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NCT ID: NCT00203554 Completed - Pain Clinical Trials

Percutaneous Vertebroplasty Versus Conservative Treatment of Pain

Start date: March 2004
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effect of vertebroplasty with that of traditional medical treatment in the treatment of painful vertebral fractures in osteoporotic patients.

NCT ID: NCT00200005 Completed - Clinical trials for Fecal Incontinence and Constipation

Sacral Nerve Stimulation for Anal Incontinence and Bowel Control

MDT-301
Start date: November 1998
Phase: Phase 4
Study type: Interventional

Multicenter European study to evaluate efficacy and safety of sacral nerve stimulation with InterStim Therapy to treat fecal incontinence or constipation

NCT ID: NCT00197938 Completed - Septic Shock Clinical Trials

Lactic Acid in the Rectum and Life-Threatening Infection

Start date: November 2005
Phase: N/A
Study type: Observational

Life-threatening infection impairs bloodflow to the gut, thereby causing less delivery of oxygen. This leads to increased formation of lactic acid. The investigators hypothesize, that the more serious the condition, the higher the concentration of lactic acid will be, thus relating to the risk of multiple organ failure or death.

NCT ID: NCT00197912 Completed - Advanced Melanoma Clinical Trials

Dendritic Cell Based Therapy of Malignant Melanoma

Start date: September 2004
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of the study is to show if vaccination with autologous dendritic cells pulsed with peptides or tumor lysate in combination with adjuvant cytokines and Cyclophosphamide can induce a measurable immune response in patients with metastatic malignant melanoma, and to evaluate the clinical effect (objective response rate) of the vaccination regime.

NCT ID: NCT00197886 Completed - Septic Shock Clinical Trials

Dose of Norepinephrine and the Concentration of L-Lactate in the Rectum and Stomach in Patients With Septic Shock.

Start date: October 2004
Phase: N/A
Study type: Interventional

Norepinephrine is a drug used to increase blood pressure in patients with life-threatening infection. However, norepinephrine may limit the bloodflow to the gut, thereby causing relative lack of oxygen to the cells. This leads to increased formation of lactic acid. This study examines whether increasing the dose of norepinephrine leads to higher concentrations of lactic acid in the rectum and stomach in patients with life-threatening infection.

NCT ID: NCT00197860 Completed - Clinical trials for Advanced Renal Cell Carcinoma

Dendritic Cell Based Therapy of Renal Cell Carcinoma

Start date: September 2004
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to show if vaccination with autologous dendritic cells pulsed with peptides or tumor lysate in combination with adjuvant cytokines can induce a measurable immune response in patients with metastatic renal cell carcinoma, and to evaluate the clinical effect (objective response rate) of the vaccination regime.

NCT ID: NCT00196794 Completed - Diarrhea Clinical Trials

A Study of GT267-004 Versus Vancomycin and GT267-004 Versus Metronidazole in Patients With C. Difficile-Associated Diarrhea

Start date: April 2005
Phase: Phase 3
Study type: Interventional

Approximately 520 patients will be entered into this study taking place throughout Australia and Europe. This study aims to determine if an investigational drug is safe and effective for treating symptoms of C. difficile-associated diarrhea (CDAD) and lowering the risk of repeat episodes of CDAD. The investigational drug will be evaluated in comparison to current standard antibiotic treatment, so all patients will receive active medication. All study related care is provided including doctor visits, physical exams, laboratory tests, and study medication. The total length of participation is approximately 6 weeks.

NCT ID: NCT00196755 Completed - Clinical trials for Chronic Kidney Disease

Study of Safety and Efficacy of Renagel® Compared With Calcium Acetate in Patients With Peritoneal Dialysis

Start date: December 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate that sevelamer hydrochloride is non-inferior to calcium acetate for the treatment of hyperphosphataemia in patients receiving peritoneal dialysis.

NCT ID: NCT00195715 Completed - Crohn's Disease Clinical Trials

Long-term Safety and Tolerability Study of Adalimumab in Subjects With Crohn's Disease

Start date: September 2004
Phase: Phase 3
Study type: Interventional

To evaluate the long-term maintenance of response, safety and tolerability of repeated administration of adalimumab in subjects with Crohn's disease who participated in and successfully completed Protocol M02-404 or Protocol M04-691.

NCT ID: NCT00195663 Completed - Clinical trials for Early Rheumatoid Arthritis

Efficacy and Safety of Adalimumab and Methotrexate (MTX) Versus MTX Monotherapy in Subjects With Early Rheumatoid Arthritis

PREMIER
Start date: December 2000
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess the safety and efficacy of adalimumab in combination with methotrexate in patients with recent onset rheumatoid arthritis (RA), and to assess the long-term safety and maintenance of efficacy after treatment with adalimumab for up to 10 years.