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NCT ID: NCT01769196 Terminated - Clinical trials for Idiopathic Pulmonary Fibrosis

A Phase 2 Study to See if Simtuzumab (GS-6624) is Safe and Works in Idiopathic Pulmonary Fibrosis (IPF)

RAINIER
Start date: January 2013
Phase: Phase 2
Study type: Interventional

This study is to evaluate the efficacy and safety of simtuzumab (GS-6624) in adults with idiopathic pulmonary fibrosis.

NCT ID: NCT01768988 Terminated - Pancreatic Cancer Clinical Trials

Efficacy Of Pregabalin In The Treatment Of Pancreatic Cancer Pain. A Randomized Controlled Double-Blind, Parallel Group Study

PANPAIN/1
Start date: August 2012
Phase: Phase 4
Study type: Interventional

This is a randomized, double blind controlled, parallel arms trial, aimed to assess the efficacy of pregabalin on pancreatic cancer induced abdominal pain. The goals of this study include (1) assessing the analgesic effect of pregabalin in comparison to placebo; assessing the presence of central sensitization and its potential reversion by Pregabalin; (3) assessing quality of life of patients treated with pregabalin in comparison to placebo; (4) to compare adverse effects in patients treated with Pregabalin in comparison to placebo; (5) to compare anxiety and depression in patients treated with pregabalin in comparison to placebo.

NCT ID: NCT01767857 Terminated - Clinical trials for Metastatic Colorectal Cancer

A Phase III Study of Xilonix in Patients With Advanced Colorectal Cancer

XCITE
Start date: March 31, 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if the True Human Monoclonal antibody Xilonix (MABp1) can prolong the life of colorectal carcinoma patients that are refractory to standard therapy.

NCT ID: NCT01766336 Terminated - Alzheimer's Disease Clinical Trials

A 36-Week Safety Extension Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease

Start date: January 2013
Phase: Phase 2
Study type: Interventional

To evaluate the safety and tolerability of ELND005 treatment with up to 36 weeks exposure, in Moderate to Severe AD patients with agitation and aggression.

NCT ID: NCT01765842 Terminated - Lupus Nephritis Clinical Trials

Comparison of the Efficacy of Two Rituximab Treatment Regimens in Patients With Lupus Nephropathy

RITULUP
Start date: November 2012
Phase: Phase 3
Study type: Interventional

Comparison of the Efficacy of Two Rituximab Treatment Regimens in Patients With Lupus Nephropathy Resistant to Conventional Treatments

NCT ID: NCT01764997 Terminated - Clinical trials for Rheumatoid Arthritis

An Evaluation of Sarilumab Plus Methotrexate Compared to Etanercept Plus Methotrexate in RA Patients Not Responding to Adalimumab Plus Methotrexate

RA-COMPARE
Start date: April 2013
Phase: Phase 3
Study type: Interventional

Primary Objective: To demonstrate the treatment effect of sarilumab and methotrexate (MTX) compared to etanercept and methotrexate (MTX) in patients with rheumatoid arthritis (RA) and an inadequate response to adalimumab and methotrexate by evaluation of the Disease Activity Score for 28 joints (DAS28). Secondary Objectives: To assess the signs and symptoms of rheumatoid arthritis (RA) in patients taking sarilumab in combination with methotrexate (MTX). To assess the quality of life of patients with rheumatoid arthritis (RA) taking sarilumab in combination with methotrexate (MTX). To assess the safety and tolerability of sarilumab in combination with methotrexate (MTX) in patients with rheumatoid arthritis (RA).

NCT ID: NCT01761591 Terminated - Clinical trials for Coronary Artery Disease

Acrobat Coronary Stent System Effectiveness European Study

ACES
Start date: December 2012
Phase: N/A
Study type: Interventional

The purpose of this randomized controlled trial (RCT) is to demonstrate the clinical benefit and impact on resource utilization of percutaneous coronary interventions (PCI) with the Svelte Acrobat Stent System compared to any other CE marked bare metal stent (BMS) implantable via direct stenting or after lesion pre-dilation, in patients with coronary lesions that are eligible for direct stenting and who are recruited and treated so as to reflect real-life routine practice.

NCT ID: NCT01761201 Terminated - Clinical trials for Latent Tuberculosis Infection

"Efficacy and Safety of Levofloxacin vs Isoniazid in Latent Tuberculosis Infection in Liver Transplant Patients".

FLISH-ILT
Start date: January 2012
Phase: Phase 3
Study type: Interventional

A multicenter, prospective, non-inferiority, randomized and open clinical trial comparing levofloxacin with isoniazid in the treatment of latent tuberculosis infection in patients eligible for liver transplantation. Patients over 18 years of age on the waiting list for liver transplantation. Sample size: n=870 patients. HYPOTHESIS Levofloxacin treatment of latent tuberculosis infection, begun while on the waiting list for liver transplantation, is safer and not less effective than isoniazid treatment begun after transplantation when liver function is stable.

NCT ID: NCT01757691 Terminated - Clinical trials for Acute Demylelinating Optic Neuritis

Fingolimod (FTY720) in Acute Demyelinating Optic Neuritis (ADON)

Start date: August 2013
Phase: Phase 2
Study type: Interventional

To evaluate the efficacy and safety of fingolimod 0.5mg versus placebo in patients with suspected acute demyelinating optic neuritis (ADON) receiving standard steroid treatment

NCT ID: NCT01751802 Terminated - Clinical trials for Self-injurious Behavior

Ecopipam Treatment of Self-Injurious Behavior in Subjects With Lesch-Nyhan Disease

Start date: December 2012
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to gather scientific information about the effectiveness and safety of the study drug, Ecopipam (PSYRX 101), for the treatment of self-injurious behaviors when compared with the effectiveness and safety of placebo (inactive substance) in subjects with Lesch-Nyhan Disease.