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NCT ID: NCT01277523 Completed - Asthma Clinical Trials

Efficacy and Safety of 2 Doses of Tiotropium Respimat Compared to Placebo in Adolescents With Severe Persistent Asthma

Start date: January 2011
Phase: Phase 3
Study type: Interventional

The overall purpose of the trial is to evaluate efficacy and safety of tiotropium inhalation solution delivered via Respimat® inhaler (2.5 mcg and 5 mcg once daily) over 12 weeks, compared to placebo, as add-on controller therapy on top of usual care in adolescents (12 to 17 years old) with severe persistent asthma. The primary objective of the trial is to demonstrate superiority of tiotropium (5 mcg and possibly 2.5 mcg once daily in the evening) over placebo with regard to the primary pulmonary function endpoint after 12 weeks of treatment. Secondary objectives are to evaluate efficacy of tiotropium with regard to other endpoints, and to evaluate the safety of tiotropium, compared to placebo, as add-on controller therapy on top of usual care in this patient population.

NCT ID: NCT01277107 Completed - Insomnia Clinical Trials

A Polysomnographic Study to Compare the Efficacy of Gastric Retentive Zaleplon Accordion Pill to Placebo in Subjects With Insomnia

Start date: January 2011
Phase: Phase 2
Study type: Interventional

This is a multi center, double blind placebo controlled, two-way crossover study in patients with Insomnia suffering from difficulty in falling asleep and staying asleep. This study intends to assess the efficacy of Zaleplon AP in improving sleep parameters, comparing to placebo.

NCT ID: NCT01274949 Completed - Clinical trials for Erectile Dysfunction

The Effect of Low Intensity Shockwave Therapy for ED in Post Radical Prostatectomy Patients Who Didn't Respond to PDE5i

LI-ESWT
Start date: February 2010
Phase: Phase 3
Study type: Interventional

Low Intensity Shock Wave Therapy (LI-ESWT) was shown to have a beneficial effect on ED patients responding to PDE5i's. This study aimed to determine the capability of LI-ESWT to affect patients who underwent radical prostatectomy who did not respond to PDE5 inhibitor therapy.

NCT ID: NCT01274923 Recruiting - Clinical trials for Erectile Dysfunction

Double Blind Placebo Controlled Study on the Effect of Extracorporal Shock Wave Therapy on Erectile Dysfunction in PDE5i Responders

LI-ESWT
Start date: August 2010
Phase: Phase 3
Study type: Interventional

This study aims to evaluate the effect of shockwave therapy on erectile dysfunction on patients responding to PDE5i therapy in a sham controlled randomized double blind manner.

NCT ID: NCT01274910 Recruiting - Clinical trials for Rheumatoid Arthritis

Effect of Fish Oil on Surgery Pain After Knee Replacement Patients: Randomized, Prospective, Double Blind, Placebo Control Trial

EFOPaKR-01
Start date: January 2011
Phase: N/A
Study type: Interventional

This is a single-center, prospective, randomized, double blind, placebo control study. The aim of this study is to assess the effect of fish oil capsules on pain intensity and postoperative analgesics consumption in patients after knee replacement surgery. The study population will be adult are referred for knee replacement surgery due to osteoarthritis of the knee.

NCT ID: NCT01274299 Recruiting - Infant Development Clinical Trials

Measurements of Facial Dimensions in Infants and Toddlers 0-4 Years of Age

Start date: November 2010
Phase: N/A
Study type: Observational

Anthropometric data of infants' face will be obtained using special 3D scanners and software.

NCT ID: NCT01274247 Terminated - Clinical trials for Neonatal Latch Difficulties

Use of Topical Benzocaine for Analgesia in Lingual Frenotomy of the Newborn

Start date: February 2011
Phase: Phase 1/Phase 2
Study type: Interventional

Frenotomy of tongue-tie is commonly performed to resolve breastfeeding difficulties, eg maternal nipple pain and infant's latching difficulties. The procedure carries minor discomfort for the infants. It is not known whether the use of topical benzocaine, a very bitter tasting material' applied to the tongue-tie would decrease the length of cry. We will measure the duration of crying in infants treated with topical benzocaine to the duration in those not treated with the mediation.

NCT ID: NCT01274208 Recruiting - Hepatitis C Clinical Trials

Examining the Immune Response in Patients With Gaucher Disease and Hepatitis C

Start date: January 2011
Phase: N/A
Study type: Observational

Study objectives: - Investigate the anti-HCV response in patients with Gaucher disease(GD) - Define the potential role of high levels of Glucocerebroside in the immune system Study hypothesis: High levels of Glucocerebroside can be used as a tool in the antiviral treatment of hepatitis C by potentiating the immune response of natural killer T cells and dendritic cells

NCT ID: NCT01274156 Completed - Clinical trials for Erectile Dysfunction

Double Blind Placebo Controlled Study on the Effect of Extracorporal Shock Wave Therapy on Erectile Dysfunction

LI-ESWT
Start date: August 2010
Phase: Phase 3
Study type: Interventional

This study aims to evaluate the effect of shockwave therapy on erectile dysfunction on patients responding to PDE5i therapy in a sham controlled randomized double blind manner.

NCT ID: NCT01273779 Suspended - Severe Sepsis Clinical Trials

Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis

OASIS
Start date: June 2011
Phase: Phase 2/Phase 3
Study type: Interventional

Study will evaluate the safety and potential benefit of talactoferrin (recombinant human lactoferrin) as an addition to the standard care for severe sepsis.