There are about 15072 clinical studies being (or have been) conducted in Turkey. The country of the clinical trial is determined by the location of where the clinical research is being studied. Most studies are often held in multiple locations & countries.
Materials to be used as permanent filling materials in Class II restorations are still an essential field of study. This study aims to evaluate the 5-year clinical performance of Class II restorations performed with different bulk-fill restorative materials. The study was planned as an observational clinical trial. In the study, Class II restorations performed with Tetric Bulk Fill (TBF) and Filtek Bulk Fill (FBF) composites and Equia Forte Fil (EF) will be evaluated. Fifty-one patients and 119 restorations will be included in the study. Restorations will be assessed in terms of modified United States Public Health Service (USPHS) criteria during the 5th year. Cochran Q, Pearson chi-square, and Fisher-Freeman-Halton tests will be used for statistical analysis.
In this study, investigators compared the systemic inflammatory responses after percutaneous nephrolithotomy (PCNL) patients who were given an expanded empirical antibiotic regimen based on the prediction of the possibility of bacteria identified by Gram staining the first urine after renal puncture and patients whose antibiotic regimen was not performed and whose antibiotic regimen was adjusted according to patient symptoms and culture results. Investigators aimed to test its diagnostic value in predicting and preventing complications.
Musculoskeletal problems are a common health issue among individuals working in textile workshops, attributed to factors such as ergonomic risks in working conditions, personal characteristics of employees, and other workplace factors. Neck pain, back pain, shoulder pain, wrist pain, hand and finger pain, knee pain, and foot pain are frequently observed issues among those working in textile workshops, negatively impacting their functionality and quality of life. The research aims to investigate the effects of online rehabilitation education on pain and quality of life among textile workers. Participants aged between 21 and 52 working in textile workshops will be included in the study. All participants will be evaluated twice, before and after treatment, with all assessments conducted face-to-face. Demographic information such as age, gender, marital status, etc., will be assessed using a structured socio-demographic form. Pain levels will be assessed using the 100 mm VAS, quality of life will be assessed using the SF-36 questionnaire, and posture evaluation will be conducted using anterior and lateral posture analysis. The rehabilitation program administered to participants will take place over a period of 3 months, with sessions conducted three times a week on an online platform. The rehabilitation program will include posture exercises, stretching exercises, exercises for normal joint range of motion, strengthening exercises, regional pain education (shoulder, elbow, hip, wrist), and discussions on good and poor posture, lasting approximately 40-45 minutes.
Pectus deformities are among the most common anterior chest wall pathologies. Pectus excavatum is the most common chest deformity with an incidence of 0.1-0.3%. In severe deformities, a decrease in lung volume is observed. This can cause decreased pulmonary function and affect the function of the right ventricle. The diaphragm is the main respiratory muscle, and diaphragm contraction is associated with respiratory functions. So, investigators aimed to measure diaphragmatic thickness in adolescents with pectus deformity and to show whether diaphragmatic thickness is an early predictor of respiratory disorder in participants who do not show any clinical symptoms or whose respiratory functions are normal.
This study will investigate the effects of Floss band application and Mulligan mobilization on ankle range of motion, vertical jump, gait and balance in active healthy young adults.
Pulmonary embolism (PE) presents notable risks of morbidity and mortality, underscoring the need for customized anticoagulant treatment. There is a scarcity of research examining drug-related issues (DRPs) in PE. This research endeavor seeks to assess how addressing DRPs affects the clinical outcomes of PE patients receiving outpatient care, offering valuable insights to bolster patient safety measures. This study will conduct a randomized controlled trial on PE patients in Istanbul, Turkey, from January 15, 2022, to January 15, 2023. The intervention group (IG) will receive clinical pharmacist (CP) recommendations for DRPs, while the control group (CG) will undergo observation only. Evaluations will occur at 90- and 180-days post-discharge, focusing on DRPs, CP interventions, and patient outcomes. Data will be systematically recorded and analyzed, adhering to ethical standards and employing the PCNE v9.1 classification system.
Ankylosing Spondylitis (AS) is an inflammatory rheumatic disease primarily affecting the spine and sacroiliac joint. xercise is one of the most important nonpharmacologic treatment modalities in AS. Stretching, strengthening, aerobic, posture, balance and moltimodal exercise methods are the most commonly used treatment methods. The study will include 44 patients diagnosed with AS aged 18-65 years. Patients will be divided into two randomized controlled groups with 22 patients in each group. Group 1 will receive a personalized exercise program including stretching, strengthening, respiratory, aerobic and posture exercises via video conferencing. Group 2 will be recommended a video on the YouTube platform and will be asked to perform the exercises by following the content of these videos. Spinal mobility will be assessed with Bath Ankylosing Spondylitis Metrology Index, disease activity with Bath Ankylosing Spondylitis Disease Activity Index, function with Bath Ankylosing Spondylitis Function Index, quality of life with Ankylosing Spondylitis Quality of Life Scale and posture with PostureScreeen mobile application.
The research was planned in a randomized controlled trial to evaluate the effect of technology-based education provided by peers and adults to children diagnosed with asthma in the 12-18 age group. The study will be conducted in two phases. The initial phase will assess the efficacy of the training provided to peer mentors. The subsequent phase will examine the impact of peer-led and adult-delivered technology-based education on quality of life, asthma control, asthma knowledge, and self-efficacy in adolescents diagnosed with asthma. The required institutional permission and ethics committee approval was received. The study group of the study will consist of 45 adolescents (intervention group 1 [n=15], intervention group 2 [n=15], and control group [n=15]). Data will be collected by using the descriptive features form, the Adolescent Asthma Self-Efficiacy Questionaire, the Asthma Quality of Life Scale for Children, the Asthma Control Test, the Asthma Knowledge Test.The data will be analyzed using the SPSS 27 program.
The goal of this randomized-controlled clinical study is to investigate the impact of soft tissue phenotype modification following free gingival grafting (FGG) in addition to the non-surgical mechanical therapy of peri-implant mucositis (PM) with keratinized mucosa width (KMW) < 2 mm over a 6-month follow-up period. Therefore, the following questions related to the study are raised: - Does soft tissue modification following free gingival grafting around the implants, in addition to non-surgical mechanical therapy of PM, affect the complete disease resolution? - Does the presence of KMW < 2 mm around the implants exhibit similar outcomes compared to the sites with sufficient KMW (i.e., ≥ 2 mm) for professional mechanical plaque removal? Patients who apply to the Department of Periodontology, Faculty of Dentistry, Gazi University, are systemically healthy, have implant-supported fixed restorations installed at least one year prior to their enrollment, and are diagnosed with PM on these implants will be selected for the study. Patients with KMW < 2 mm at the respective implant sites will be treated with non-surgical mechanical treatment combined with soft tissue augmentation with FGG or non-surgical mechanical treatment alone. As a positive control group, those who apply to the same department, have implants in function as noted during routine annual maintenance appointments, and are diagnosed as healthy will be selected.
Nutrition of school-age children is very important. Children at this age need to eat three main meals and at least one snack every day. Breakfast, among the main meals, is an important component of a healthy diet and is vital for healthy and normal development, especially in children and adolescents. T.R. According to TÜBER prepared by the Ministry of Health, the most frequently skipped meal among school-age children is breakfast. It is necessary to raise awareness in parents and children about regular breakfast consumption and frequency and to instill healthy lifestyle behaviors. It is aimed to regulate breakfast consumption and frequency in parents and children with a web-based training based on PENDER Health Promotion Model (HGM).