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NCT ID: NCT04819815 Completed - Clinical trials for Type 1 Diabetes Mellitus

Investigation of Chronotropic Index, Exercise Capacity in Type 1 Diabetes Mellitus

Start date: January 20, 2020
Phase:
Study type: Observational

To investigate whether diabetes affects lung function and exercise capacity and impairs autonomic nervous system.

NCT ID: NCT04819711 Completed - Clinical trials for Perinatal Depression

Addressing Perinatal Depression in Deprived Areas of Istanbul, Turkey

Start date: April 5, 2021
Phase: N/A
Study type: Interventional

In Turkey, the prevalence rate of perinatal depression has been estimated between 20%-40%, reflecting the global average of 25%. Untreated perinatal depression is of concern not only because of its effect on maternal health but also from the effect that impaired maternal role fulfilment has on the mother-infant bonding and child care and the long-term impact on the infant's physical and cognitive development. Thinking Healthy Programme (THP) is an evidence-based intervention incorporated into the World Health Organization's flagship Mental Health Gap Action Programme, tailored to the perinatal period that has been shown to be effective for depressed or stressed mothers. Turkey prioritize antenatal care, and this provides an opportunity to integrate mental health care into an existing antenatal care programme. Public hospitals operate 'antenatal pregnancy schools' where women are invited to attend 5 weekly group sessions that incorporate education about pregnancy and newborn care. We have developed an on-line group version of the Thinking Healthy Programme which has been designed to be integrated into the routine on-line antenatal pregnancy classes. The intervention has been designed so it is suitable for all women (universal) rather than depressed mothers only (targeted). The aim of this study is to pilot this adapted on-line group intervention in selected hospitals' pregnancy schools. The study will be a two-arm pilot individual randomised controlled trial comparing the Thinking Healthy group intervention integrated into antenatal pregnancy school classes with antenatal pregnancy school classes alone. Our sample size of 60 pregnant women (that is 30 participants in each arm of the pilot trial), who are over 18 years old, between 12-30 weeks' gestation, and intend to attend all 5 sessions of the online antenatal classes. Participants in both arms will be assessed for depression and anxiety symptoms, levels of disability, quality of sleep, perceived social support, coping skills, and relationship with partner. All one hundred and twenty women will get a detailed assessment initially and 4-6 weeks after the intervention. Some of the study participants and antenatal nurses delivering these sessions will be approached for in-depth qualitative interviews to explore the acceptability, feasibility and perceptions of the study participants' receiving the intervention sessions.

NCT ID: NCT04819659 Completed - Anesthesia Clinical Trials

The Effect of Pharyngeal Packing on Postoperative Gastric Volume in Patients Undergoing Nasal Surgery

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Pharyngeal packing is a frequently used application to reduce the incidence and severity of postoperative nausea and vomiting (PONV) in patients who undergo nasal surgery. This study aims to research the effects of PP on gastric antral cross-sectional area (ACSA) and hence gastric volume as assessed by ultrasound, therewithal PONV and sore throat were evaluated as secondary outcomes in rhino logic surgeries (Septorhinoplasty, Septoplasty, Functional endoscopic sinus surgery).

NCT ID: NCT04819633 Completed - Uterine Leiomyoma Clinical Trials

Evaluating Serum Sestrin in Leiomyoma Patients

Start date: January 1, 2021
Phase:
Study type: Observational

Leiomyomas are the most common benign neoplasms of women's reproductive system affecting 20-30% of women within the reproductive ages. Sestrins are serum proteins which are highly expressed under circumstances of DNA damage, hypoxia and oxditive stress and play an important role in autophagia. The aim of this study is to evaluate the relationship of serum sestrin proteins with development of leiomyomas.

NCT ID: NCT04819282 Completed - Exercise Capacity Clinical Trials

Mask Usage and Physical Performance During COVID-19 Pandemic in Geriatrics

Start date: September 10, 2020
Phase:
Study type: Observational [Patient Registry]

In the COVID-19 pandemic, the use of masks in daily life has become an important issue. The most important measure taken to prevent contagion is the use of masks. The aim of the study is to determine the effects of surgical masks used in every moment of life on physical performance in elderly individuals.

NCT ID: NCT04819126 Completed - Clinical trials for Age-Related Memory Disorders

Nintendo Wii Virtual Reality Application In Dementia

Start date: January 15, 2018
Phase: N/A
Study type: Interventional

•This study was planned to investigate the effects of the Nintendo Wii virtual reality application on muscle strength and fall risk in individuals with AD. The aim of the present study is to investigate the effect of the virtual reality application on muscle strength and fall in individuals with Alzheimer' Dementia (AD).

NCT ID: NCT04819100 Recruiting - Clinical trials for Carcinoma, Non-Small-Cell Lung

A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC)

LIBRETTO-432
Start date: December 20, 2021
Phase: Phase 3
Study type: Interventional

The reason for this study is to see if the study drug, selpercatinib, compared to placebo is effective and safe in delaying cancer return in participants with early-stage non-small cell lung cancer (NSCLC), who have already had surgery or radiation. Participants who are assigned to placebo and stop the study drug because their disease comes back or gets worse have the option to potentially crossover to selpercatinib. Participation could last up to three years.

NCT ID: NCT04818996 Completed - Breast Cancer Clinical Trials

Evaluation of the Effect of Mediterranean Diet on Breast Cancer Patients

Start date: October 22, 2019
Phase: N/A
Study type: Interventional

In this study, it was aimed to evaluate the effect of the Mediterranean diet on body composition, oxidant stress and proinflammatory markers in overweight and obese breast cancer women.

NCT ID: NCT04818697 Completed - Covid19 Clinical Trials

Effect of Social Isolation on Physical Activity Level, and Kinesophobia in Heart Rhythm Disorders During Pandemic

Start date: June 24, 2020
Phase:
Study type: Observational

The aim of our study is to examine the effect of social isolation on physical activity level, health literacy and kinesophobia in heart rhythm disorders.

NCT ID: NCT04818658 Completed - Dental Caries Clinical Trials

The Preformed Metal Crowns Placed Using the Hall Technique Versus the Conventional Restoration

Start date: March 8, 2021
Phase:
Study type: Observational

The aim of this study is to compare the survival rate of the conventional restorations with the Hall Technique in carious primary molars.