There are about 15072 clinical studies being (or have been) conducted in Turkey. The country of the clinical trial is determined by the location of where the clinical research is being studied. Most studies are often held in multiple locations & countries.
Parkinson's patients suffer from respiratory distress for different reasons. It is thought that physiotherapy methods that have an indirect effect on the diaphragm can improve respiratory functions. The aim of this study is to investigate the effects of spinal mobilization and diaphragmatic breathing techniques on respiratory function.
Myofascial pain syndrome is characterized by the presence of hypersensitive points called trigger points that cause pain, tenderness, spasm, stiffness, limitation of movement, weakness, taut band within the muscle, and pain reflected by pressing in a muscle group or a single muscle. Prolotherapy is a regenerative treatment method in the treatment of chronic musculoskeletal pain, in which an irritating solution is injected, often hypertonic dextrose, into painful ligament and tendon attachments and adjacent joint spaces. In this study, it was aimed to examine the effect of prolotherapy application on pain, neck range of motion and neck disability in women with myofascial pain syndrome.
The aim of this study is to determine the level of burnout in Turkish dentists. The Copenhagen Burnout Inventory of 19 questions will be used to assess burnout; and 4 more about; gender, occupational age, institution and title. All surveys will be conducted online and we plan to reach approximately 400 participants. After the burnout levels are determined, it will be statistically investigated whether there is a difference between the groups according to gender, occupational age, institution and title.
Creative thinking is a very important factor, especially due to recent developments in technology and health. In order to adapt and contribute to these developments, creativity is also very important for the nursing profession, which is a health discipline consisting of science and art. Creative thinking skills need to be developed so that nurses can develop healthy interpersonal relationships, find solutions to the problems they encounter in their working and social life, approach the patient with a holistic perspective, use the knowledge they have acquired in education life at an optimal level in the delivery of health services, produce new information and gain a critical perspective. In today's information age, it is very important for professional development to develop the teaching models used in nursing education based on the philosophy of lifelong learning, to be revised frequently, to control the curriculum and to evaluate the effectiveness of the teaching techniques used at frequent intervals. The above-mentioned literature suggests that nurses should use creativity in their problem-solving and communication skills. In this context, it creates the need to use alternative creative thinking teaching techniques to develop nursing students' problem solving and communication skills. For this reason, the research was conducted to develop an intervention program based on creative thinking techniques in nursing education and to evaluate the effect of this program based on creative thinking techniques on problem solving and communication skills in nursing students. If a meaningful relationship is found between these variables and creative thinking education as a result of the research, the education program prepared on the subject will constitute a guide for the nursing curriculum in gaining creative thinking, problem solving and communication skills in nursing students.
Anterior cruciate ligament reconstruction (ACLR) is one of the most common procedure all around the world, however optimal graft source for ACLR still remains controversial. Although Quadriceps tendon (QT) is the least used and least studied autograft, it could be an appropriate and good alternative for ACLR. If investigaters use the same surgical technique, and exert the same rehabilitation methods they may have better results than hamstring tendon (HT) autografts.
In this study, the investigators aimed to investigate the effects of botulinum neurotoxin type A (BoNT-A) injection applied to the ankle plantar flexor muscles on lower extremity sensation and quantitative balance parameters in children with spastic hemiplegic cerebral palsy who are ambulatory without an assistive device in daily life.
150 adults patients with locally advanced or metastatic BRAFV600E mutation-positive, differentiated thyroid carcinoma who are refractory to radioactive iodine and have progressed following prior VEGFR targeted therapy will enter in the trial. Patients will be randomized in a 2:1 ratio to either dabrafenib plus trametinib or placebo. Patients will be stratified by number of prior VEGFR targeted therapy (1versus2) and prior lenvatinib treatment (yes versus no)
The EU-ROP registry is a European wide multicenter non-interventional observational registry study intended to run open-ended in as many countries as possible including infants treated for retinopathy of prematurity irrespective of the used treatment modality. The registry is strictly observational; only clinical routine data is collected, no study-specific examinations or interventions are to be performed. The aim of the EU-ROP registry is to collect information on as many patients as possible treated for ROP in Europe. Both the number of study centers as well as the number of patients to be included into the registry are not limited. The primary objective is to describe the typical clinical features of infants with severe ROP, variations in phenotype, and the clinical progression of the disease over time (natural history) in different European countries as well as to study treatment patterns, follow-up patterns, as well as long-term outcomes.
The purpose of the study is to assess if the study medication (molnupiravir, MK-4482) will prevent symptomatic coronavirus disease 2019 (COVID-19) in adults who live with someone with confirmed COVID-19 infection. This is a phase 3, multicenter, randomized, double-blind, placebo-controlled study; half of the study participants will receive molnupiravir twice daily by mouth and the other half will receive a placebo. The primary objectives of the study are to determine if molnupiravir prevents symptomatic COVID-19 disease and to evaluate its safety and tolerability. All participants who develop COVID-19 during the study are still eligible for any COVID-19 treatment recommended by their doctor.
Evaluation of Fluid Responsiveness With Pulse Variation Index and Systolic Blood Pressure Changes After Lung Recruitment Maneuver