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NCT ID: NCT06334237 Not yet recruiting - Migraine Clinical Trials

Psychosomatic Factors Influencing the Efficacy of Holistic Care for Migraine

Start date: April 15, 2024
Phase:
Study type: Observational

This research project aims at exploring the psychosomatic factors that influence and moderate the efficacy of holistic care and personalized treatment for migraine patients. It is a prospective longitudinal observational study. The project's goal is to understand how physical, psychological, spiritual, and social factors affect the care and treatment outcomes for migraineurs. The study will include participants aged 18 to 65, who meet the International Headache Society's criteria for migraines. It will utilize a range of methodologies including questionnaires, interviews, and medical records to collect data on various factors like lifestyle, psychological state, and social support. The project will assess the effectiveness of treatments, compliance, and other outcomes such as emotional and sleep conditions.

NCT ID: NCT06331663 Not yet recruiting - Pain, Procedural Clinical Trials

SPI and Remifentanil in Skull Pin Fixation

Start date: April 1, 2024
Phase: Phase 4
Study type: Interventional

Forty patients were enrolled, and all patients used total intravenous anesthesia (remifentanil-propofol based total intravenous analgesia) as anesthesia induction and maintenance. According to the preliminary data of this department, patients who underwent intracranial surgery for skull pin fixation used remifentanil 5.0-6.0 ng/ml, while the hemodynamics is relatively stable. Therefore, when this plan is implemented, the patient needs to be under the same depth of anesthesia (monitored by electroencephalography, maintaining a value of 40-60), first start with remifentanil 5.0 ng/ml, and use the up and down method as adjust 0.5 ng/ml of concentration of remifentanil each time. Inadequate antinociception (Surgical Pleth Index(SPI) > 80 and hyperdynamics (the increased heart rate (HR) and mean blood pressure (MBP) above 20% of baseline or HR>100bpm and arterial blood pressure(ABP)>180/100mmHg)) is defined as failure, therefore we increase remifentanil by 0.5 ng/ml; otherwise, the setting is considered successful without abovementioned situations. Data collection: heart rate, mean blood pressure, Surgical Pleth Index, bispectral Index, pulse pressure variance, systolic pressure variance, concentrations of propofol and remifentanil before 2 mins, during, 5, and 15 mins of skull pin fixation were recorded and analyzed.

NCT ID: NCT06322810 Not yet recruiting - Analgesia Clinical Trials

ESP Versus PIFB for Analgesia in Open Cardiac Surgery: a Randomized Control Trial

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

This clinical trial compares analgesia efficiency and recovery outcomes between two different fascial plane block techniques (ESPB vs.PIFB) in cardiac surgery patients participant population/health conditions]. The main questions it aims to answer are: - Does ESPB provide superior analgesia than PIFB - Do patients who receive ESPB have better recovery outcomes

NCT ID: NCT06318468 Not yet recruiting - Competence Clinical Trials

The Effectiveness of Various Teaching Methods to Enhance the Comprehensive Nursing Assessment Skills of New Nurses

Start date: April 2024
Phase: N/A
Study type: Interventional

This study is going to compare different teaching strategies for improving newly recruited nurses' comprehensive nursing assessment skills.

NCT ID: NCT06317792 Not yet recruiting - Clinical trials for Parkinsonism in Diseases Classified Elsewhere

The Efficacy of Online Exergaming-Integrated Physiotherapy for Parkinson's Disease

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

To validate the efficiency of online exergaming-based physiotherapy. We will enroll patients with Parkinson's disease in postural instability and gait disturbance motor phenotype in the study and divide them into two groups in a randomized controlled study.

NCT ID: NCT06317584 Not yet recruiting - Diabetes Clinical Trials

Empowerment-based Complementary and Alternative Medicine (ECAM)

CAM
Start date: April 1, 2024
Phase: N/A
Study type: Interventional

This phase study will use a randomized trial method to evaluate the performance of the ECAM educational app in the promotion of CAM health literacy and communication among patients with diabetes.

NCT ID: NCT06315374 Not yet recruiting - Clinical trials for Chronic Pulmonary Disease

3D-Printed Aerosolized Medication Delivery Assist Device in Patients With Chronic Respiratory Diseases

Start date: March 30, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the auxiliary benefits of three-dimensional printed activating assistive devices for soft-mist inhaler on patients' utilization habit.

NCT ID: NCT06297720 Not yet recruiting - Anesthesia Clinical Trials

Early Oral Hydration After Thoracoscopic Surgery

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about the safety and feasibility of early oral hydration in patients receiving video-assisted thoracoscopic surgery after general anesthesia. The main questions aims to answer: - the safety and feasibility of oral hydration supplementation in the recovery room following general anesthesia. - the degree of improvement in sore throat and dry mouth after oral hydration. - the side effects and risks of oral hydration supplementation, such as the incidence of postoperative nausea and vomiting. - the impact of oral hydration supplementation in the recovery room following general anesthesia on hemodynamics. - patient satisfaction with oral hydration supplementation in the recovery room following general anesthesia. Participants will receive a series of oral hydration from swab moistening, and ice cube hydration to water hydration in the recovery room. Researchers will compare with the standard, no-hydration group to see if it is safe and feasible to hydrate patients in the recovery room.

NCT ID: NCT06290258 Not yet recruiting - Healthy Clinical Trials

Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder.

Start date: March 1, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

This study aims to evaluate the efficacy of fecal microbiota transplantation on the gastrointestinal symptoms, autistic symptoms and emotional behavior symptoms of patients with autism spectrum disorder, and investigate the relations between the brain-gut axis, cytokines and autism spectrum disorder. Fecal microbiota transplantation have the potentials to improve intestinal microbiota composition, regulate immunity, and then improve gastrointestinal symptoms, autistic symptoms, emotional behavior symptoms and sleep of children with autism spectrum disorder. Early intervention at school-age may even benefit development, improve cognition and prognosis.

NCT ID: NCT06290219 Not yet recruiting - Effect of Drug Clinical Trials

The Effect of Platelet-rich Plasma Nasal Injection in the Treatment of Traumatic Olfactory Dysfunction

PRP
Start date: March 20, 2024
Phase: Phase 3
Study type: Interventional

The purpose of this study is to explore the efficacy of injecting high-concentration platelet plasma combined with hyaluronic acid into the nasal olfactory mucosa in the treatment of traumatic anosmia.