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NCT ID: NCT04691609 Recruiting - ACS-COVID-19-Assiut Clinical Trials

Assiut University Registry for ACS Patients During COVID-19 Pandemic

Start date: March 1, 2020
Phase:
Study type: Observational

To register pathological events occurring to all acute coronary syndrome patients coming to Assiut university heart hospital through one year during COVID- 19 pandemic

NCT ID: NCT04688957 Recruiting - Clinical trials for Maxillary Sinus Lift

Osseodensification by Densah Burs Versus Osteotome

Start date: December 12, 2020
Phase: N/A
Study type: Interventional

implant placement in the posterior maxilla is problematic, not only due to inferior properties of bone but also due to loss of vertical bone height which happens after extraction of posterior teeth. when the required additional height is few millimeters, indirect transcresta sinus lifting procedures are recommended. This study compares sinus lifting using the conventional osteotome versus the osseodensification with densah burs.

NCT ID: NCT04688918 Recruiting - Clinical trials for Pediatric Thoracoscopy

Retrolaminar Block for Pediatric Thoracoscopic Sympathectomy

Start date: January 3, 2021
Phase: N/A
Study type: Interventional

Thoracoscopic sympathectomy is a rapid and simple technique associated with rare complications, but it is associated with severe postoperative pain that makes breathing and coughing difficult resulting in increased occurrence of pulmonary complications. Paravertebral block has frequently been performed for this procedure but its technical difficulty and safety profile may represent a limitation of its routine use. This prospective, randomized, double-blind controlled study is designed to compare the postoperative analgesic efficacy of ultrasound-guided thoracic retrolaminar block (TRLB) with the paravertebral block in children undergoing thoracoscopic sympathectomy. We hypothesize that ultrasound-guided thoracic retrolaminar block may comparable analgesic effect to paravertebral block with a lesser incidence of complications in pediatric patients undergoing thoracoscopic sympathectomy.

NCT ID: NCT04686448 Recruiting - Procedural Sedation Clinical Trials

Ketofol Versus Fenofol as Procedural Sedation for Carpal Tunnel Release

Start date: January 1, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

There are different methods of anesthesia for CTR surgery. Procedural sedation will allow rapid recovery and fewer complications than regional or general anesthesia (GA). Attempts have been made in the past to use additives with propofol to reduce its dose. Ketofol (ketamine/propofol combination) was used for procedural sedation and analgesia. Ketamine and propofol administered in combination have offered effective sedation for spinal anesthesia and for gynecologic, ophthalmologic, and cardiovascular procedures in all age groups. The opposing hemodynamic and respiratory effects of each drug may enhance the utility of this drug combination, increasing both safety and efficacy and allowing reduction in the dose of propofol required to achieve sedation. Propofol alone had a significantly greater number of apnea with desaturation (SpO2 < 90%) episodes. Further, it has been shown that during colonoscopies, propofol in combination with fentanyl provided similar patient satisfaction with shorter recovery times even at lower depths of sedation as compared to propofol. The addition of fentanyl to propofol has been shown to result in better operator feasibility with no difference in recovery time, cognitive impairment, or complications as compared to the use of propofol only for sedation.

NCT ID: NCT04684680 Recruiting - Oligohydramnios Clinical Trials

The Role of Zamzam Water in Idiopathic Oligohydramnios

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the efficacy of drinking zamzam water versus tap water in increasing the AF index in women with oligohydramnios.

NCT ID: NCT04683419 Recruiting - Pleural Effusion Clinical Trials

Modified Thoracoscopic Pleural Cryobiopsy in Diagnosis of Exudative Pleural Effusion

Start date: November 11, 2020
Phase: N/A
Study type: Interventional

Background: Rigid thoracoscopy is the gold standard tool for diagnosing exudative pleural effusion but sometimes it is difficult to obtain sufficient biopsies using the conventional forceps. Objectives: This study evaluated the efficacy, safety and diagnostic value of a modified technique using cryoprobe to obtain pleural biopsies during thoracoscopy. Methods: This is a single center prospective study in patients who will undergo rigid thoracoscopy using conventional rigid forceps followed by a cryoprobe from the same site after injection of subpleural mixture of adrenaline and xylocaine. Biopsies will be reviewed by an independent pathologist; any complications will be recorded, and all patients will be followed up post procedure.

NCT ID: NCT04681053 Recruiting - COVID-19 Clinical Trials

Inhaled Ivermectin and COVID-19

CCOVID-19
Start date: February 25, 2021
Phase: Phase 3
Study type: Interventional

Coronavirus disease-19 is global healthcare crisis. Till May 20, 2020, there were approximately 4,789,205 cases and 318,789 related mortalities were identified globally. This dramatic situation led to healthcare service collapse in many countries. Each country developed its own action plan depending on healthcare expertise and the available resources. There is no definitive therapy for Coronavirus disease-19 up till now. Many current and investigational drugs are used nowadays. Recent reports suggest a beneficial role of Ivermectin in the management of Coronavirus disease-19. A notice that necessitates further clinical studies. The aim of this study is to assess the efficacy and safety of the usage of inhaled ivermectin in the management of Coronavirus disease-19.

NCT ID: NCT04680702 Recruiting - Clinical trials for Metabolic Syndrome , Sims Score and Pediatrics

Metabolic Syndrome and Sims Score

Start date: December 15, 2020
Phase: N/A
Study type: Interventional

SiMSscore was used as a simple and accurate method for Quantifying Metabolic Syndrome in adults , Developed siMS score was calculated using formula: siMS score = 2*Waist/Height + Gly/5.6 + Tg/1.7 + TAsystolic/130-HDL/1.02 or 1.28 (for male or female subjects, respectively),However studies on siMSscor in pediatric was done . PsiMSscore(pediatric sims score) calculated using formula: (2xWaist/Height) + (Glucose(mmol/l)/5.6) + (triglycerides(mmol/l)/1.7) + (Systolic BP/130)-(HDL(mmol/l)/1.02(Soldatovic etal;2016).

NCT ID: NCT04676139 Recruiting - Nocturnal Enuresis Clinical Trials

The Safety and Efficacy of Fluoxetine for Refractory Primary Mono-symptomatic Nocturnal Enuresis in Children

Start date: July 1, 2020
Phase: Phase 3
Study type: Interventional

To determine whether there is a role for the selective serotonin reuptake inhibitors, fluoxetine, as therapy in the treatment of refractory primary monosymptomatic nocturnal enuresis in children , and whether there are side effects involved.

NCT ID: NCT04673201 Recruiting - Clinical trials for Steroid-Induced Glaucoma

Management Steroid Induced Glaucoma

Start date: November 21, 2020
Phase: N/A
Study type: Interventional

Purpose: To assess the safety and efficacy of Viscotrabeculotomy Versus trabeculectomy with MMC for the management of medically uncontrolled steroid induced glaucoma. Patients and methods: A retrospective review of 86 eyes of 67 patients with medically uncontrolled SIG who underwent either viscotrabeculotomy (VT) or trabeculectomy with MMC (Trab-MMC) at Mansoura Ophthalmic Center (Mansoura, Egypt) between January 2008, and December 2017 was conducted. Keywords: Steroid induced glaucoma, trabeculectomy, trabeculotomy and MMC.