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NCT05277129 Clinical Trial

The Immune Response to Stroke

Dementia Clinical Trial

Official title:
The Immune Response to Stroke

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05277129
Other study ID # 2019/1252
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date June 24, 2021
Est. completion date June 6, 2029

Study information
Verified date March 2022
Source University of Oslo
Contact Andreas Lossius, MD, PhD
Phone +47 930 68 515
Email postmottak@medisin.uio.no
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Some patients develop cognitive decline after a stroke, but we don't always understand the mechanisms. It has been proposed that a proportion of the patients develop an autoimmune immune response, and that this could potentially explain the cognitive decline in some of the patients. The current study aims to investigate this hypothesis in a subgroup of patients with stroke.

Recruitment information / eligibility
Status Recruiting
Enrollment 40
Est. completion date June 6, 2029
Est. primary completion date December 31, 2025
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Stroke < 72 h - Age > 18 years Exclusion Criteria: - Brain hemorrhage verified by CT or MRI scan - Previous or present immunological disease or other serious comorbidity - Ongoing immune respons after infection or vaccination < 1 month - Cognitive without ability to understand and/or give an informed consent to participate in the study

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Analysis of post-stroke immune responses
Analysis of immune responses in peripheral blood

Locations
Country Name City State
Norway Akershus University Hospital Lørenskog

Sponsors (1)
Lead Sponsor Collaborator
University of Oslo

Country where clinical trial is conducted

Norway, 

Outcome
Type Measure Description Time frame Safety issue
Primary The B cell and T cell response in peripheral blood 1 day (subject inclusion)
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