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NCT ID: NCT00128167 Completed - Influenza Clinical Trials

Trivalent, Live, Cold Adapted Influenza Vaccine (CAIV-T) Against Inactivated Influenza Vaccine (TIV) in Children 6-59 Months of Age

Start date: October 2004
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to estimate the relative efficacy and assess the safety of CAIV-T compared to TIV.

NCT ID: NCT00125567 Completed - Clinical trials for Idiopathic Parkinson's Disease

Stalevo in Early Wearing-Off Patients

SEWOP
Start date: August 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to demonstrate in patients with Parkinson's disease that, when compared to levodopa/carbidopa, Stalevo will delay the time from initiation of study drug to the time an increase in antiparkinsonian medication is required due to inadequately controlled parkinsonian symptoms.

NCT ID: NCT00124982 Completed - Clinical trials for Rheumatoid Arthritis

Study of Abatacept (BMS-188667) in Subjects With Active Rheumatoid Arthritis on Background Non-biologic DMARDS (Disease Modifying Antirheumatic Drugs) Who Have an Inadequate Response to Anti-TNF Therapy

Start date: April 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to summarize the safety and tolerability of abatacept during 6 months of combined treatment with one or more of the background non-biologic disease modifying anti-rheumatic drugs (DMARDs) approved for rheumatoid arthritis (RA) in subjects with active RA. Secondary objectives assessed the clinical efficacy of combination treatment, including disease activity, physical function, and quality of life outcomes.

NCT ID: NCT00123487 Completed - Clinical trials for Leukemia, Lymphoblastic, Acute, Philadelphia-Positive

Advanced Chronic Myelogenous Leukemia (CML) - Follow On: Study of BMS-354825 in Subjects With CML

Start date: June 2005
Phase: Phase 3
Study type: Interventional

This is a phase III study of BMS-354825 in subjects with chronic myelogenous leukemia in accelerated phase, or in myeloid or lymphoid blast phase or with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia who are resistant or intolerant to imatinib mesylate (Gleevec).

NCT ID: NCT00123474 Completed - Clinical trials for Myeloid Leukemia, Chronic, Chronic-Phase

Chronic Myelogenous Leukemia (CML) - Follow on: Study of BMS-354825 in Subjects With CML

Start date: July 2005
Phase: Phase 3
Study type: Interventional

This is a phase III study of BMS-354825 in subjects with chronic phase Philadelphia chromosome or BCR-ABL positive chronic myelogenous leukemia, who are resistant or intolerant to imatinib mesylate (Gleevec).

NCT ID: NCT00122330 Completed - Clinical trials for Hemoglobinuria, Paroxysmal

Study Using Eculizumab in Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients

Start date: October 2004
Phase: Phase 3
Study type: Interventional

The primary objective is to evaluate the safety and efficacy of eculizumab in transfusion dependent patients with hemolytic PNH.

NCT ID: NCT00122317 Completed - Clinical trials for Paroxysmal Hemoglobinuria, Nocturnal

Extension Study of Eculizumab in Patients With Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH)

Start date: May 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the long-term safety of eculizumab in patients with transfusion dependent hemolytic PNH.

NCT ID: NCT00122304 Completed - Clinical trials for Hemoglobinuria, Paroxysmal

Study of Safety in Hemolytic Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Treated With Eculizumab

Start date: December 2004
Phase: Phase 3
Study type: Interventional

The primary objective is to evaluate the safety of eculizumab in patients with transfusion-dependent hemolytic PNH

NCT ID: NCT00113308 Completed - Clinical trials for Arthritis, Rheumatoid

COX-2 Inhibitor Study In Patients With Rheumatoid Arthritis

Start date: June 2005
Phase: Phase 3
Study type: Interventional

This study is being conducted to find out if an investigational drug called GW406381 can help people with rheumatoid arthritis.

NCT ID: NCT00104403 Completed - Clinical trials for Chemotherapy-Induced Nausea and Vomiting

Study Of Prevention of Chemo-Induced Nausea and Vomiting Caused By Moderately Emetogenic Chemotherapy

Start date: December 2004
Phase: Phase 2
Study type: Interventional

This study was designed to assess the safety and efficacy of different dosages and administration schedules of an investigational agent administered over 3 days when added to standard therapy used in the prevention of chemotherapy-induced nausea and vomiting in cancer patients. Subjects will be asked to complete daily diaries while on study medication. In addition subjects will be required to return to the investigational site several times during the course of the study for follow up safety assessments which may include blood samples for hematology and chemistry evaluations as well as physical exams. A final assessment will be preformed on study Day 20-30 at which time the subject will complete the study.