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NCT ID: NCT05967806 Recruiting - Renal Disease Clinical Trials

A Study to Identify and Characterise Patients With Chronic Kidney Disease and Proteinuria

Start date: July 31, 2023
Phase:
Study type: Observational

The purpose of the D4325C00007 study is to identify and characterise patients with known or newly diagnosed CKD for possible participation in future renal clinical studies and to obtain an overview on current treatment choices for this patient group in different regions.

NCT ID: NCT05964582 Active, not recruiting - Clinical trials for Respiratory Syncytial Virus Infections

Prospective Surveillance of Respiratory Syncytial Virus Disease in Infants and Toddlers

Start date: July 11, 2023
Phase:
Study type: Observational

The study is a multi-center, multi-national, prospective surveillance study in which the study participants will not receive a study vaccine but will provide a baseline blood sample and be followed for acute respiratory disease during 6 months. The 6-month follow-up will occur for the most part during the Respiratory Syncytial Virus(RSV) season (based on enrollment timing and as per feasibility). A maximum of 1000 children from 6 to < 22 months of age are planned to be enrolled in 5 to 10 countries, 1 to 2 sites per country, targeting approximately 100 participants per country. The purpose of the study is to assess the seroprevalence and incidence of RSV disease during the study period in the targeted countries and sites for a Phase III vaccine study.

NCT ID: NCT05961774 Completed - Low Back Pain Clinical Trials

The Investigation of Underlying Mechanism of Lumbar Multifidus Muscle Activation Deficits

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to investigate mechanism underlying lumbar multifidus muscle (LM) activation deficits in adults with chronic low back pain (CLBP). The main questions it aim to answer is whether motor cortex or muscular level is the underlying mechanism responsible for the LM activation deficits. Participants will: - Undergo cortical excitability measurement using transcranial magnetic stimulation, LM activation measurement using ultrasound imaging, and force measurement using hand-held dynamometer. - Be randomly assigned to either repetitive magnetic stimulation (rTMS) or neuromuscular electrical stimulation (NMES) - Undergo all measurement at post-intervention Researchers will compare within and between groups to see changes in cortical excitability, LM activation, and force.

NCT ID: NCT05955495 Recruiting - Early Feeding Clinical Trials

Length of Stay Between Early Versus Delayed Oral Postoperative Feeding

LOS
Start date: April 19, 2023
Phase: N/A
Study type: Interventional

Length of stay between early versus delayed oral postoperative feeding after gynecologic surgery under General Anesthesia: Randomized Controlled Trial, single center The goal of this Randomized Controlled Trial is to compare Length of stay between early versus delayed oral postoperative feeding after gynecologic surgery under General Anesthesia. The main question[s] it aims to answer are: - Length of stay - Complications Participants will randomized (1:1 block randomization ) into Group A or B. The comparison groups are early and delayed postoperative feeding.

NCT ID: NCT05954793 Recruiting - Clinical trials for Thoracoabdominal Aortic Aneurysm

A PMCF Study in Patients With Thoracoabdominal Aortic Aneurysms Treated With E-nside TAAA Multibranch Stent Graft System (INNER-B-APAC)

Start date: January 1, 2022
Phase:
Study type: Observational [Patient Registry]

The INNER-B-APAC post-market clinical follow-up study is undertaken to demonstrate the safety and clinical performance of the E-nside TAAA Multibranch Stent Graft System used in endovascular treatment of patients with thoracoabdominal aortic aneurysms.

NCT ID: NCT05954286 Recruiting - SARS-CoV-2 Clinical Trials

PROTECT-APT 1: Early Treatment and Post-Exposure Prophylaxis of COVID-19

PROTECT-APT 1
Start date: January 29, 2024
Phase: Phase 2
Study type: Interventional

This study is an adaptive, randomized, double blind, platform trial evaluating promising investigational products (IP) for safety and efficacy as early outpatient treatment and post-exposure prophylaxis for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).

NCT ID: NCT05953987 Completed - Smoking Cessation Clinical Trials

Effects of Aerobic Combined With Diaphragmatic Breathing Exercise in Smokers

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

This study aimed to evaluate the effectiveness of aerobic exercise combined with diaphragmatic breathing exercise on pulmonary function and smoking cessation among smokers.

NCT ID: NCT05952557 Recruiting - Clinical trials for Breast Cancer, Early Breast Cancer

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

CAMBRIA-2
Start date: October 5, 2023
Phase: Phase 3
Study type: Interventional

This is a Phase III open-label study to assess if camizestrant improves outcomes compared to standard adjuvant endocrine therapy for patients with ER+/HER2- early breast cancer with intermediate-high or high risk for disease recurrence who completed definitive locoregional therapy (with or without chemotherapy). The planned duration of treatment in either arm within the study will be 7 years.

NCT ID: NCT05951335 Completed - Stress Clinical Trials

m-Health Supportive Care Transition Program in Improving Post-Discharged Outcomes

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

This intervention study aims to investigate the effects of the m-Health supportive care transition program on response patterns (transition stress and the burden of caregiving) among traumatic brain injury (TBI) caregivers and patients' readmission rate one month after hospital discharge. Specific objectives: 1. Compare the response patterns (transition stress and the burden of caregiving) of TBI caregivers before and after receiving the program within the group. 2. Compare TBI caregivers' response patterns (transition stress and the burden of caregiving) between the control and intervention groups. 3. Compare patients' readmission rates at one month after hospital discharge between the control and intervention groups TBI caregivers are divided into two groups: the intervention group (who receive the transitional care program) and the control group (who receive the standard care program) according to standard operating procedures applicable in the hospital. If there is a comparison group: Researchers will compare [insert groups] to see if [insert effects]

NCT ID: NCT05948995 Recruiting - Clinical trials for Arthroscopic Rotator Cuff Repair

Comparison Between Abduction External Rotation Brace and Arm Sling After Arthroscopic Rotator Cuff

ARCR
Start date: August 1, 2023
Phase: N/A
Study type: Interventional

Comparison between Abduction External Rotation Brace and Arm Sling after Arthroscopic Rotator Cuff : A Randomized Controlled Trial Comparison of primary outcome : range of motion (at pre-operative , post-operative) , pain score , shoulder functional score