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NCT ID: NCT02264418 Completed - Solid Tumours Clinical Trials

Safety and Tolerability of ODM-203 in Subjects With Advanced Solid Tumours

KIDES-203
Start date: September 18, 2014
Phase: Phase 1
Study type: Interventional

The purpose of this first-in-human study is to evaluate the safety and tolerability of escalating doses of ODM-203 in subjects with advanced solid tumours and to determine the maximum tolerated dose and dose limiting toxicities.

NCT ID: NCT02262676 Completed - Atrial Fibrillation Clinical Trials

Observational Study to Assess Sociodemographic and Clinical Features of Patients Treated With Rivaroxaban in Routine Clinical Practice of Hematologists, Cardiologists and Internists of Spain

HEROIC
Start date: October 2014
Phase: N/A
Study type: Observational

Depict demographic and clinical features of patients with atrial fibrillation treated with rivaroxaban to prevent stroke and pulmonary embolism in routine clinical practice

NCT ID: NCT02262273 Completed - Clinical trials for Platinum-sensitive Recurrent Serous Ovarian Cancer

OSCA - Olaparib Standard of CAre Study

OSCA
Start date: October 2014
Phase: N/A
Study type: Observational

This study will be carried out as a retrospective, non-interventional observational review of medical records for patients in multiple countries with platinum-sensitive recurrent serous ovarian cancer. The objectives are to describe in a real-world population, treatment patterns, BRCA mutation testing and results, overall survival, health care utilization and also to estimate rates of selected treatment- and/or disease-related side effects

NCT ID: NCT02261987 Completed - Cystic Fibrosis Clinical Trials

Resistive Inspiratory Manoeuvre as Airway Clearance Technique in Cystic Fibrosis

Start date: November 2014
Phase: N/A
Study type: Interventional

This trial aims to analyze whether the resistive inspiratory manoeuvre (RIM) performed previously to autogenic drainage (AD) technique improves the effectiveness in terms of mucus clearance during a typical bronchial drainage session in adults, stable CF patients.

NCT ID: NCT02261974 Completed - Clinical trials for Vaginal Laxity Following Childbirth

VIveve Treatment of the Vaginal Introitus to EValuate Effectiveness

VIVEVE I
Start date: January 2015
Phase: N/A
Study type: Interventional

Outside United States (OUS) Post-Market Parallel Group Exploratory Study Design The objective of this study is to determine the safety and effectiveness of the Viveve System to treat the vaginal introitus in women following vaginal birth(s) and in so doing improving vaginal laxity.

NCT ID: NCT02261896 Completed - Clinical trials for Pancreatic Cystic Lesion

Antibiotic Prophylaxis for Endoscopic Ultrasound Guided Fine Needle Aspiration of Pancreatic Cystic Lesions

Start date: October 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether the use of antibiotic prophylaxis is appropriate when performing a pancreatic cyst fine needle aspiration guided by endoscopic ultrasonography.

NCT ID: NCT02261714 Completed - Clinical trials for Pancreatic Cancer, Resected

Antigen-specific Cancer Immunotherapy (TG01) and Gemcitabine as Adjuvant Therapy in Resected Pancreatic Cancer

Start date: December 2012
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigate the effect of TG01 and Granulocyte macrophage colony stimulating factor (GM-CSF) when given in addition to gemcitabine (chemotherapy) and - Understand any possible side effects of the additional use of TG01/GM-CSF with gemcitabine - Investigate whether TG01/GM-CSF when given with gemcitabine can produce an immune response - Investigate if the treatment can delay or reduce recurrence of the disease

NCT ID: NCT02261220 Completed - Clinical trials for Advanced Solid Tumors

A Phase 1 Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Solid Tumors

Start date: October 13, 2014
Phase: Phase 1
Study type: Interventional

This is a multicenter, open-label, dose-exploration and dose-expansion study to evaluate the safety, tolerability, antitumor activity, PK and immunogenicity of MEDI4736 in combination with tremelimumab in subjects with select advanced solid tumors.

NCT ID: NCT02260986 Completed - Atopic Dermatitis Clinical Trials

Study to Assess the Efficacy and Long-term Safety of Dupilumab (REGN668/SAR231893) in Adult Participants With Moderate-to-Severe Atopic Dermatitis

CHRONOS
Start date: September 2014
Phase: Phase 3
Study type: Interventional

The primary objective of the study was to demonstrate the efficacy of Dupilumab administered concomitantly with topical corticosteroid (TCS) through Week 16 in adult participants with moderate-to-severe atopic dermatitis (AD) compared to placebo administered concomitantly with TCS.

NCT ID: NCT02260791 Completed - Clinical trials for Arthritis, Rheumatoid

A Study to Compare FKB327 Efficacy and Safety With Humira® in Rheumatoid Arthritis Patients

ARABESC
Start date: December 2014
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare the effectiveness and safety of FKB327 in comparison to Humira® in rheumatoid arthritis patients who have inadequate disease control on methotrexate.