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NCT ID: NCT01721772 Completed - Melanoma Clinical Trials

Study of Nivolumab (BMS-936558) Compared With Dacarbazine in Untreated, Unresectable, or Metastatic Melanoma

CheckMate 066
Start date: January 18, 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the clinical benefit, as measured by overall survival, of nivolumab with that of. dacarbazine in patients with previously untreated, unresectable, or metastatic melanoma

NCT ID: NCT01721161 Completed - Clinical trials for Acute Optic Neuritis

215ON201 BIIB033 In Acute Optic Neuritis (AON)

RENEW
Start date: December 2012
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to evaluate the efficacy of BIIB033 in subjects with their first episode of unilateral Acute Optic Neuritis (AON). The secondary objective of this study in this study population is to assess the safety, tolerability, and pharmacokinetics (PK) of BIIB033.

NCT ID: NCT01720771 Completed - Dental Caries Clinical Trials

Preventive Effect of a Probiotic Tablet on Oral Health in Preschool Children

Start date: February 2013
Phase: N/A
Study type: Interventional

The aim of the prospective project is to investigate effect of daily probiotic supplements on dental caries development in preschool children living in a low socioeconomic immigrant area in souithern Sweden. The study design is a randomised controlled trial with two parallell arms. The intervention is one probiotic tablet or placebo once daily. The null hypothesis is that the caries experience and increment will not differ betwwen the two groups.

NCT ID: NCT01720524 Completed - Clinical trials for Pulmonary Hypertension, Familial Persistent, of the Newborn

A Study To Evaluate Safety And Efficacy Of IV Sildenafil In The Treatment Of Neonates With Persistent Pulmonary Hypertension Of The Newborn

Start date: August 5, 2013
Phase: Phase 3
Study type: Interventional

This study will evaluate whether IV sildenafil can reduce the time on inhaled nitric oxide treatment and reduce the failure rate of available treatments for persistent pulmonary hypertension of the newborn.

NCT ID: NCT01720251 Completed - Allergic Rhinitis Clinical Trials

Efficacy Study of a Preseasonal Treatment With AllerT in Subjects With Birch Pollen Allergy

Start date: October 2012
Phase: Phase 2
Study type: Interventional

The main objective of the trial is to demonstrate the efficacy of a two months pre-seasonal treatment with AllerT 100 µg maintenance dose in reducing symptoms of allergic rhinoconjunctivitis during the following birch pollen season

NCT ID: NCT01719159 Completed - Clinical trials for Progressive Multiple Sclerosis

Intrathecal Therapy With Monoclonal Antibodies in Progressive Multiple Sclerosis

ITT-PMS
Start date: November 2009
Phase: Phase 2
Study type: Interventional

This is a is a small scale open phase two interventional study to assess long-term stabilising effects of on neurological symptoms by regular intrathecal administered monoclonal antibodies in progressive multiple sclerosis.

NCT ID: NCT01718483 Completed - Clinical trials for Binge Eating Disorder

SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder

Start date: November 26, 2012
Phase: Phase 3
Study type: Interventional

The primary objective of the study is to demonstrate the efficacy of SPD489 compared with placebo in adults (18 55 years of age inclusive) with moderate to severe Binge Eating Disorder at Visit 8 (Weeks 11 and 12) as measured by the number of binge days (defined as days during which at least 1 binge episode occurs) per week as assessed by clinical interview based on subject diary

NCT ID: NCT01718431 Completed - Metabolic Syndrome Clinical Trials

Prebiotics as a Means to Modulate Gut Fermentation, Metabolism, Appetite and Cognition

Start date: October 2010
Phase: Phase 0
Study type: Interventional

This study aims at investigating the impact of colonic fermentation of intrinsic indigestible carbohydrates in cereal whole kernels after three days consumption, on metabolic variables and cognition. The study is performed in healthy, normal to slightly over-weight test subjects.

NCT ID: NCT01718418 Completed - Obesity Clinical Trials

Role of Colonic Events on Metabolism and Appetite Control: A Synbiotic Approach

Start date: September 2012
Phase: Phase 0
Study type: Interventional

The purpose of the study is to evaluate food factors related to colonically derived regulation of glucose metabolism (and related parameters) and satiety using a semi-acute meal study in healthy subjects as experimental model.

NCT ID: NCT01716390 Completed - Clinical trials for Hypercholesterolemia

Lipid-lowering Effect of Plant Stanol Drink

Start date: January 2011
Phase: N/A
Study type: Interventional

To determine the effect of investigational products on serum LDL cholesterol.