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NCT ID: NCT01214720 Completed - Pancreatic Cancer Clinical Trials

A Study of Avastin (Bevacizumab) Added to a Chemotherapeutic Regimen in Patients With Metastatic Pancreatic Cancer

Start date: July 2005
Phase: Phase 3
Study type: Interventional

This study will evaluate efficacy, safety and tolerability of Avastin versus placebo added to a chemotherapeutic regimen in patients with metastatic pancreatic cancer. The anticipated time of study treatment is until confirmed evidence of disease progression, and the target sample size is 500+ individuals.

NCT ID: NCT01213836 Completed - Schizophrenia Clinical Trials

Compare the Effect on Cognitive Functioning of Two Formulations of Seroquel, Seroquel XR and IR in Patients With Stable Schizophrenia

eXtRa
Start date: November 2010
Phase: Phase 4
Study type: Interventional

This will be a phase IV 20 -32 day prospective, double blind, double-dummy, randomised crossover study that will evaluate the effect of quetiapine XR and quetiapine IR on cognitive performance in patients with schizophrenia stabilized on a single antipsychotic medication.

NCT ID: NCT01213602 Completed - Clinical trials for Knee Replacement Surgery

Bilateral Bispectral Index (BIS)-Monitoring in Trauma Surgery

Start date: February 2010
Phase: N/A
Study type: Observational

The principal objective is to notice the relevance of timing performance of femoral block for knee replacement surgery during general anesthesia and analyze the relationship with bilateral bispectral index (BIS) monitoring during induction and maintenance of anesthesia. Otherwise the investigators try to investigate if the timing of performance of this block influence in postoperative variables as pain or blood loss.

NCT ID: NCT01212991 Completed - Prostate Cancer Clinical Trials

A Safety and Efficacy Study of Oral MDV3100 in Chemotherapy-Naive Patients With Progressive Metastatic Prostate Cancer

PREVAIL
Start date: September 16, 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the benefit of enzalutamide versus placebo as assessed by overall survival and progression-free survival in patients with progressive metastatic prostate cancer who have failed androgen deprivation therapy but not yet received chemotherapy.

NCT ID: NCT01212770 Completed - Psoriatic Arthritis Clinical Trials

PALACE 3: Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis

PALACE 3
Start date: September 30, 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether apremilast is safe and effective in the treatment of patients with psoriatic arthritis and a qualifying psoriasis lesion. Apremilast is proposed to improve signs and symptoms of psoriatic arthritis (tender and swollen joints, pain, physical function) in treated patients.

NCT ID: NCT01212757 Completed - Psoriatic Arthritis Clinical Trials

PALACE 2: Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis

PALACE2
Start date: September 27, 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether apremilast is safe and effective in the treatment of patients with psoriatic arthritis. Apremilast is proposed to improve signs and symptoms of psoriatic arthritis (tender and swollen joints, pain, physical function) in treated patients.

NCT ID: NCT01211873 Completed - Clinical trials for Central Nervous System Diseases

Safety and Efficacy Evaluation of DOTAREM® in MRI of Central Nervous System (CNS) Lesions

SENTIO
Start date: September 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to look at the safety (what are the side effects)and efficacy (how well does it work) of Dotarem® when used in taking images of the brain / spine. The results will be compared to the results of MRI taken without Dotarem.

NCT ID: NCT01211587 Completed - Clinical trials for Parkinson's Disease With Cognitive Impairments

A Trial to Explore the Potential Benefit of Safinamide on Cognitive Impairment Associated With Parkinson's Disease

Start date: September 2010
Phase: Phase 2
Study type: Interventional

The purpose of this research trial is to determine if safinamide (experimental drug) can improve cognition in cognitively impaired but non-demented Parkinson's disease patients. The word "experimental" means the trial drug is not approved by Health Authorities (government authorities) and is still being tested for safety and effectiveness. Approximately one hundred (100) patients will participate in this research trial. The research trial will be conducted in approximately thirty (30) medical centers in the following countries: Argentina, Canada, Italy, Peru, South Africa, Spain and USA. The research trial will last until June 2012.

NCT ID: NCT01210690 Completed - Epilepsy Clinical Trials

Observational Study in Infants Who Are Prescribed Treatment With Keppra® (Levetiracetam) Oral Solution

Start date: January 2011
Phase: N/A
Study type: Observational

The purpose of this observational study is to broaden the knowledge of the known safety and efficacy profile of Keppra® (Levetiracetam) oral solution in epileptic infants younger than 12 months when treated according to routine clinical practice. Their data will be collected until they reach the age of 13 months.

NCT ID: NCT01209169 Completed - Acute Kidney Injury Clinical Trials

Evaluation of Novel Biomarkers From Acutely Ill Patients at Risk for Acute Kidney Injury

Start date: September 2010
Phase: N/A
Study type: Observational

The purpose of this study is to collect blood and urine samples that may help identify and validate biomarkers for the early detection and risk assessment of acute kidney injury (AKI).