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NCT ID: NCT02549092 Completed - Clinical trials for Advanced Parkinson's Disease

A Study to Examine the Effect of Levodopa-Carbidopa Intestinal Gel (LCIG) Therapy Relative to That of Optimized Medical Treatment (OMT) on Non-motor Symptoms (NMS) Associated With Advanced Parkinson's Disease (PD)

Start date: October 26, 2015
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to examine the effect of LCIG relative to that of OMT on NMS associated with PD.

NCT ID: NCT02548845 Completed - Hyponatremia Clinical Trials

An Observational Study to Describe the Adherence to the SEOM Algorithm for the Treatment of Hyponatraemia in Spain

ALGA
Start date: December 2015
Phase:
Study type: Observational

In 2014, the Spanish Sociedad Española de Oncología Médica (SEOM) algorithm for the treatment of hyponatraemia secondary to to syndrome of inappropriate antidiuretic hormone (SIADH) in oncology patients was developed. Since it is hypothesised that the adherence to the SEOM algorithm is not 100%, the current retrospective non-interventional study will investigate the perceived and actual adherence of participating centres to the SEOM algorithm and its impact on patient outcomes

NCT ID: NCT02548780 Completed - Clinical trials for Hepatocellular Carcinoma

LifePearl-Doxo Pharmacokinetic (PK) Study

Start date: April 2016
Phase: N/A
Study type: Interventional

The primary purpose of the study is to evaluate the pharmacokinetic profile, safety, and efficacy of LifePearlâ„¢ microspheres loaded with Doxorubicin in the treatment of unresectable HCC.

NCT ID: NCT02548364 Completed - Clinical trials for Myocardial Infarction

Effect of Vitamin D on Ventricular Remodeling in Patients With Acute Myocardial Infarction (VITDAMI)

VITDAMI
Start date: October 2015
Phase: Phase 3
Study type: Interventional

To study the effect of calcifediol on left ventricular remodeling, mineral metabolism, plasma levels of several prognostic biomarkers and on endothelial function after an anterior myocardial infarction.

NCT ID: NCT02548325 Completed - Hepatitis B Clinical Trials

Prevalence of Hepatitis B in Vallés Occidental. Observational Multicentric Study

Start date: June 1, 2014
Phase:
Study type: Observational

The aim of this study is to evaluate the prevalence of hepatitis B in Vallés Occidental. Also, describe the stage of the disease, and whether if they are under medical treatment or not.

NCT ID: NCT02548143 Completed - Hemophilia Clinical Trials

LR769 in Congenital Hemophilia Patients With Inhibitors Undergoing Elective Surgery or Invasive Procedures

PerSept3
Start date: August 25, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study, PerSept 3, is to evaluate LR769 for the prevention of excessive bleeding and achievement of hemostasis in congenital hemophilia A or B patients who have inhibitors to Factor VIII or Factor IX , are aged 6 months to 75 years, inclusive; and who are undergoing elective surgical or other invasive procedures. Administration of LR769 will be performed just prior to surgery/procedure and will be repeated during and after the surgery/procedure to achieve and maintain adequate hemostasis as determined by the investigator's judgment.

NCT ID: NCT02547935 Completed - Clinical trials for Type 2 Diabetes Mellitus, CKD and Albuminuria

A Study to Evaluate the Effect of Dapagliflozin With and Without Saxagliptin on Albuminuria, and to Investigate the Effect of Dapagliflozin and Saxagliptin on HbA1c in Patients With Type 2 Diabetes and CKD

Start date: September 21, 2015
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this clinical research study is to determine whether dapagliflozin alone or in combination with saxagliptin can decrease albuminuria and improve glycemic control in patients with Type 2 diabetes, albuminuria and renal impairment (CKD). The study is planned to randomize a total of 450 patients (150 patients per treatment arm)

NCT ID: NCT02547922 Completed - Lupus Nephritis Clinical Trials

Safety and Efficacy of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Proliferative Lupus Nephritis

TULIP-LN1
Start date: November 4, 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of an intravenous treatment regimen of two doses of anifrolumab versus placebo in adult subjects with active proliferative lupus nephritis (LN).

NCT ID: NCT02547844 Completed - HIV-1 Clinical Trials

Evolution of Plasma Lipid Profile in Patients With HIV1 Who Change Atripla to Eviplera Compared to Continue With Atripla

Start date: September 2015
Phase: Phase 4
Study type: Interventional

To compare the lipidomic profile in patients with HIV-1 with viral suppression changing efavirenz + emtricitabine + tenofovir (Atripla) to rilpivirine + emtricitabine + tenofovir (Eviplera®) versus a group of patients that continue with Atripla®.

NCT ID: NCT02547701 Completed - Onychomycosis Clinical Trials

Clinical Trial on Onychomycosis With P-3058 Nail Solution in Pediatric Population

Start date: August 2014
Phase: Phase 3
Study type: Interventional

Pediatric patients affected by mild-to-moderate distal subungual onychomycosis (DSO) or affected by white superficial onychomycosis (WSO), due to dermatophytes, will be treated topically with P-3058 nail solution according to the appropriate treatment schedule.