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NCT ID: NCT01358721 Completed - Clinical trials for Renal Cell Carcinoma

Phase I Biomarker Study (BMS-936558)

Start date: September 23, 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacodynamic and biologic properties of BMS-936558 in subjects with metastatic renal cell carcinoma.

NCT ID: NCT01358578 Completed - Clinical trials for Chronic Plaque Psoriasis

Safety and Efficacy of Secukinumab Compared to Etanercept in Subjects With Moderate to Severe, Chronic Plaque-Type Psoriasis

FIXTURE
Start date: June 2011
Phase: Phase 3
Study type: Interventional

This study will assess the safety and efficacy of secukinumab compared to placebo and etanercept in patients that have moderate to severe, chronic, plaque-type psoriasis.

NCT ID: NCT01358292 Completed - Tibial Fractures Clinical Trials

Efficacy Study of Surgical Technique in Intramedullary Tibia Nailing, Using Trigen META Tibia Nails

TrigenMETA
Start date: February 2011
Phase: Phase 4
Study type: Interventional

Multicentre Prospective Randomized Clinical Trial, to evaluate patients after surgery for extra-articular tibial fractures treated with Smith& Nephew's Trigen META intramedullary nailing system; comparing two surgical techniques: Group A=standard technique(90º of knee flexion) and Group B=with the semi-extended surgical technique. (2*100 patients) Research Objectives: The primary research objectives are to evaluate: i) anterior knee pain and ii) the nail position and overall fracture alignment Outcome Measures: 1. Nail positioning by means of intra-operative fluoroscopy and post operative x-rays. 2. Anterior Knee pain by means of VAS-scores, a Kneeling test and Subjective outcomes by means of Patient questionnaires 3. Knee-related adverse events 4. Overall fracture alignment

NCT ID: NCT01358266 Completed - Clinical trials for Uveitis; Posterior, Disorder

Study Assessing Double-masked Uveitis Treatment

SAKURA
Start date: May 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of intravitreal injections of DE-109 ophthalmic solution.

NCT ID: NCT01357837 Completed - Clinical trials for Osteoarthritis of the Knee

Assessment of GRT6005 in Painful Osteoarthritis of the Knee

Start date: May 2011
Phase: Phase 2
Study type: Interventional

The purpose of the trial is to determine whether GRT6005 is effective in patients with pain due to osteoarthritis of the knee.

NCT ID: NCT01357655 Completed - Leukemia Clinical Trials

Phase 2 Dasatinib Combo With Smoothened (SMO) Antagonist (BMS-833923)

Start date: September 2011
Phase: Phase 2
Study type: Interventional

The purpose of the study is to compare response rates in newly diagnosed Chronic Phase (CP) CML subjects treated with dasatinib plus BMS-833923 versus dasatinib alone.

NCT ID: NCT01357239 Completed - Fragile X Syndrome Clinical Trials

Safety and Efficacy of AFQ056 in Adolescent Patients With Fragile X Syndrome

Start date: May 2011
Phase: Phase 2
Study type: Interventional

This Phase IIb study is designed to assess whether 3 doses of AFQ056 are safe and effective in treating the behavioral symptoms of Fragile X Syndrome.

NCT ID: NCT01356797 Completed - Pain Clinical Trials

Selective Unilateral Spinal Anesthesia Versus Selective Sensory Spinal Anesthesia for Knee Arthroscopy Surgery

Start date: May 2011
Phase: Phase 4
Study type: Interventional

Background: Selective unilateral spinal anesthesia is the gold standard spinal anesthesia technique for knee arthroscopy. Selective sensory spinal anesthesia has recently been validated for this surgery. Both selective techniques are specially indicated for ambulatory surgery because of PACU fast track, low discharge home time and high patient satisfaction. This study compares both spinal techniques for knee arthroscopy surgery.

NCT ID: NCT01355627 Completed - Clinical trials for Cerebrospinal Fluid Leaks

TASALL - TachoSil® Against Liquor Leak

Start date: April 2011
Phase: Phase 3
Study type: Interventional

The primary objective is to demonstrate superiority of TachoSil® compared to current practice as an adjunct in sealing the dura mater. The efficacy of the dura mater sealing must be evaluated post-operatively. The secondary objective is to evaluate the safety of TachoSil® as an adjunct in sealing the dura mater. The trial population will consist of 726 randomised (1:1) patients elected for skull base surgery. The trial duration consists of screening, surgery, efficacy follow-up after 7±1 weeks and safety follow-up 28±2 weeks after surgery.

NCT ID: NCT01354834 Completed - Infertility Clinical Trials

Assessment of the Effectiveness of Menopur in Intrauterine Insemination

Start date: March 2004
Phase: N/A
Study type: Observational

The purpose of this study is to assess the effectiveness of Menopur to achieve clinical pregnancy in females undergoing intrauterine insemination in clinical practice.