot Lesion Clinical Trials

Comparison of Three Toothpastes for the Prevention and Reduction of White Spot Lesions

Start date: January 14, 2011
Phase: N/A
Study type: Interventional

The purpose of the study is to determine if Clinpro™ 5000, Clinpro™ Tooth Crème, or MI-Paste Plus has an effect on the formation and resolution of white spot lesions for patients undergoing orthodontic treatment. This study will include 90 patients in the UAB Orthodontic Clinic.

NCT ID: NCT03438045 Completed - Dental Caries Clinical Trials

Implementing a Participatory, Multi-level Intervention to Improve Asian American Health Study

Start date: May 9, 2018
Phase: N/A
Study type: Interventional

This feasibility and acceptability study will be conducted at 3 community outreach centers serving an urban, low-income Chinese population. The study will evaluate the feasibility and acceptability of implementing a partnered intervention to improve the oral and general health of low-income, urban Chinese American adults and of using remote data entry into an electronic health record (EHR). The research staff will survey a sample of Chinese American patients screened at each center about their satisfaction with the partnered intervention and about their oral health behaviors. An additional sample selected from providers [dentists and community health workers (CHW)], research staff, New York University (NYU) administrators, site directors, and community advisory board (CAB) members will participate in structured interviews about the partnered intervention. The remote EHR evaluation will include group adaptation sessions and workflow analyses via multiple recorded sessions with research staff, NYU administrators, outreach site directors, and providers (dentists and CHWs). The study will also model knowledge held by these non-patient participants (including CAB members) to evaluate and enhance the partnered intervention during and/or after the feasibility and acceptability study for use in future implementations.