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NCT ID: NCT05378217 Completed - Clinical trials for Antimicrobial Drug Resistance

AMR-DetecTool for the Diagnostic of MDR Bacterial Infections

AMR DetecTool
Start date: July 18, 2022
Phase:
Study type: Observational

The fight against bacteria is one of the greatest challenges faced by societies, especially with the spread of multi drug resistant (MDR) bacteria. The failure to stop the spread of antimicrobial resistance (AMR) is due to a lack of fast detection methods and proper strategies. Novel, rapid and reliable detection and characterization tests are an urgent need for differentiating between bacterial and viral infections and identifying AMR, so that the most appropriate treatment can be given in a timely manner. AMR-DetecTool or NG Detectool is a detection system for the direct detection of AMR in clinical samples. The clinical sample is directly processed and a result indicating if the bacteria are resistant to the most relevant antibiotics is immediately shown. It allows for a dramatic reduction in the treatment decision time upon sample reception from 24 hours (current workflow) to 15-30 minutes.

NCT ID: NCT05358769 Completed - Clinical trials for Urinary Incontinence

A Study of Incoxil Food Supplement in Female Patients With Stress Dominant Urinary Incontinence.

Start date: April 27, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is compare the effectiveness of Incoxil food supplement and pelvic floor muscle training with pelvic floor muscle training alone in the treatment of women with stress dominant urinary incontinence.

NCT ID: NCT05357989 Completed - Clinical trials for Parkinson's Disease, Idiopathic

A Double-blind Study to Investigate Efficacy and Safety of Buntanetap Compared With Placebo in Participants With Early PD

Start date: August 3, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to measure safety and efficacy of buntanetap/posiphen capsules compared with placebo capsules in participants with early PD. Study details include: - The study duration will be up to 7-8 months. - The double-blind treatment duration will be up to 6 months. - There will be 5 in-clinic visits and 7 phone calls

NCT ID: NCT05355805 Completed - Clinical trials for Hidradenitis Suppurativa

Hidradenitis Suppurativa Phase 2b Pivotal Study of Izokibep

Start date: May 5, 2022
Phase: Phase 2
Study type: Interventional

Izokibep is a potent and selective inhibitor of interleukin 17A (IL-17A) that is being developed for treatment of hidradenitis suppurativa (HS). This study will evaluate the efficacy, safety, and immunogenicity of izokibep administered subcutaneously (SC) in adult subjects with moderate to severe HS.

NCT ID: NCT05349942 Completed - Palate; Deformity Clinical Trials

A Digital Method for Measurement of Palatal Asymmetry in Twins

Start date: January 10, 2019
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the digital palatal model as a possible tool of human identification.

NCT ID: NCT05342051 Completed - Clinical trials for Chronic Low-back Pain

The Effects of Immersion in 42℃ Thermal-mineral Water on Chronic Low-back Pain

Start date: August 15, 2021
Phase: N/A
Study type: Interventional

In this controlled, follow-up study the effects of immersion in 42℃ radon, natrium, calcium, bicarbonate content thermal-mineral water on clinical parameters and quality of life of patients with chronic low-back pain is evaluated. The participants in the intervention group are treated with balneotherapy plus usual care, while in the control group only with usual care. The planned participants number is 120. Follow up period is 3 months.

NCT ID: NCT05327920 Completed - Clinical trials for Rheumatoid Arthritis

An Observational Study to Assess the Impact of Upadacitinib in Adult Hungarian Participants With Moderate to Severe Rheumatoid Arthritis (RA) in Real-World Practice

UPDATE
Start date: April 20, 2022
Phase:
Study type: Observational

Rheumatoid Arthritis (RA) is a chronic inflammatory disease causing pain, stiffness, swelling and loss of joint function. Despite the range of treatment options for RA steadily increasing, many patients remain sub-optimally managed, with sustained clinical remission rarely achieved. This study will assess the impact of upadacitinib treatment on achievement of remission and low disease activity in moderate to severe RA Hungarian patients in the real-world setting. Upadacitinib is an approved drug for the treatment of adults with moderately to severely active RA. Adult participants with moderate-to-severe RA will be enrolled. Around 90 participants who are prescribed upadacitinib in routine clinical practice will be enrolled in the study in approximately 8 sites in Hungary. Participants will receive upadacitinib as prescribed by the physician and will be followed for approximately 12 months. There will be no additional burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the course of the study at a hospital or clinic and only data which are routinely collected during a regular visit will be utilized for this study.

NCT ID: NCT05313438 Completed - Clinical trials for Acute Decompensated Heart Failure

The STIM-ADHF Study

Start date: May 10, 2022
Phase: N/A
Study type: Interventional

The STIM-ADHF Study is a multi-center, observational study to assess the performance and safety of the CPNS System in patients with ADHF.

NCT ID: NCT05313360 Completed - Sarcopenia Clinical Trials

Association Between Sarcopenia and Urinary Incontinence And Effect Of Physical Activity Among Over 50 Years Old Adults

Start date: January 1, 2022
Phase:
Study type: Observational

As far as the investigators know, until this moment no research has investigated the prevalence of Sarcopenia in both sexes in Hungary. Additionally, no research discovered the association between sarcopenia and UI and the effect of physical activity level on these geriatric conditions in Hungary. Furthermore, it is known that Sarcopenia and UI are causing negative psychological, physical, and social effects on the geriatrics who are suffering from these conditions, not to mention the increase in health care costs. In an attempt to decrease these negative effects, there is a need for a deeper understanding of these conditions by identifying the relationship between them and understanding the risk factors that might cause them. The finding of this study would help with determining those risk factors that are causing these geriatric conditions (Sarcopenia and UI). Last, this study will provide accurate numbers and statistics to the Hungarian health organizations and educational institutions about the prevalence of sarcopenia and UI which will help shed the light on the importance of these problems among older adults in Hungary. This Cross-sectional study aim to: 1. Explore and study physical activity levels among aging adults of both sexes in Hungary. 2. To determine the prevalence of sarcopenia and UI among elderly individuals in Hungary. 3. Investigate the associations between sarcopenia and urinary incontinence among older adults (≥ 50 years). 4. Identify the effect of physical activity level on the occurrence of Sarcopenia and Urinary incontinence Hypothesis: 1. The investigators hypothesize that sarcopenia is a risk factor to have UI. 2. The investigators hypothesize that reduced physical activity level is also associated with sarcopenia and/or UI.

NCT ID: NCT05300867 Completed - Stroke, Acute Clinical Trials

Robotic Rehabilitation Treatment of Stroke Patients

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Storke results in severe deterioration in quality of life and exercise. Severe disorders need to be treated as soon as possible and they need to be rehabilitated quickly in order for motor functions to develop properly. In the acute / subacute phase, patients are given robotic treatment. In addition to the study of mtoros functions, the study of gait and codination is the primary result. Patients treated with soft exoskeleton receive 15 treatments and movement testing is performed continuously. Members of the control group receive standard rehabilitation therapy. After 3 weeks, both groups will participate in a control study and then in a repeat control study at week 6. Our main goal is to compare the results and determine the efficiency of the robotic device.