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NCT04613063 Clinical Trial

Proximal Intestinal Obstruction Syndrome (PIOS) in a Patient With Cystic Fibrosis: A New Syndrome

Cystic Fibrosis Clinical Trial

Official title:
Proximal Intestinal Obstruction Syndrome (PIOS) in a Patient With Cystic Fibrosis: A New Syndrome

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04613063
Other study ID # I1568Z
Secondary ID
Status Completed
Phase
First received
Last updated
Start date October 19, 2020
Est. completion date October 21, 2020

Study information
Verified date October 2020
Source Tecnologico de Monterrey
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

A case of a patient with cystic fibrosis with bowel obstruction due to a proximal intestinal obstruction syndrome (PIOS) is presented.This syndrome can be diagnosed with the DIOS definition, with the only distinction of a more proximal location in the gastrointestinal tract, such as the stomach, the duodenum, or the jejunum.

Description:

Distal Intestinal Obstruction Syndrome is a rare complication in cystic fibrosis patients characterized by the accumulation of viscid fecal material, combined with sticky mucous secretions located in the distal ileum, adhered to the intestinal wall. Only few cases have been reported in the literature.

Recruitment information / eligibility
Status Completed
Enrollment 1
Est. completion date October 21, 2020
Est. primary completion date October 20, 2020
Accepts healthy volunteers No
Gender Male
Age group N/A and older
Eligibility Inclusion Criteria: - Adult >18 years - Cystic fibrosis - Bowel obstruction Exclusion Criteria: - Pediatric patient <18 years - Unknown cause of bowel obstruction

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Diagnostic laparoscopy
A diagnostic laparoscopy was performed where a dilated jejunum was encountered with impaction of fecal content. Surgery was converted to open surgery, where a longitudinal enterotomy of 5 cm after the transition zone was created, evacuating manually the fecal material with mucous secretion.

Locations
Country Name City State
Mexico Escuela Nacional de Medicina, Tecnologico de Monterrey Monterrey Nuevo Leon

Sponsors (1)
Lead Sponsor Collaborator
Tecnologico de Monterrey

Country where clinical trial is conducted

Mexico, 

Outcome
Type Measure Description Time frame Safety issue
Primary Bowel obstruction in a patient with cystic fibrosis A 45 year old patient with cystic fibrosis presented with bowel obstruction. Image studies were performed, without identifying a specific cause of the bowel obstruction. The patient was transferred to surgery. 3-6 days
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