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Dental Caries clinical trials

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NCT ID: NCT06003452 Not yet recruiting - Dental Caries Clinical Trials

Retention Rate And Caries Prevention Of Giomer Based Sealant With And Without Pre-Treatment With Bioactive Glass Air Abrasion In Young Adults

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Prevention of oral diseases is preferable to treatment and is the key method of achieving cost effectiveness for oral health improvement programs. Various preventive strategies for dental caries have been tried and are still being developed. The occlusal pits and fissures of posterior teeth are highly susceptible to caries because of the anatomy of pit and fissure surfaces, which favours stagnation of bacteria and substrates. Fissure sealing has been shown to be an evidence-based caries preventive method for protecting the occlusal surfaces against caries. Non- sealed teeth need to be restored approximately 50% more frequently compared to their sealed counterpart. Sealants are effective caries preventive agents as long as they remain bonded to teeth. It has been proposed that sealants should be placed on both sound teeth and incipient non-cavitated carious lesions on permanent teeth of high caries risk patients in order to prevent the onset of caries and its progression. According to the American Dental Association Guidelines for the use of pit and fissure sealants, ICDAS II codes 0, 1 and 2 are recommended for sealant application.A variety of dental materials have been used as sealants using different application techniques. Their effectiveness depends on the formation of a complete seal and is increased by correct technique and moisture control, appropriate follow-up and resealing as necessary. Resin-based conventional sealants are preferred choice, however use of phosphoric acid demineralizes the enamel layer and have elongated treatment time and is more technique sensitive.

NCT ID: NCT05980273 Not yet recruiting - Dental Caries Clinical Trials

Effectiveness of Oral Health Education Programs Among School Children, Their Mothers and Teachers in Fayyum: Cohort Study

Start date: October 9, 2023
Phase:
Study type: Observational

Cohort study to evaluate the effect of oral health educational program effect on oral health of school children, their mothers and teachers

NCT ID: NCT05979805 Not yet recruiting - Dental Caries Clinical Trials

Effectiveness of Educational Interventions in the Prevention of Caries in Patients With Orthodontics

Start date: March 15, 2024
Phase: N/A
Study type: Interventional

Dental caries is classified by the World Health Organization (WHO) as an important public health problem due to its high prevalence and incidence worldwide despite the development of public policies to combat it. It is a chronic disease that has a severe impact in terms of pain and suffering, impairment of function and effect on quality of life. During orthodontic treatments, the most common adverse event is the appearance of dental caries lesions due to increased retention, change of dental biofilm composition or difficulty of removal with conventional oral hygiene techniques. Efforts to implement various conventional preventive interventions of self-care and education have not decreased its incidence, so it is necessary to implement motivational interventions to help adolescents and young adults to make positive changes in their oral health habits, which are constant and lasting and prevent and control caries.

NCT ID: NCT05965297 Not yet recruiting - Dental Caries Clinical Trials

Comparison of Two GIC's in the Restoration of Posterior Class II Lesions in the Primary Dentition

Start date: August 2023
Phase: N/A
Study type: Interventional

This study will investigate the clinical performance of a novel restorative glass ionomer (DeltaFil, DMG) in comparison to an established restorative glass ionomer (Riva Self Cure HV, SDI) in the restoration of Class II cavities in primary molars.

NCT ID: NCT05946473 Not yet recruiting - Dental Caries Clinical Trials

Development of a Novel Anti-caries Chewing Gum

Start date: July 2023
Phase: N/A
Study type: Interventional

This research study is designed to evaluate the chewing gum's ability to modulate the oral microbiome in human participants, in addition to its safety.

NCT ID: NCT05943782 Not yet recruiting - Caries,Dental Clinical Trials

Evaluation of CAD/CAM Onlays Fabricated by Subtractive Versus Additive Digital Manufacturing Techniques.

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Aim of the study: The aim of this RCT is to evaluate CAD/CAM onlays fabricated by subtractive technique (brilliant crios) versus additive technique (varseosmile crown plus material), in terms of clinical functional evaluation following the FDI criteria and three-dimensional digital evaluation of the marginal and internal fit by triple scan protocol. Materials and methods: A total of 30 patients will be enrolled in the clinical trial following the eligibility criteria. Then, the patients will be randomly allocated to receive either 3D printed onlays or milled ones. A blinded operator will prepare a standardized cavity for the restoration and an impression will be performed. After designing the restoration on the Exocad software, A dentist not involved in the clinical part of the study will receive the STL file of the design and envelopes containing the information necessary only to manufacture the restorations (tooth numbers and restorative materials) to proceed with either the milling or printing procedures. Try in and cementation procedures will be similarly performed for both groups by a blinded operator. Finally, the marginal and internal fit will be evaluated by using the triple scan protocol for digital 3D assessment. Also, a baseline, six months and 12 months assessments will be performed by a blinded examiner, not involved in the clinical part for assessing the functional clinical performance of the re3stprations using the FDI criteria. Finally, the data will be statistically analyzed.

NCT ID: NCT05941429 Not yet recruiting - Clinical trials for Dental Caries in Children

Comparison of Cariostatic Effect of Nano-Silver Fluoride Versus Silver Diamine Fluoride

Start date: August 2023
Phase: Phase 1
Study type: Interventional

This study will be conducted to test the cariostatic effect of Nano Silver Fluoride in a comparison to Silver Diamine Fluoride in a group of preschool children.

NCT ID: NCT05910905 Not yet recruiting - Carious Teeth Clinical Trials

Clinical Efficacy of Preformed Pediatric Zirconia and Metal Crown

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

The study was planned to evaluate and compare the clinical success of prefabricated stainless steel crowns and zirconia crowns used in the primary molars. The study will be carried out in healthy children aged 6-9 years with caries on more than one surface of the primary molars.

NCT ID: NCT05907928 Not yet recruiting - Clinical trials for Class II Dental Caries

Radiographic Evaluation of Adaptation of Universal Adhesives

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

Class 2 restorations are analyzed to see whether or not the use of modified universal adhesive will result in similar adaptation to conventional universal adhesive.

NCT ID: NCT05875064 Not yet recruiting - Clinical trials for Dental Caries in Children

Aesthetic Restorations in Deciduous Anterior Teeth

Start date: August 1, 2023
Phase: Phase 3
Study type: Interventional

This study proposes to conduct a randomized clinical trial (RCT), composed of a sample of 194 deciduous central and lateral incisors with active cavitated lesions, simplified ICDAS C+ score, with involvement of more than two surfaces. This sample will be divided into two experimental groups, both with selective removal of carious tissue: a group in which conventional restoration will be performed using opaque resins; and another group with monochromatic resin with chameleon effect and polyvinyl crowns.