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NCT ID: NCT00057616 Completed - Melanoma Clinical Trials

Study to Compare the Efficacy and Safety of CC-5013 vs. Placebo in Subjects With Metastatic Malignant Melanoma.

Start date: October 1, 2002
Phase: Phase 3
Study type: Interventional

Subjects are randomized to one of two treatment arms. All subjects are screened for eligibility within 28 days prior to randomization. The study consists of a treatment phase and a follow-up phase. Subjects are treated in repeating 4 week cycles.

NCT ID: NCT00057317 Completed - Diabetes Clinical Trials

Study of Ro 205-2349 in Patients With Type 2 Diabetes Mellitus

Start date: December 2001
Phase: Phase 2
Study type: Interventional

The objective of the study is to determine the dose(s) of Ro 205-2349 which, when compared to placebo, are efficacious, safe and tolerable in improving glycemic control in patients with type 2 diabetes. Doses of 5 to 20 mg/day will be studied.

NCT ID: NCT00056576 Completed - Clinical trials for Epilepsy, Complex Partial

Dose Response Study of Zonegran in Patients With Newly Diagnosed Epilepsy

Start date: February 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether zonisamide alone is effective as a treatment for epilepsy in newly diagnosed cases.

NCT ID: NCT00056407 Completed - Neoplasms, Prostate Clinical Trials

"REDUCE" - A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased Risk

REDUCE
Start date: March 2003
Phase: Phase 3
Study type: Interventional

This 4-year study will compare how safe and effective an oral investigational medicine is (compared to placebo) in preventing the development of prostate cancer in men that are defined by the study entrance criteria as being at an increased risk for prostate cancer. Study visits to the clinic will occur every 6 months for up to 4 years (10 clinic visits), and a prostate biopsy will be performed at 2 and 4 years of treatment.

NCT ID: NCT00049998 Completed - Clinical trials for Non-Small-Cell Lung Cancer

Oral Topotecan Versus Intravenous Docetaxel In Pretreated, Advanced Non-Small Cell Lung Cancer

Start date: October 2001
Phase: Phase 3
Study type: Interventional

The purpose of this study is to collect information on how effective and how well tolerated an oral investigational drug is compared to a standard intravenous drug in patients with pretreated, advanced non-small lung cancer (NSCLC).

NCT ID: NCT00044421 Completed - Diabetes Mellitus Clinical Trials

Treatment of Peripheral Neuropathy in Patients With Diabetes

Start date: July 2002
Phase: Phase 3
Study type: Interventional

The purpose of this protocol is to determine if an investigational drug is effective in treating nerve malfunction in diabetes.

NCT ID: NCT00044408 Completed - Clinical trials for Diabetic Neuropathies

Treatment for Symptomatic Peripheral Neuropathy in Patients With Diabetes

Start date: July 2002
Phase: Phase 3
Study type: Interventional

The purpose of this protocol is to determine if an investigational drug known as LY333531 is effective in treating nerve malfunction in diabetes.

NCT ID: NCT00044278 Completed - Epilepsy Clinical Trials

Pediatric Epilepsy Study in Subjects 1-24 Months

Start date: September 2000
Phase: Phase 2
Study type: Interventional

This study will evaluate the long-term safety of LAMICTAL(lamotrigine)in subjects with partial seizures previously enrolled in protocol LAM20006 and in subjects 1-24 months of age who have never received LAMICTAL(LAMICTAL-naive). For LAMICTAL-naive subjects, LAMICTAL will be added to the subject's current epilepsy medications.

NCT ID: NCT00043927 Completed - Clinical trials for Small Cell Lung Cancer

Extensive Small Cell Lung Cancer Treatment Using An Investigational Drug Plus Chemotherapy In Chemotherapy-Naive Adults

Start date: April 2001
Phase: Phase 3
Study type: Interventional

This study will gather and compare data about the effectiveness and safety of two different treatments for extensive Small Cell Lung Cancer (SCLC) in patients who have not received previous chemotherapy. One treatment will use an investigational drug in combination with an FDA approved chemotherapy. The other treatment will use a combination of two FDA approved chemotherapy drugs.

NCT ID: NCT00043875 Completed - Epilepsy Clinical Trials

Pediatric Epilepsy Trial in Subjects 1-24 Months

Start date: May 2000
Phase: Phase 2
Study type: Interventional

This study is being conducted to evaluate the effectiveness and safety of LAMICTAL added to the current therapy of pediatric patients age 1-24 months old with partial seizures. The medication used in this study has been approved by FDA for the adjunctive treatment of partial seizures in patients 2 years and older.