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NCT ID: NCT00689936 Completed - Multiple Myeloma Clinical Trials

Study to Determine Efficacy and Safety of Lenalidomide Plus Low-dose Dexamethasone Versus Melphalan, Prednisone, Thalidomide in Patients With Previously Untreated Multiple Myeloma

FIRST
Start date: August 21, 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the safety and efficacy of Lenalidomide plus low dose dexamethasone to that of the combination of melphalan, prednisone and thalidomide.

NCT ID: NCT00689520 Completed - Clinical trials for Venous Thromboembolism

Long-Term Low-Molecular-Weight Heparin Versus Oral Anticoagulants in Deep Venous Thrombosis

Start date: January 2002
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate whether low-molecular-weight heparin could be equally or more effective than oral anticoagulation in the long-term treatment of deep venous thrombosis.

NCT ID: NCT00689130 Completed - Pain Clinical Trials

ADVANCE: Assessment for Defining Variability in Anesthesia Through Novel Clinical EEG

CVI
Start date: May 2008
Phase: N/A
Study type: Observational

The present study is designed to compare prospectively whether sBIS, sEMG, or CVI variability (brain monitoring) can be used to predict unwanted intraoperative responses (high blood pressure, fast heart rate, tearing, etc.) to stimulation (pain) and to determine whether these intraoperative findings are related to patient-assessed postoperative pain scores. The hypothesis is that increases in these variability measures are associated with increased probability of unwanted responses. If confirmed, these variability measures may help anesthesia providers by highlighting periods of inadequate analgesia (pain relief).

NCT ID: NCT00689104 Completed - Clinical trials for Urinary Bladder, Overactive

Study to Assess the Efficacy and Safety of the Beta-3 Agonist Mirabegron (YM178) in Patients With Symptoms of Overactive Bladder

SCORPIO
Start date: April 28, 2008
Phase: Phase 3
Study type: Interventional

The study is intended to test efficacy, safety and tolerability of two doses of Mirabegron against placebo and compare the efficacy and safety with active comparator in patients with symptoms of overactive bladder.

NCT ID: NCT00688753 Completed - Carcinoma Clinical Trials

RAPTOR: RAD001 as Monotherapy in the Treatment of Advanced Papillary Renal Cell Tumors Program in Europe

MACS0460
Start date: July 2009
Phase: Phase 2
Study type: Interventional

To evaluate the preliminary efficacy and safety of RAD001 as monotherapy for first-line treatment of patients with metastatic papillary carcinoma of the kidney.

NCT ID: NCT00688740 Completed - Breast Cancer Clinical Trials

Docetaxel in Node Positive Adjuvant Breast Cancer

TAX316
Start date: June 1997
Phase: Phase 3
Study type: Interventional

The purpose of this study was to compare disease-free survival after treatment with docetaxel in combination with doxorubicin and cyclophosphamide to 5-fluorouracil in combination with doxorubicin and cyclophosphamide in operable breast cancer patients with positive axillary lymph nodes.

NCT ID: NCT00688688 Completed - Clinical trials for Urinary Bladder, Overactive

Study to Test the Long Term Safety and Efficacy of the Beta-3 Agonist Mirabegron (YM178) in Patients With Symptoms of Overactive Bladder

TAURUS
Start date: April 25, 2008
Phase: Phase 3
Study type: Interventional

The study is intended to test the safety, tolerability, efficacy of two doses of long term once daily (qd) treatment of Mirabegron in patients with symptoms of overactive bladder and secondly to compare these with active comparator.

NCT ID: NCT00688623 Completed - Carcinoma Clinical Trials

RAMSETE: RAD001 in Advanced and Metastatic Silent Neuro-endocrine Tumors in Europe

RAMSETE/CDE16
Start date: June 24, 2009
Phase: Phase 2
Study type: Interventional

To evaluate the preliminary efficacy and safety of RAD001 as monotherapy for first-line treatment of patients with metastatic papillary carcinoma of the kidney.

NCT ID: NCT00688571 Completed - Clinical trials for Heart Valve Diseases

Melody Transcatheter Pulmonary Valve (TPV) Post-Market Surveillance Study

Start date: October 2007
Phase: N/A
Study type: Interventional

This non-randomized, prospective, interventional observational multi-center study is designed to assess the long-term clinical performance of the Medtronic Melody™ Transcatheter Pulmonary Valve (TPV) in the post market environment over a period of five years after transcatheter implantation in patients with dysfunctional RVOT conduits. In addition, the quality of life of implanted subjects will be assessed over five years.

NCT ID: NCT00688376 Completed - Clinical trials for Attention Impairment

Efficacy and Safety of Donepezil Hydrochloride in Preadolescent and Adolescent Children With Attention Impairment Following Cancer Treatment

Start date: July 2, 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety and tolerability of donepezil in children with persistent attention impairment that is present at least 12 months after the completion of cancer treatment.