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NCT ID: NCT01923220 Not yet recruiting - Breast Cancer Clinical Trials

Safety and Efficacy of HO/02/02 20µg vs. SoC (Aloe Vera) to Reduce Radiation Dermatitis

ARD
Start date: September 2013
Phase: Phase 0
Study type: Interventional

This is a single-center, open-label, randomized, prospective study evaluating the safety and efficacy of HO/02/02 20µg topically applied daily for 15 minutes (with gauze) on treatment fields vs. standard of care (SoC), Aloe Vera treatment

NCT ID: NCT01922453 Not yet recruiting - Breech Presentation Clinical Trials

Music and Sounds for ECV

RITMO
Start date: September 2013
Phase: N/A
Study type: Interventional

This international study is looking to see if the addition of music and sound on the maternal abdomen encourages fetal position change from breech to vertex in near term women.

NCT ID: NCT01918163 Not yet recruiting - Clinical trials for Male Infertility With Severe Oligo-terato-asteno-spermia

Anti-oxidative Influence From Pomegranate Tablets on Male Sperm Quality in Couples Undergo Infertility Treatments Due to Male Infertility.

Pomegranate
Start date: September 2013
Phase: Phase 3
Study type: Interventional

Some animal studies revealed that the pomegranate juice may improve sperm quality in terms of concentration, motility and morphology, as well as in fertilization rate. Minor data is available regarding the influence on male sperm.

NCT ID: NCT01917500 Not yet recruiting - Clinical trials for Heart or Vascular Disease

Feasibility Study of Non-invasive and Continuous Measurement of Blood Pressure and Cardiac Output: Comparison to Non-invasive and Non-continuous Measurements

Start date: August 2013
Phase: N/A
Study type: Observational

The objectives of this clinical trial is to validate a S/W application to compare the calculations of Hemodynamic parameters like Continuous blood pressure (BP) and Continuous cardiac output (CO). This Hemodynamic parameters are computed from Pulse Oximeter (PhotoPlethysmograph or PPG) signal with results obtained by NIBP intermittent measurements and Echocardiography. The first phase of the study will be done on 10 patients of the Cardiology dept.- Cardiac ICU, that have routine measurements of BP and CO using Echocardiography. The HeartBeat system combines an FDA/CE approved watch-like Pulse Oximeter for acquiring the data and a Smartphone S/W application that serves as the Hemodynamic calculator. The S/W application performs POST-PROCESSING of the PhotoPlethismoGraphic (PPG) signal (Normally the PPG signal in Pulse Oximeters is used only to compute heart rate and SpO2). The raw data is transferred from the watch oximeter to the smartphone using a standard Bluetooth protocol. The Post-processing uses wavelet signal processing to estimate and display certain Hemodynamic parameters like (Blood Pressure) BP and CO in a continuous and graphical way on a standard Android Smartphone. In addition to the standard heart rate and SpO2, the application displays the measured PPG signal and estimated continues BP and CO. HeartBeat is the only device that can non-invasively estimate Continuous BP and its Cardiac Output component and the resistance component in a mobile wearable device. Differentiating between these 2 components can play a major role in helping the doctor to understand the effect of cardiovascular medications and Lifestyle interventions.

NCT ID: NCT01914861 Not yet recruiting - Clinical trials for Posttraumatic Stress Disorders

Cortisol Diurnal Variation and the Risk for Developing Post Traumatic Stress Disorder

Start date: July 2013
Phase: N/A
Study type: Observational

The purpose of this study is to examine a possible link between the time of day of exposure to a traumatic event and the risk of developing post-traumatic stress disorder. Clinical and biological correlates will also be examined from this perspective.

NCT ID: NCT01914445 Not yet recruiting - Clinical trials for Inflammatory Bowel Diseases

Chromoendoscopy of the Colon After Oral Administration of Indigo Carmine

Start date: August 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to examine whether oral administration of Indigo Carmine together with Polyethylene Glycol (PEG), the usual colon preparatory solution, can be used instead of staining during the examination itself.

NCT ID: NCT01912703 Not yet recruiting - Premature Infants Clinical Trials

The Long-term Neurodevelopmental Outcome After Intraventricular Hemorrhage (IVH)-Grades I-II in Preterm Infants at Ages 1-7 Years

Start date: December 2013
Phase: N/A
Study type: Observational

It is well-known that preterm delivery can be accompanied by complications. One of these complications is Intraventricular Hemorrhage (IVH). There are four degrees of IVH, according to severity. It is known that IVH Grades 3-4 can cause severe neurodevelopmental outcomes, including cerebral palsy (CP), hemiplegia, lower motor and cognitive skills and social difficulties. It is not known whether IVH Grades I-II have any of these effects and the aim of this study is to determine whether they do have any neurodevelopmental outcomes.

NCT ID: NCT01907438 Not yet recruiting - BRCA2 Gene Mutation Clinical Trials

Transformation Potential of E2 Exposed Breast Cancer Susceptibility Gene Mutation Heterozygous Epithelial Breast Cells

Start date: September 2013
Phase: N/A
Study type: Observational [Patient Registry]

Susceptibility to breast cancer is related to the combination of genetic, hormonal and multiple other environmental risk factors, such as mutations in the BRCA gene and excess exposure to exogenous estrogen, respectively. BRCA is a nuclear protein that maintains genome stability, by acting as a key player in the DNA repair complex. Recently, evidence has emerged that BRCA mutation heterozygosis itself enhances aborted DNA repair and can contribute to breast cancer initiation after exposure to irradiation. In our preliminary results on short-term lymphocyte cultures, we found additional evidence that healthy heterozygous BRCA1 and BRCA2 mutation carriers have a different response to DNA damage than do non-carriers. The main aim of our ongoing project is to identify the transcriptional modulation and transformation potential of normal BRCA1 and BRCA2 mutation heterozygous epithelial breast cells following irradiation and to examine how it is affected by exposure to estrogen. Our hypotheses will be investigated by RNA-seq and microRNA-seq in order to identify a unique molecular expression profile of the estrogen exposed cells following ionizing irradiation. Understanding the role of BRCA heterozygosity in cell response to exposure to estrogen and to irradiation may facilitate the development of more appropriate diagnostic and therapeutic strategies for these individuals.

NCT ID: NCT01899131 Not yet recruiting - Clinical trials for Preserve Crestal Bone Level and Gingival Margin Around Dental Implants

A Prospective Clinical and Radiographic Assessment on New Platform-switched Laser Lok Implants

Start date: October 2013
Phase: N/A
Study type: Interventional

1. To investigate the hard and soft tissue adaptation and maintenance to the Laser-Lok® microchannels permanent abutment/ new Laser-Lok® implant assembly by performing clinical and radiographic evaluations. 2. To investigate the effect of inter-implant spacing (minimum of 2 or 3 mm) on hard and soft tissues. 3. To perform clinical and radiographic evaluations on these abutment/implant assemblies up to 2 years.

NCT ID: NCT01895803 Not yet recruiting - Smoking Woman Clinical Trials

The Factors That Inhibit Women Who Smoke to do Pap Smear Test

Start date: July 2013
Phase: N/A
Study type: Observational

Discovery of factors affect the decision of the woman to perform or not to perform a Pap test.Participate in the study 100 women who smoke. Age range 18-60