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NCT ID: NCT01032915 Terminated - Clinical trials for Non-infectious Uveitis

Safety and Efficacy of AIN457 in Patients With Quiescent Non-infectious Uveitis

ENDURE
Start date: February 2010
Phase: Phase 3
Study type: Interventional

This study will assess the safety and efficacy of AIN457 as adjunctive therapy for the treatment of intermediate uveitis, posterior uveitis, or panuveitis requiring systemic immunosuppression.

NCT ID: NCT01032291 Terminated - Colorectal Cancer Clinical Trials

A Study to Assess the Efficacy and Safety of Lenalidomide in Combination With Cetuximab in Pre-treated Patients With KRAS Mutant Colorectal Cancer

Start date: December 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether lenalidomide in combination with cetuximab is safe and effective in patients with KRAS mutant colorectal cancer.

NCT ID: NCT01023438 Terminated - Clinical trials for Chronic Heart Failure

Strategies to Improve Prescribing in Heart Failure Patients

Start date: January 2010
Phase: N/A
Study type: Interventional

The purpose of the study is to assess whether primary care physicians may uptitrate recommended drug therapies in stable heart failure patients if educational material and specialist support including phone or mail consultation are provided

NCT ID: NCT01023269 Terminated - Clinical trials for Urinary Incontinence

Efficacy Study of Pudendal Neuromodulation for the Treatment of Neurogenic Overactive Bladder

ACCEPTANCE
Start date: December 2009
Phase: N/A
Study type: Interventional

The study is designed to demonstrate that treatment with low level stimulation of the bladder muscles reduces symptoms of urinary incontinence in comparison with no stimulation.

NCT ID: NCT01021423 Terminated - Clinical trials for Non-Hodgkin's Lymphoma

A Study to Evaluate the Efficacy of Lenalidomide as Maintenance Therapy After Completion of First-line Combination Chemotherapy in Patients With Mantle Cell Lymphoma (MCL).

RENEW
Start date: April 1, 2010
Phase: Phase 3
Study type: Interventional

A study to evaluate the efficacy of lenalidomide as maintenance therapy after completion of first-line combination chemotherapy in patients with mantle cell lymphoma (MCL) who are not candidates for transplantation and have achieved partial response (PR) or complete response (CR). This study was prematurely terminated by the sponsor in light of new unpublished data that rendered the current design of the study no longer clinically relevant. A study design with the control arm of no active treatment was no longer appropriate. The termination of the trial was not based on any safety concerns in the study.

NCT ID: NCT01018953 Terminated - Carcinoid Syndrome Clinical Trials

Study to Assess the Efficacy and Safety of Different Doses of BIM 23A760 in Patients With Carcinoid Syndrome

CAMPANULA
Start date: February 2010
Phase: Phase 2
Study type: Interventional

The purpose of the protocol is to assess the efficacy and safety of BIM 23A760 on patient's overall satisfaction in terms of symptom relief (diarrhoea and/or flushes) in patients with carcinoid syndrome after 24 weeks of treatment.

NCT ID: NCT01013623 Terminated - Clinical trials for Stage IV Resectable Melanoma

Stage IV Surgery Versus Best Medical Therapy

STG4SURG
Start date: November 2009
Phase: Phase 3
Study type: Interventional

This study will establish the role of surgical versus nonsurgical approaches in patients whose melanoma has spread to distant sites. Results will help clinicians develop a standardized initial approach that prolongs survival and optimizes quality of life. Results also will indicate whether Bacillus Calmette-Guerin (BCG) postoperative immunotherapy significantly improves the outcome of patients treated with surgery.

NCT ID: NCT01011439 Terminated - Thymic Carcinoma Clinical Trials

Phase II Study Of Oral PHA-848125AC In Patients With Thymic Carcinoma

Start date: February 22, 2010
Phase: Phase 2
Study type: Interventional

The intent of the study is to assess the antitumor activity of PHA-848125AC as second-line treatment in patients with recurrent or metastatic, unresectable thymic carcinoma previously treated with chemotherapy.

NCT ID: NCT01009957 Terminated - Clinical trials for Polycystic Kidney Diseases

Everolimus on CKD Progression in ADPKD Patients

Start date: June 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The study will evaluate whether the administration of everolimus (1.5 mg/day) can slow down the progression of CKD in ADPKD patients.

NCT ID: NCT01009593 Terminated - Neoplasms Clinical Trials

Efficacy and Tolerability of ABT-869 Versus Sorafenib in Advanced Hepatocellular Carcinoma (HCC)

Start date: January 2010
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to assess the overall survival (OS) of oral linifanib given as monotherapy once daily (QD) compared to sorafenib given twice daily (BID) per standard of care in subjects with advanced or metastatic HCC.