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Dental Caries clinical trials

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NCT ID: NCT05946473 Not yet recruiting - Dental Caries Clinical Trials

Development of a Novel Anti-caries Chewing Gum

Start date: July 2023
Phase: N/A
Study type: Interventional

This research study is designed to evaluate the chewing gum's ability to modulate the oral microbiome in human participants, in addition to its safety.

NCT ID: NCT05943782 Not yet recruiting - Caries,Dental Clinical Trials

Evaluation of CAD/CAM Onlays Fabricated by Subtractive Versus Additive Digital Manufacturing Techniques.

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Aim of the study: The aim of this RCT is to evaluate CAD/CAM onlays fabricated by subtractive technique (brilliant crios) versus additive technique (varseosmile crown plus material), in terms of clinical functional evaluation following the FDI criteria and three-dimensional digital evaluation of the marginal and internal fit by triple scan protocol. Materials and methods: A total of 30 patients will be enrolled in the clinical trial following the eligibility criteria. Then, the patients will be randomly allocated to receive either 3D printed onlays or milled ones. A blinded operator will prepare a standardized cavity for the restoration and an impression will be performed. After designing the restoration on the Exocad software, A dentist not involved in the clinical part of the study will receive the STL file of the design and envelopes containing the information necessary only to manufacture the restorations (tooth numbers and restorative materials) to proceed with either the milling or printing procedures. Try in and cementation procedures will be similarly performed for both groups by a blinded operator. Finally, the marginal and internal fit will be evaluated by using the triple scan protocol for digital 3D assessment. Also, a baseline, six months and 12 months assessments will be performed by a blinded examiner, not involved in the clinical part for assessing the functional clinical performance of the re3stprations using the FDI criteria. Finally, the data will be statistically analyzed.

NCT ID: NCT05941429 Not yet recruiting - Clinical trials for Dental Caries in Children

Comparison of Cariostatic Effect of Nano-Silver Fluoride Versus Silver Diamine Fluoride

Start date: August 2023
Phase: Phase 1
Study type: Interventional

This study will be conducted to test the cariostatic effect of Nano Silver Fluoride in a comparison to Silver Diamine Fluoride in a group of preschool children.

NCT ID: NCT05910905 Not yet recruiting - Carious Teeth Clinical Trials

Clinical Efficacy of Preformed Pediatric Zirconia and Metal Crown

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

The study was planned to evaluate and compare the clinical success of prefabricated stainless steel crowns and zirconia crowns used in the primary molars. The study will be carried out in healthy children aged 6-9 years with caries on more than one surface of the primary molars.

NCT ID: NCT05907928 Not yet recruiting - Clinical trials for Class II Dental Caries

Radiographic Evaluation of Adaptation of Universal Adhesives

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

Class 2 restorations are analyzed to see whether or not the use of modified universal adhesive will result in similar adaptation to conventional universal adhesive.

NCT ID: NCT05875064 Not yet recruiting - Clinical trials for Dental Caries in Children

Aesthetic Restorations in Deciduous Anterior Teeth

Start date: August 1, 2023
Phase: Phase 3
Study type: Interventional

This study proposes to conduct a randomized clinical trial (RCT), composed of a sample of 194 deciduous central and lateral incisors with active cavitated lesions, simplified ICDAS C+ score, with involvement of more than two surfaces. This sample will be divided into two experimental groups, both with selective removal of carious tissue: a group in which conventional restoration will be performed using opaque resins; and another group with monochromatic resin with chameleon effect and polyvinyl crowns.

NCT ID: NCT05839548 Not yet recruiting - Clinical trials for Dental Caries in Children

Articaine Efficacy and Safety for 3 Years Old Children

Start date: June 1, 2023
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to determine the local anesthetic efficacy and safety of 4% Articaine compared 2% Mepivicaine in 3 years old children, by using infiltration technique for primary teeth that required restorative, pulp therapy, or dental extraction procedure, as assessed by measuring the pain experience during injection and treatment procedures, child's behavior during the procedure, and postoperative complications.

NCT ID: NCT05829304 Not yet recruiting - Clinical trials for Dental Caries in Children

A Comparative Clinical and Radiographic Study Of Collagen Based Pulpotomy in Cariously Exposed Vital Primary Molars

Start date: June 2023
Phase: N/A
Study type: Interventional

To assess post operative pain and survival rate after collagen based pulpotomy versus MTA pulpotomy in children with vital primary molars.

NCT ID: NCT05792800 Not yet recruiting - Caries,Dental Clinical Trials

Dental Practitioners KAP Regarding Caries Preventive Measures in Cairo and Riyadah

Start date: September 2023
Phase:
Study type: Observational

The study aims to evaluate the knowledge, attitude, and practice of dental practitioners from Cairo and Riyadh regarding caries preventive measures.

NCT ID: NCT05792215 Not yet recruiting - Caries,Dental Clinical Trials

KAP of Dental Practitioners Regarding CRA

Start date: September 2023
Phase:
Study type: Observational

The aim of the study is to evaluate the knowledge, attitude, and practice of a group of dental practitioners from Cairo and Riyadh regarding caries risk assessment and management.