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NCT ID: NCT00887120 Completed - HIV Infections Clinical Trials

Dose Reduction of Lopinavir in Children

Start date: April 2007
Phase: Phase 2
Study type: Interventional

To study the pharmacokinetics of low-dose and standard dose, lopinavir/ritonavir in ARV PI naive HIV-1 infected Thai children. To study clinical and immunological efficacy after 48 weeks of lopinavir/ritonavir in PI naïve HIV-1 infected Thai children

NCT ID: NCT00886990 Completed - HIV Infections Clinical Trials

Efficacy and Safety of Single Versus Double Ritonavir-boosted Protease Inhibitor (PI)-Based Antiretroviral Therapy (ART) Regimens

Start date: October 2007
Phase:
Study type: Observational

The virological efficacy will be no different in children treated with single versus double boosted PI second line ART regimens.

NCT ID: NCT00886964 Completed - HIV Infections Clinical Trials

Hepatitis B Vaccination (HBV) in HIV Infected Children

Start date: April 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is : - To evaluate prevalence of protective hepatitis B antibody comparing intradermal (ID) and intramuscular (IM) route in antiHbsAb negative HIV infected children treated with highly active antiretroviral therapy (HAART) - To revaccinate the HBV vaccine in the children who didn't have protective HBV Ab

NCT ID: NCT00886860 Completed - Cervical Ripening Clinical Trials

The Comparison of Efficacy for Cervical Ripening in Labor Induction Between Titrated and Conventional Oral Misoprostol

Start date: May 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the efficacy for cervical ripening in labor induction between titrated and conventional oral misoprostol

NCT ID: NCT00885703 Completed - HIV Infections Clinical Trials

High-Dose Fluconazole for the Treatment of Cryptococcal Meningitis in HIV-Infected Individuals

Start date: April 16, 2010
Phase: Phase 1/Phase 2
Study type: Interventional

Cryptococcal meningitis (CM) is an infection of the membranes covering the brain and spinal cord, caused by the fungus Cryptococcus neoformans. CM most often affects people with compromised immune systems, like those with advanced HIV infection. This study explored the safety, tolerability, and therapeutic effect of a new treatment regimen with high-dose fluconazole for management of CM in HIV-infected patients.

NCT ID: NCT00883779 Completed - Clinical trials for Non-Squamous Non-Small Cell Lung Cancer

A Study of Tarceva (Erlotinib) or Placebo in Combination With Platinum-Based Therapy as First Line Treatment in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer

Start date: April 2009
Phase: Phase 3
Study type: Interventional

This 2 arm study will compare the efficacy and safety of sequential treatment with Tarceva or placebo, plus platinum-based therapy, as first line treatment in patients with advanced or recurrent non-small cell lung cancer. Patients will be randomized to receive gemcitabine (1250mg/m2 iv) on days 1 and 8, and cisplatin (75mg/m2) or carboplatin (5xAUC)on day 1, followed by Tarceva 150mg/day or placebo from day 15 to day 28 of each 4 week cycle for a total of 6 cycles,then followed by Tarceva or placebo monotherapy.The anticipated time on study treatment is until disease progression, and the target sample size is 100-500 individuals.

NCT ID: NCT00883441 Completed - DENGUE Clinical Trials

Implementation Research of New Dengue Vector Control Tools

Start date: July 2006
Phase: N/A
Study type: Interventional

This project will provide new insights concerning how to reduce dengue transmission by means of cost-effective and sustainable implementation strategies of vector control methods. The research will assess key strategies which deliver new vector control tools with respect to their cost-effectiveness, acceptability and sustainability in contrasting environments.

NCT ID: NCT00882453 Completed - Multiple Sclerosis Clinical Trials

Physical Activity and Fatigue in Early Multiple Sclerosis (MS)

BEGIN
Start date: August 2006
Phase: N/A
Study type: Observational

The purpose of this observational study is to obtain a survey on physical activity in patients who for the first time have experienced symptoms which indicate a high risk for developing multiple sclerosis (MS) and in patients with recently diagnosed MS, and to obtain information on factors potentially influencing the patients' level of activity.

NCT ID: NCT00879333 Completed - Clinical trials for Advanced Gastric Cancer

Safety and Efficacy of RAD001 (Everolimus) Monotherapy Plus Best Supportive Care in Patients With Advanced Gastric Cancer (AGC)

GRANITE-1
Start date: July 2009
Phase: Phase 3
Study type: Interventional

This study is designed to assess the safety and efficacy of RAD001 monotherapy in patients with advanced gastric cancer which has progressed after one or two lines of prior chemotherapy.

NCT ID: NCT00877175 Completed - Preterm Infants Clinical Trials

Comparison of Instillation and Packing in Mydriasis for Premature Infants

Start date: March 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the mydriatic effect of 2.5% phenylephrine and 1% tropicamide by conventional instillation and lower conjunctival fornix packing in premature infants.