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A Pilot Study of Emapalumab for the Treatment of CAR T-Cell Therapy-Associated Prolonged Cytopenia

Cytopenia Clinical Trial

Official title:
A Pilot Study of Emapalumab for the Treatment of CAR T-Cell Therapy-Associated Prolonged Cytopenia

Clinical Trial Summary

To look at the safety and effectiveness of emapalumab for the treatment of prolonged severe cytopenia in participants with LBCL who receive CART.

Clinical Trial Description

Primary Objectives: - To evaluate the efficacy of emapalumab for the treatment of prolonged severe cytopenia in participants with LBCL who receive CART. Secondary Objectives: - To evaluate safety and tolerability of emapalumab for the treatment of prolonged severe cytopenia in participants with LBCL who receive CART. Exploratory Objective: - To investigate biomarkers of response and resistance to emapalumab for the treatment of prolonged severe cytopenia in participants with LBCL who receive CART. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06285825
Study type Interventional
Source M.D. Anderson Cancer Center
Contact Paolo Strati, MD
Phone (713) 745-1776
Email pstrati@mdanderson.org
Status Not yet recruiting
Phase Early Phase 1
Start date July 31, 2024
Completion date August 22, 2028
View Details
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