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Dehydration clinical trials

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NCT ID: NCT02989337 Recruiting - Clinical trials for Hyperemesis; Gravidarum, With Dehydration

Endothelial Dysfunction in Hyperemesis Gravidarum

Start date: December 2016
Phase: N/A
Study type: Observational

The purpose of the study is to determine serum inflammatory adhesion molecules levels in hyperemesis gravidarum

NCT ID: NCT02668848 Recruiting - Stroke Clinical Trials

The Fluid Therapy Strategy of the Non-dehydrated Patients With Acute Ischemic Stroke.

Start date: January 2016
Phase: Phase 2/Phase 3
Study type: Interventional

The investigators previously found that a blood urea nitrogen/creatinine (BUN/Cr) ratio >15 is an independent predictor of early deterioration after acute ischemic stroke. Another study was conducted to determine whether urine specific gravity, another indicator of hydration status and one more easily obtained, is also an independent predictor of early deterioration or stroke-in-evolution (SIE) in such patients. The investigators also conducted a preliminary study, enrolling ischemic stroke patients with a BUN/Cr ratio >15 and find daily Bun/Cr based hydration help to decrease post stroke infection rate and improve 3 months functional outcome. In this study, daily urine specific gravity will be used to adjust hydration therapy in ischemic stroke patients with initial Bun/Cr ratio <15. The primary outcome is the post stroke infection rate in the first 7 days after admission, and secondary outcome is 3 months functional outcome using mRS.

NCT ID: NCT02655341 Recruiting - Clinical trials for Acute Myocardial Infarction

Hydration Status Assessment Through Body Composition Monitoring in Patients With Acute Myocardial Infarction

HYD-AMI
Start date: January 2016
Phase: N/A
Study type: Observational

Aims: - evaluate the hydric status through bioimpedance spectroscopy in consecutive acute myocardial infarction patients referred for primary PCI; - assessment of renal artery stenosis incidence through renal angiography in consecutive STEMI patients; - fully characterize the complex hydration, metabolic and endothelial profile of these patients in the attempt to define the role played by dehydration in the complex dynamics of acute myocardial infarction.

NCT ID: NCT02249845 Recruiting - Dehydration Clinical Trials

Comparing the Diagnostic Accuracy of Clinical Dehydration Scales Among Small Children

Start date: September 2014
Phase: N/A
Study type: Observational

The assessment of clinical dehydration scales diagnostic accuracy (CDS scale, WHO scale, Gorelick scale) among small children.

NCT ID: NCT02203123 Recruiting - Dehydration Clinical Trials

Ratio of Inferior Vena Cava and Aorta Diameter in Dehydrated Children

Start date: March 2014
Phase: N/A
Study type: Interventional

- There is no definite tool for measurement of dehydration in children - Subjective clinical dehydration scale is considered as valuable scoring system, but it cannot be reliable among clinicians sometimes. - Some authors found Inferior vena cava/Aorta ratio can be a objective marker for dehydration - However, there is no evidence of correlation between clinical dehydration scale and inferior vena cava/aorta ratio - We will observe correlation between clinical dehydration scale and inferior vena cava/aorta ratio and change of the ratio according to hydration with intravenous normal saline infusion.

NCT ID: NCT02054585 Recruiting - Dehydration Clinical Trials

IV NaCl (Sodium Chloride) 0.9% Vs (Versus) IV NaCl 0.9% + 5% Dextrose in Pediatric ER for Dehydration

Start date: July 15, 2014
Phase: N/A
Study type: Interventional

Dehydration and refusal to eat and drink are common complaints in the Pediatric ED (Emergency Department). Most of these children have had an unsuccessful trial of oral rehydration in their community service, therefore are treated with IV rehydration. There is no consensus as to which IV solution is the best one for rehydration. Children who are unwilling or unable to eat and drink produce Keto bodies. Theoretically, addition of glucose to the IV solution would prevent catabolic metabolism and reduce the keto bodies blood concentration which should lead to a faster objective and subjective improvement of the child's condition. The proposed study is a double blind randomized clinical trial. Children will receive either NaCl 0.9% or NaCl 0.9% + 5% glucose randomly in numbered bags. The type of solution will be known to the pharmacy only. Study aims: - Primary aim: to compare the number of hospitalizations among dehydrated pediatric patients treated with either one of the IV fluids mentioned above. - Secondary aim: To evaluate for the possibility of hypoglycemia secondary to hyperinsulinism as a response to a rapid administration of glucose. Study population: The study will include 700 children 6 month to 18 years of age. It will be conducted over 18 months in the Pediatric ED of Carmel Medical Center. Currently, data regarding the use of dextrose containing solutions is lacking. As dehydration is one of the most common medical problems encountered by the physician in the pediatric ED, it is of outmost importance to evaluate the optimal IV solution used in this setting.

NCT ID: NCT01987869 Recruiting - Nausea Clinical Trials

Hiperemezis and Serotonin Elevated Serum Serotonin Levels in Hyperemesis

Start date: October 2013
Phase: N/A
Study type: Observational

Serotonin excretion was investigated in the nausea and vomiting associated with hiperemezis gravid arum.

NCT ID: NCT01939119 Recruiting - Dehydration Clinical Trials

Body-fluid Balance and Drinking Habits in Patients With Retinal Vascular Occlusion

Start date: January 2013
Phase: N/A
Study type: Observational

The purpose of this study is to examine the body-fluid balance in patients with retinal vascular occlusion and the influence of drinking habits and hemodilution on the degree of body hydration.

NCT ID: NCT01011140 Recruiting - Dehydration Clinical Trials

Physician Perceptions About Parenteral Hydration in Latin America and Spain

Start date: January 2010
Phase:
Study type: Observational

The purpose of this study is to assess palliative care physicians' attitudes, beliefs and practice patterns related to parenteral hydration at the end of life in Latin America and Spain. Objectives: 1. To assess palliative care physicians' attitudes, beliefs and practice patterns related to parenteral hydration at the end of life in Latin America and Spain. 2. To assess cross-national differences in practice patterns related to parenteral hydration at the end of life. (Latin America vs. Spain). 3. To determine the percentage of physicians who practice parenteral hydration at the end-of-life in the hospital setting and the home setting. 4. To examine the association between providers' parenteral hydration practice patterns and: - 1. provider demographic characteristics; - 2. specific characteristics of their practice settings; and - 3. training and experience in end of life care; 5. To determine which factors most predict the practice of parenteral hydration at the end of life among palliative care physicians.