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NCT ID: NCT02826486 Completed - Clinical trials for Metastatic Pancreatic Adenocarcinoma

Study Assessing Safety and Efficacy of Combination of BL-8040 and Pembrolizumab in Metastatic Pancreatic Cancer Patients (COMBAT/KEYNOTE-202)

COMBAT
Start date: September 2016
Phase: Phase 2
Study type: Interventional

This study will assess the efficacy and safety of BL-8040 in combination with pembrolizumab (Keytruda®) and BL8040/ Pembrolizumab in combination with liposomal irinotecan (Onivyde®)/5-fluorouracil/leucovorin (5-FU/LV) in subjects with metastatic pancreatic adenocarcinoma.

NCT ID: NCT02825641 Completed - Clinical trials for Medical Induction of Labor Affecting Newborn

Premature Rupture of Membranes With a Bishop Score<6: Comparison of Medical Induction/Expectant Management

Start date: August 1, 2016
Phase: N/A
Study type: Interventional

The study is intended to compare expectant management and on presentation labor induction in women with premature rupture of membranes. The means of labor induction and cervical ripening are either oxytocin or dinoprostone. Expectant management in this obstetrical state means waiting 24 hours from the onset of rupture of membranes and then commencing labor induction with either oxytocin or dinoprostone depending on the patient's obstetrical history and cervical condition. The investigators' hypothesis is that active management will lead to a higher rate of vaginal deliveries, a shorter interval between the time of rupture of membranes and the time of delivery, a lower rate of cesarean sections and a better obstetric result for the mother and the fetus/newborn.

NCT ID: NCT02825290 Recruiting - Embryo Transfer Clinical Trials

Modified Luteal Support for Frozen-Thawed Embryo Transfer - A Prospective Study

Start date: July 2016
Phase: Phase 4
Study type: Interventional

This study evaluates the outcomes of frozen-thawed embryo transfer (FET) success rate with modified luteal support - addition of a single injection of HCG and GnRH-agonist, on day of ET and 4 days later, respectively vs. traditional luteal support with vaginal progesterone only in ovulating women.

NCT ID: NCT02825186 Not yet recruiting - Ophthalmology Clinical Trials

Dexamethasone (Sterodex) Versus Loteprendol (Lotemax) Eye Drops Following Strabismus Surgery

Start date: July 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the efficacy and side effects of topical Loteprendol etabonate 0.5% (Lotemax) versus Dexamethasone 0.1% (Sterodex) following strabismus surgery.

NCT ID: NCT02825173 Completed - Clinical trials for Elective Surgical Procedures, Digestive System

Seal-G Safety Study

Start date: August 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to farther assess the safety of the Seal-G Surgical Sealant for the reinforcement and protection of gastrointestinal anastomosis.

NCT ID: NCT02824952 Recruiting - Clinical trials for Lung Cancer, Non-small Cell

Neo-adjuvant Trial With AZD9291 in EGFRm+ Stage IIIA/B NSCLC

Start date: November 1, 2018
Phase: Phase 2
Study type: Interventional

Patients will receive AZD9291 at a dose of 80 mg once daily. Systemic evaluation will be done by PET-CT scan after 6 weeks. In responding patients AZD9291 will be given orally 80 mg daily for 12 weeks. Non-responding patients will receive AZD9291 for the period of 6 or 12 weeks (according to the results of response assessment at each time-point).

NCT ID: NCT02824796 Completed - ADHD Clinical Trials

Group Training for Parents Whose Children Suffer From ADHD and Comorbidity Using a Behavioral-Dynamic Approach

SPBT
Start date: March 9, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a new parent training protocol for children with Attention Deficit Hyperactivity Disorder (ADHD) can over perform the state of the art Parent Training protocol (PBT) by increasing the long term effectiveness of the treatment, reducing the dropout rate and reducing the comorbidities.

NCT ID: NCT02823964 Completed - Cystic Fibrosis Clinical Trials

EASY: Extended Access to Sollpura Over Years

Start date: September 2016
Phase: Phase 4
Study type: Interventional

Liprotamase consists of 3 soluble, non-porcine digestive enzymes, lipase, protease, and amylase, combined in a fixed ratio. Liprotamase is stable in the stomach and can be formulated without enteric coating for administration either as a capsule or as a dosing solution dissolved in water or juice.

NCT ID: NCT02821702 Completed - Fertility Clinical Trials

Fertility Post Placenta Accrete

CSAC
Start date: July 2016
Phase: N/A
Study type: Interventional

This study is the first to investigate the fertility outcome and the influence on ovarian reserve after using uterine artery embolization during cesarean delivery.

NCT ID: NCT02819661 Recruiting - Clinical trials for Respiratory Depression

Respiratory Depression in Women With BMI≥30 Underwent Spinal Anesthesia With Intrathecal Morphine in Elective C-section

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

The study will examine whether there is a difference in the frequencies of respiratory depression among obese women receiving spinal anesthesia combined with opioids compared to women with normal BMI. If such a risk exists further investigation will be required to establish the proper criteria for the administration of morphine with spinal anesthesia to obese women.