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Crohn's Disease clinical trials

View clinical trials related to Crohn's Disease.

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NCT ID: NCT00844285 Completed - Crohn's Disease Clinical Trials

SECURE, the Cimzia ® Crohn's Disease Post-Marketing Registry

SECURE
Start date: January 30, 2009
Phase:
Study type: Observational

The purpose of this study is to monitor safety outcomes of patients who have taken Cimzia® as compared to a non- Cimzia® control population. The SECURE Registry's target enrollment is 3045 patients and it's objective is to monitor patients for approximately 8 years.

NCT ID: NCT00838149 Completed - Crohn's Disease Clinical Trials

Effect of Glutamine on Intestinal Permeability in Crohn's Disease

Start date: November 2005
Phase: Phase 1
Study type: Interventional

The purpose of this study is to see whether enteral glutamine supplementation improves intestinal permeability and small intestinal morphology in patients with Crohn's disease.

NCT ID: NCT00819663 Completed - Crohn's Disease Clinical Trials

Intestinal Wall Remodeling (Infliximab Therapy) in Crohn's Disease Patients Undergoing Serial Computed Tomography (CT) Enterography

Start date: February 2009
Phase: N/A
Study type: Observational

Anti-TNF therapy induces intestinal wall remodeling that correlates with clinical response and can be detected in patients undergoing serial computed tomography enterography (CTE).

NCT ID: NCT00818272 Completed - Crohn's Disease Clinical Trials

Remicade Safety Line (Crohn's Disease)(Study P03288)(COMPLETED)

Start date: December 2002
Phase: N/A
Study type: Observational

This observational study is in line with the German educational plan with the aim to implement a tool to increase and monitor the awareness for tuberculosis screening and to reinforce the patient eligibility for a treatment with Remicade according to the Summary of Product Characteristics (SmPc).

NCT ID: NCT00815061 Withdrawn - Ulcerative Colitis Clinical Trials

Epidemiology of Ulcerative Colitis and Crohn's Disease in Non Jewish Israel Population

Start date: July 2008
Phase: N/A
Study type: Observational

The aim of the present study was to describe the incidence and prevalence of IBD in non Jewish Israel population

NCT ID: NCT00810030 Completed - Ulcerative Colitis Clinical Trials

FERINJECT for Correction of Anaemia in IBD Patients, FER-IBD-COR

FER-IBD-COR
Start date: October 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine how safe, tolerable and effective the new standardised dosage regimen of FERINJECT® infusions is, compared with a well established intravenous iron treatment.

NCT ID: NCT00808262 Completed - Crohn's Disease Clinical Trials

Safety and Immunogenicity of a TNFa Kinoid in Patients With Crohn's Disease

Start date: October 2008
Phase: Phase 1/Phase 2
Study type: Interventional

Evaluation of the safety and the immune response induced by active immunization through a TNFa kinoid in patients with Crohn's disease.

NCT ID: NCT00805766 Completed - Crohn's Disease Clinical Trials

Efficacy and Safety of Increased Dose of TA-650 (Infliximab) in Patients With Crohn's Disease (CD)

Start date: December 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy, safety and pharmacokinetics after administration of 10mg/kg TA-650 every 8 weeks to patients with Crohn's disease showing an insufficient response to previous treatment with 5 mg/kg of REMICADE every 8 weeks.

NCT ID: NCT00801125 Withdrawn - Crohn's Disease Clinical Trials

Study of Tysabri (Natalizumab) in Patients Who Failed Anti-TNF-α Therapy

Start date: December 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to demonstrate the safety, tolerability and clinical benefit of TYSABRI® (natalizumab) in patients with moderately to severely active Crohn's disease.

NCT ID: NCT00798473 Completed - Osteoporosis Clinical Trials

Zoledronate for Osteopenia in Pediatric Crohn's

Start date: September 2004
Phase: Phase 3
Study type: Interventional

Background: - Up to 30% of children and adolescents with Crohn's disease have decreased bone strength, or decrease bone density, called osteopenia. - Bisphosphonates are a group of drugs that have been well studied and found to be effective in the treatment of osteopenia in menopausal women. - Zoledronate is a very potent third generation bisphosphonate, that is safe and easy to administer, and has been found effective in the treatment of menopausal women with osteopenia. Hypothesis: The investigators hypothesize that zoledronate can improve bone density in children and adolescents with Crohn's disease with osteopenia.