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NCT ID: NCT03175367 Completed - Clinical trials for Hypercholesterolemia

Study of Evinacumab (REGN1500) in Participants With Persistent Hypercholesterolemia

Start date: November 10, 2017
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to evaluate the reduction of LDL-C by evinacumab in comparison to placebo after 16 weeks in patients with primary hypercholesterolemia (HeFH, or non-HeFH with a history of clinical ASCVD) with persistent hypercholesterolemia despite receiving maximally-tolerated LMT. Persistent hypercholesterolemia is defined as LDL-C ≥70 mg/dL (1.81 mmol/L) for those patients with clinical ASCVD and LDL-C ≥100 mg/dL (2.59 mmol/L) for those patients without clinical ASCVD.

NCT ID: NCT03175198 Completed - Atrial Fibrillation Clinical Trials

Japanese Pradaxa PMS, Long Term

Start date: July 5, 2017
Phase:
Study type: Observational

The study objective is to confirm appropriate use and safety profile of Prazaxa® Capsules in real-world setting after the availability of idarucizumab

NCT ID: NCT03175029 Completed - Overactive Bladder Clinical Trials

Exploratory Study of TAC-302 in Detrusor Underactivity Patients With Overactive Bladder.

Start date: August 1, 2017
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of TAC-302 in detrusor underactivity patients with overactive bladder.

NCT ID: NCT03172819 Completed - Clinical trials for Advanced Solid Tumor

Special Combination of OBP-301 and Pembrolizumab

Start date: October 1, 2017
Phase: Phase 1
Study type: Interventional

This is multicenter, open-label Phase I study to exploratively evaluate the efficacy and safety of OBP-301 in combination with Pembrolizumab in patients with advanced solid tumors.

NCT ID: NCT03172702 Completed - Hyperkalemia Clinical Trials

Open-label Safety of Sodium Zirconium Cyclosilicate for up to 12 Months in Japanese Subjects With Hyperkalemia

Start date: September 4, 2017
Phase: Phase 3
Study type: Interventional

The Open-Label Maintenance Study contains an Correction Phase, in which subjects will be dosed with ZS 10 g three times daily (tid) for 24 to 72 hours, followed by a 12-month long-term Maintenance Phase.

NCT ID: NCT03169972 Completed - Hemophilia A Clinical Trials

ADYNOVATE Drug Use-Results Survey

Start date: April 12, 2017
Phase:
Study type: Observational

The purpose of this survey is to understand the following items in the actual clinical use of ADYNOVATE in patients: 1. Unexpected adverse drug reactions 2. Occurrence of adverse drug reactions in the actual clinical use 3. Factors that may affect safety and efficacy 4. Occurrence of Factor VIII inhibitor development in patients with coagulation factor VIII deficiency (hereinafter hemophilia A) 5. Safety and efficacy for hemophilia A patients who received routine prophylactic therapy and on-demand therapy

NCT ID: NCT03169361 Completed - Clinical trials for Relapsed/Refractory Multiple Myeloma

NINLARO Capsules Drug Use-Results Survey (All-Case Surveillance) "Relapsed/Refractory Multiple Myeloma"

Start date: May 24, 2017
Phase:
Study type: Observational

The purpose of this study is to evaluate the safety of NINLARO in participants with relapsed/refractory multiple myeloma in daily clinical practice.

NCT ID: NCT03165422 Completed - Melanoma Clinical Trials

A Real-World Study of Ipilimumab Treatment After Nivolumab Treatment in Melanoma in Japan

Start date: March 1, 2017
Phase:
Study type: Observational

This is a medical chart review of ipilimumab treatment after nivolumab treatment in melanoma in Japan

NCT ID: NCT03163355 Completed - Swallowing Disorder Clinical Trials

Comparison of Pureed Rice Using a Gelling Agent and Standard Pureed Rice

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

The texture of the pureed diet is likely to be most useful factor predictive of the prevention of aspiration pneumonia. However, it has not been previously reported what kinds of texture of the pureed diet can prevent aspiration pneumonia. Using endoscopic swallowing evaluation, we attempt to compare two kinds of the pureed diets to choose the better texture of pureed diets in elderly patients with severe dysphagia.

NCT ID: NCT03161145 Completed - Clinical trials for Renal Cell Carcinoma

A Study to Observe the Treatment Patterns and Outcomes of Patients in Japan With Kidney Cancer That is Unable to be Removed by Surgery or That Has Spread

Start date: December 9, 2016
Phase: N/A
Study type: Observational

A medical review chart study in Japan to describe the treatment patterns and outcomes of patients with kidney cancer that is unable to be removed by surgery or that has spread. The clinical data is to be abstracted using electronic data capture (eDC) from patient medical records in Japan.