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NCT ID: NCT01203605 Completed - Non-cardiac Surgery Clinical Trials

European Surgical Outcomes Study

EuSOS
Start date: April 2011
Phase: N/A
Study type: Observational

The European Surgical Outcomes Study (EuSOS) is a multi-centre, international cohort study of peri-operative care and clinical outcomes for patients undergoing non-cardiac surgery. Participating centres throughout Europe will contribute routine clinical data describing all eligible patients who undergo surgery from 4th April 2011 to 11th April 2011. Patients will then be followed until hospital discharge (or for a maximum of 60 days) for duration of hospital stay and hospital mortality. Routine clinical data will also be collected for those patients admitted to critical care at any stage after surgery but during the same hospital admission. Specific objectives are to describe clinical outcomes and standards of peri-operative care for patients undergoing non-cardiac surgery in Europe.

NCT ID: NCT01203124 Completed - Healthy Volunteers Clinical Trials

A Study to Investigate the Impact of Dose and Dosing Frequency of AZD8848 on the Response on Biomarkers

Start date: November 2010
Phase: Phase 1
Study type: Interventional

The study will investigate how the dose of AZD8848 and the dosing frequency will affect the immunological/inflammatory response by measuring the production of biomarkers in blood and nasal lavage.

NCT ID: NCT01201356 Completed - Clinical trials for Relapsing Forms of Multiple Sclerosis

Long-term Safety and Tolerability of 0.5 mg Fingolimod in Patients With Relapsing Forms of Multiple Sclerosis

Start date: September 13, 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study was to collect long-term safety and tolerability, long-term efficacy, and health outcome data in all patients currently ongoing in the fingolimod multiple sclerosis clinical development program. This study combined all currently ongoing Phase II and III fingolimod extension studies as well as ongoing and newly planned studies into one single long-term extension protocol that provided patients with continuous treatment until fingolimod was registered, commercially available, and reimbursed in the respective countries.

NCT ID: NCT01200524 Completed - Nerve Pain Clinical Trials

A Study to Investigate the Analgesic Efficacy of AZD2423 Compared With Placebo After 28 Days Treatment in Patients With Posttraumatic Neuralgia..

Start date: October 2010
Phase: Phase 2
Study type: Interventional

A study to investigate the analgesic efficacy of AZD2423 compared with placebo after 28 days treatment in patients with posttraumatic neuralgia.

NCT ID: NCT01200394 Completed - Clinical trials for Diabetic Nephropathies

A Phase 2, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of PF-00489791 In Patients With Type 2 Diabetes And Overt Nephropathy

Start date: December 2010
Phase: Phase 2
Study type: Interventional

PF-00489791 is an inhibitor of phosphodiesterase type 5. Our hypothesis is that PF-00489791 will enhance the relaxation of blood vessels within the kidney and so reduce blood pressure, improving renal function.

NCT ID: NCT01200186 Completed - Clinical trials for Contraceptives, Oral

Non-interventional Study on Oral Contraception Not Containing Ethinylestradiol (EE) to Assess Continuation Rates and Satisfaction

Start date: October 2010
Phase: Phase 4
Study type: Observational

Prospective, non-interventional, multi-center study. Each subject will be followed for up to twelve months during the treatment with oral hormonal contraceptives(Qlaira ® or a Progestin Only Pill). For each subject demographic data and medical history will be documented at Visit 1: (Baseline). Bleeding profile, subjective assessment of study treatment (satisfaction and wellbeing) and adverse events including unintended pregnancies will be documented at Visit 2 (Month 3-5) and Visit 3 (Month 6-12). Data audit/monitoring will be done.

NCT ID: NCT01199458 Completed - Clinical trials for Lower Esophageal Sphincter

The Effect of an Opioid on the Lower Esophageal Sphincter During Anesthesia Induction

Start date: September 2010
Phase: Phase 4
Study type: Interventional

This study evaluates the effects of adding an opioid (alfentanil) during anesthesia induction with respect to the barrierpressure in the esophagogastric junction. The secondary aim was to investigate whether the effect of cricoid pressure influences the barrierpressure.

NCT ID: NCT01199341 Completed - Pharmakokinetic Clinical Trials

A Drug-Drug Interaction Study to Study the Effect of AZD1981 on Warfarin

Start date: October 2010
Phase: Phase 1
Study type: Interventional

The primary purpose of this study is to determine whether the treatment with AZD1981 affect the exposure of Warfarin.

NCT ID: NCT01198847 Completed - Obesity Clinical Trials

Early Stockholm Obesity Prevention Program

EarlySTOPP
Start date: January 2010
Phase: N/A
Study type: Interventional

To study whether a targeted intervention can prevent the development of overweight and obesity among pre-school children in families with either one obese or two overweight parents.

NCT ID: NCT01197950 Completed - Labour Pain Clinical Trials

Acupuncture With Manual and Electrical Stimulation to Reduce Labour Pain

Start date: October 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of manual acupuncture and electro-acupuncture on labour pain.