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NCT ID: NCT02658955 Completed - Clinical trials for Closure of Abdominal Wall

Changing Technique of Abdominal Wall Closure (PHACPA)

PHACPA
Start date: June 2016
Phase: N/A
Study type: Interventional

Implementing guidelines of EHS for abdominal wall closure in all specialities of a General Hospital. Migrating from large stitch technique to short stitch technique.

NCT ID: NCT02658890 Completed - Clinical trials for Non-Small Cell Lung Cancer

An Investigational Immuno-therapy Study of BMS-986205 Given in Combination With Nivolumab and in Combination With Both Nivolumab and Ipilimumab in Cancers That Are Advanced or Have Spread

Start date: April 14, 2016
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of the study is to determine safety and effectiveness of experimental medication BMS-986205 when combined with Nivolumab and in combination with both Nivolumab and Ipilimumab in patients with cancers that are advanced or have spread. Pharmacokinetics and pharmacodynamics of BMS-986205 when combined with Nivolumab and in combination with Nivolumab and Ipilimumab in this patient population will also be assessed.

NCT ID: NCT02658175 Completed - Clinical trials for Familial Chylomicronemia Syndrome

The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Chylomicronemia Syndrome

Start date: December 23, 2015
Phase: Phase 3
Study type: Interventional

An open-label study of volanesorsen (ISIS 304801) administered subcutaneously to participants with FCS.

NCT ID: NCT02657915 Completed - Clinical trials for Acute Optic Neuritis

Long-Term Assessment of Remyelinating Therapy

RENEWED
Start date: March 10, 2016
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to assess full-field visual evoked potential (FF-VEP) latency in subjects who were enrolled in Study NCT01721161 2 years (+ up to 12 months) after the last study visit. The secondary objective is to assess clinical progression and severity of central nervous system (CNS) demyelinating disease in subjects who were enrolled in Study NCT01721161 2 years (+ up to 12 months) after the last study visit. Intervention was administered in the previous study. The participants, investigator and outcome assessors remain blinded in this follow-up study.

NCT ID: NCT02657681 Completed - Parkinson's Disease Clinical Trials

Prevention of Levodopa-induced Dyskinesias by Transcranial Static Magnetic Field Stimulation (tSMS)

Start date: October 2015
Phase: Phase 2
Study type: Interventional

This is a randomized sham-controlled double-blind study to test the hypothesis that transcranial static magnetic field stimulation (tSMS) of the motor cortex improves levodopa-induced dyskinesias in patients with Parkinson's disease. Half of the patients will receive real tSMS treatment, the other half will receive sham treatment (placebo).

NCT ID: NCT02657434 Completed - Clinical trials for Non-Small Cell Lung Cancer

A Study of Atezolizumab in Combination With Carboplatin or Cisplatin + Pemetrexed Compared With Carboplatin or Cisplatin + Pemetrexed in Participants Who Are Chemotherapy-Naive and Have Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (IMpower 132)

Start date: April 30, 2016
Phase: Phase 3
Study type: Interventional

This is a randomized, Phase III, multicenter, open-label study designed to evaluate the safety and efficacy of atezolizumab in combination with cisplatin or carboplatin + pemetrexed compared with treatment with cisplatin or carboplatin + pemetrexed in participants who are chemotherapy-naive and have Stage IV non-squamous NSCLC. Eligible participants will be randomized by a 1:1 ratio into 2 groups: Arm A (Atezolizumab + Carboplatin or Cisplatin + Pemetrexed) and Arm B (Carboplatin or Cisplatin + Pemetrexed). The study will be conducted in two phases: Induction Phase and Maintenance Phase.

NCT ID: NCT02657057 Completed - Overactive Bladder Clinical Trials

Effects of Transcutaneous and Percutaneous PTNS on Idiopathic OAB

Start date: November 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if Transcutaneous Tibial Nerve Stimulation (TENS) is as effective as Percutaneous Tibial Nerve Stimulation (PTNS) as therapeutic option for subjects with Idiopathic Overactive Bladder (OAB) who have failed conventional therapy.

NCT ID: NCT02656238 Completed - Clinical trials for Chronic Thromboembolic Pulmonary Hypertension

New International CTEPH Database

Start date: February 2015
Phase:
Study type: Observational [Patient Registry]

The New International CTEPH Database is a prospective, observational multi-center disease registry run by the International CTEPH Association (ICA), which will collect data in chronic thromboembolic pulmonary hypertension (CTEPH) patients worldwide. The registry will run for approximately 5 years. Its objective is to provide an overview on epidemiology of CTEPH, mode of diagnosis and treatment approaches worldwide as well as determinants of long-term outcomes as measured by New York Heart Association (NYHA) functional class and survival. The data collected will improve the knowledge and understanding of this condition, support the further development of diagnosis and treatment guidelines for patients with CTEPH, and contribute to improving patient care in the long-term.

NCT ID: NCT02655887 Completed - Clinical trials for Peripheral Vascular Disease

BARD® The VENOVO™ Venous Stent Study for Treatment of Iliofemoral Occlusive Disease

VERNACULAR
Start date: June 15, 2016
Phase: N/A
Study type: Interventional

The BARD® Venovo™ Venous Stent Study is a non-randomized clinical study intended to collect confirmatory evidence of the safety and effectiveness of the Venous Stent for the treatment of iliofemoral occlusive disease.

NCT ID: NCT02655419 Completed - Clinical trials for Complicated Intra-Abdominal Infections, cIAIs

Determine the PK and Safety and Tolerability of ATM-AVI for the Treatment of cIAIs in Hospitalized Adults (REJUVENATE)

Start date: May 19, 2016
Phase: Phase 2
Study type: Interventional

Determine the PK and safety and tolerability of aztreonam-avibactam (ATM-AVI) in the treatment of hospitalized adults with cIAI