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NCT ID: NCT03901352 Completed - Clinical trials for Central Neuropathic Pain

Study of Mirogabalin for Central Neuropathic Pain

Start date: March 12, 2019
Phase: Phase 3
Study type: Interventional

Investigate the efficacy and safety of mirogabalin in participants with central neuropathic pain in comparison to placebo

NCT ID: NCT03900715 Completed - Clinical trials for Myelodysplastic Syndromes

An Efficacy and Safety Study of Luspatercept (ACE-536) for the Treatment of Anemia Due to IPSS-R Very Low, Low or Intermediate Risk Myelodysplastic Syndromes (MDS) in Japanese Subjects Who Are Not Requiring Red Blood Cell Transfusion

Start date: May 20, 2019
Phase: Phase 2
Study type: Interventional

The study will be conducted in compliance with the International Council for Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good Clinical Practice (GCP) and applicable regulatory requirements. This is a Phase 2, multicenter, single-arm study to evaluate the efficacy, safety and Pharmacokinetics (PK) of luspatercept (ACE-536) for the treatment of anemia due to International prognostic scoring system-Revised (IPSS-R) very low, low or intermediate risk Myelodysplastic syndromes (MDS)in Japanese subjects who are not requiring Red blood cell (RBC) transfusion. The study is divided into the Screening Period, a Treatment Period and a Post-Treatment Follow up Period.

NCT ID: NCT03900377 Completed - Clinical trials for Lymphoma, B-cell, Diffuse

Phase I/II Study of SyB L-0501RI in Combination With Rituximab to Treat Lymphoma

Start date: April 1, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

For SyB L-0501RI administered by an intravenous rapid infusion in combination with rituximab, the safety will be investigated in previously untreated patients with low-grade B-cell non-Hodgkin's lymphoma (Lg-B-NHL) or mantle cell lymphoma (MCL), and the safety and tolerability will be investigated in patients with recurrent/refractory diffuse large B-cell lymphoma (DLBCL).

NCT ID: NCT03898791 Completed - Clinical trials for Small Cell Lung Cancer

A Study of LY3295668 Erbumine in Participants With Extensive-stage Small-Cell Lung Cancer

Start date: July 16, 2019
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the recommended phase 2 dose of LY3295668 erbumine in participants with platinum-sensitive, extensive-stage small-cell lung cancer.

NCT ID: NCT03896581 Completed - Psoriatic Arthritis Clinical Trials

A Study to Evaluate the Efficacy and Safety of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis

BE COMPLETE
Start date: March 28, 2019
Phase: Phase 3
Study type: Interventional

This is a study to demonstrate the clinical efficacy, safety and tolerability of bimekizumab administered subcutaneously (sc) compared with placebo in the treatment of tumor necrosis factor alpha-inadequate responders (TNFα-IR) subjects with active Psoriatic Arthritis (PsA).

NCT ID: NCT03895502 Completed - Neoplasms Clinical Trials

Optimal Duration of Anticoagulation Therapy for Isolated Distal Deep Vein Thrombosis in Patients With Cancer Study

ONCO DVT
Start date: May 27, 2019
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the optimal duration of anticoagulation therapy (3 months versus 12 months) with direct oral anticoagulant (edoxaban) for isolated distal deep vein thrombosis.

NCT ID: NCT03895372 Completed - Psoriasis Clinical Trials

A Study to Evaluate Safety and Efficacy of PF-06826647 For Moderate To Severe Plaque Psoriasis

Start date: June 27, 2019
Phase: Phase 2
Study type: Interventional

This multicenter study is being conducted to provide additional PF-06826647 safety and tolerability data, and to further explore the clinical efficacy of PF-06826647 in the treatment of moderate to severe plaque psoriasis. Additionally, the study is intended to enable selection of oral dose and dosing regimen for the future clinical development of PF-06826647.

NCT ID: NCT03895203 Completed - Psoriatic Arthritis Clinical Trials

A Study to Test the Efficacy and Safety of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis

BE OPTIMAL
Start date: April 3, 2019
Phase: Phase 3
Study type: Interventional

This is a study to demonstrate the clinical efficacy, safety and tolerability of bimekizumab administered subcutaneously (sc) compared with placebo in the treatment of subjects with active Psoriatic Arthritis (PsA).

NCT ID: NCT03894956 Completed - Clinical trials for Hidradenitis Suppurativa (HS)

Observational Study Evaluating Long-Term Safety and Effectiveness of Humira in Patients With Hidradenitis Suppurativa

Start date: May 2, 2019
Phase:
Study type: Observational

The objective of this study is to evaluate the long-term safety and effectiveness of Humira in patients with Hidradenitis Suppurativa (HS) in real-world clinical practice in Japan.

NCT ID: NCT03891758 Completed - Tetanus Clinical Trials

Confirmatory Study of BK1310 in Healthy Infants

Start date: April 1, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate immunogenicity of BK1310 for all antigens (anti-PRP, diphtheria toxin, pertussis, tetanus toxin, and polio virus), after 3 times of injection, when compared noninferiority with co-administration of ActHIB® and Tetrabik, as well as efficacy and safety, in healthy infants.