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NCT ID: NCT05109962 Completed - Clinical trials for Robertsonian Translocation

Management of Robertsonian Translocation PGT-SR Attempts

Start date: January 1, 2006
Phase:
Study type: Observational

to analyze if a probe strategy choice for PGT-SR studies of Robertsonian translocations (RT) influences the fate of embryos? Few studies discussed the importance of probe choices. However, those who did, demonstrated that analysis with locus specific probes improve a diagnosis of dubious results, and addition of a centromeric probe could affect the accuracy of diagnosis

NCT ID: NCT05109793 Active, not recruiting - Sandhoff Disease Clinical Trials

GM1 and GM2 Gangliosidosis PROspective Neurological Disease TrajectOry Study (PRONTO)

PRONTO
Start date: February 22, 2022
Phase:
Study type: Observational

The study aims to characterize prospectively longitudinal progression of neurological domains in GM1 and GM2 Gangliosidosis patients with high-quality standards (GCP compliant).

NCT ID: NCT05109728 Recruiting - Glioblastoma Clinical Trials

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

Start date: May 10, 2022
Phase: Phase 1
Study type: Interventional

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination with Standard of Care and in Recurrent Glioblastoma as a Single Agent

NCT ID: NCT05109676 Recruiting - IVF Clinical Trials

Monitoring of Progesterone Administered in Infertile Patients During a Cycle of Frozen Embryo Transfer.

PEKAPROGE
Start date: December 7, 2021
Phase: N/A
Study type: Interventional

During an In Vitro Fertilization (IVF) attempt, several embryos are obtained but not all of them can be transferred to the uterus in the same cycle due to the risk of multiple pregnancies. Thus, it is very common for these couples to benefit from cryopreservation. Patients scheduled for frozen embryo transfer (TEC) receive estrogen and progesterone replacement therapy to prepare the endometrium for implantation. Data from the literature recently showed that low progesterone on the day of embryo transfer was responsible for a significantly higher rate of implantation failure and miscarriage.

NCT ID: NCT05109546 Recruiting - COVID-19 Clinical Trials

Geriatric COVID-19 Serology

SeroGerCov
Start date: October 15, 2021
Phase:
Study type: Observational

Coronaviruses are important human and animal pathogens. At the end of 2019, a new coronavirus was identified as the cause of a cluster of pneumonia cases in Wuhan, a city in China's Hubei province. It quickly spread, leading to an epidemic across China, followed by an increasing number of cases in other countries around the world. In February 2020, the World Health Organization designated the disease COVID-19, which stands for coronavirus disease 2019. The virus that causes COVID-19 is SARS-CoV-2. The duration of protection during which a patient after infection and / or vaccination remains clinically protected and the evolution of their serology as well as their titre remains unknown

NCT ID: NCT05109468 Recruiting - Anxiety Clinical Trials

Assessment of Patients' Quality of Sexual Life After Anal Cancer Treatment

SEQUOIA
Start date: June 6, 2021
Phase:
Study type: Observational

The purpose of this this study, to evaluate the quality of sexual life of patients treated for anal cancer treated by radiotherapy, during their treatment, then 3 months after treatment and, finally, 2 years after treatment. cancer diagnosis.

NCT ID: NCT05109091 Active, not recruiting - Clinical trials for Multiple System Atrophy

Study of ATH434 in Participants With Multiple System Atrophy

Start date: July 1, 2022
Phase: Phase 2
Study type: Interventional

This study will assess the safety and efficacy of ATH434 in participants with Multiple System Atrophy

NCT ID: NCT05108961 Completed - Healthy Volunteers Clinical Trials

Evaluation of the Impact of an Acupuncture Session in Healthy Volunteers on the Kinetics of Cerebral Activity Using the Bispectral Index (BIS)

Bisprectral2
Start date: April 19, 2022
Phase: N/A
Study type: Interventional

To be able to have data on brain activity during an acupuncture session, this pilot study is necessary to evaluate the kinetics of the bispectral index. This research aims to evaluate the kinetics of the bispectral index in healthy volunteers during an acupuncture session, Sham acupuncture or resting in a lying position.

NCT ID: NCT05108948 Recruiting - Spinal Deformity Clinical Trials

Research of Factors Determining the Improvement of Quality of Life at One Year of Adult Patients Treated for Spinal Deformity (COFTASD)

COFTASD
Start date: October 23, 2021
Phase:
Study type: Observational

The objective of this study is to find the predictive factors of improvement of the quality of life of operated patients from spinal deformity.

NCT ID: NCT05108883 Recruiting - Clinical trials for Patients Presenting With Suspicion of Infection to the ED

Risk Stratification Using Midregional Proadrenomedullin in the ED

Start date: October 14, 2021
Phase: N/A
Study type: Interventional

Emergency departments (ED) are becoming increasingly over-crowded, with patients facing prolonged waiting times. Therefore, a safe and rapid assessment that identifies patients with low severity that could be treated as outpatients is essential for improving the workflow within the ED. The rationale of this IDEAL+ study is to safely decrease the number of hospital admissions through identification of low risk patients with the biomarker MR-proADM. This will has already been tested in the IDEAL - pilot study and results should be confirmed with this IDEAL+ study.